Why do standard painkillers often fail to relieve chronic gut pain (Medscape AI)

https://www.medscape.com/ai-search?query=Why%20do%20standard%20painkillers%20often%20fail%20to%20relieve%20chronic%20gut%20pain&ecd=mkm_ret_251214_mscpmrk_gastro_GI-disorders_etid7952640&uac=148436CN&impID=7952640 Chronic gut pain frequently persists despite treatment with conventional analgesics because its underlying mechanisms differ from those targeted by standard painkillers.