OpenSAFELY: factors associated with COVID-19 death in 17 million patients EJ Williamson et al, Nature, July 8, 2020

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 Coronavirus

OpenSAFELY: factors associated with COVID-19 death in 17 million patients
EJ Williamson et al, Nature, July 8, 2020

Primary care records of 17,278,392 adults were pseudonymously linked to 10,926 COVID-19-related deaths. COVID-19-related death was associated with: being male (hazard ratio (HR) 1.59, 95% confidence interval (CI) 1.53–1.65); older age and deprivation (both with a strong gradient); diabetes; severe asthma; and various other medical conditions.

Molecular tracing of SARS-CoV-2 in Italy in the first three months of the epidemic
A Lai et al, MEDRXIV, July 7, 2020

Early Detection Of COVID-19 Using A Smartwatch
T Mishra et al, MEDRXIV, July 7, 2020

Are men dying more than women by COVID-19?
TP de Melo et al, MEDRXIV, July 7, 2020

The usefulness of SARS-CoV-2 test positive proportion as a surveillance tool
MD Hitchings et al, MEDRXIV, July 7, 2020

The implications of silent transmission for the control of COVID-19 outbreaks.
Moghadas Seyed M et al. Proceedings of the National Academy of Sciences of the United States of America 2020 Jul

We evaluate the contribution of presymptomatic and asymptomatic transmission based on recent individual-level data regarding infectiousness prior to symptom onset and the asymptomatic proportion among all infections. We found that the majority of incidences may be attributable to silent transmission.

SARS-CoV-2 titers in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases
F Wu et al, MEDRXIV, July 6, 2020

COVID-Tracking Apps Proliferate, But Will They Really Help?
BJ Wolfson, California Healthline, July 7, 2020

The app developers, and the public health experts who are watching closely, worry that if they do not engage enough people, the apps will fail to catch a significant number of infections and people at risk of infection. Their success relies on levels of compliance and public health competence that have been sorely lacking in the U.S. during the COVID crisis.