CIENCIASMEDICASNEWS: Medical News | Medical Articles: Advancements Disrupting ChIP Assay Technology

viernes, 5 de julio de 2019

Medical News | Medical Articles: Advancements Disrupting ChIP Assay Technology

	July 3, 2019
	Genetics
	The latest Genetics news from News Medical

AdvancementsDisrupting ChIP Assay Technology

Complex sequencing data can be obtained from ChIP-seq of significantly lower amounts of starting material. The high yield of DNA allows NGS sequencing from a single IP from as little as 1000 cells without any need for sample pooling. Higher input DNA improves NGS library complexity.

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			Scientists make breakthrough in understanding the genetics of common syndromic autism Australian and Chilean scientists have made a breakthrough in their understanding of the genetics of a common form of syndromic autism – and they hope their work could one day lead to the development of treatments for the condition.

	Creating a physical and genetic map of Cannabis sativa The Cannabis sativa plant is commonly used for a variety of medicinal, agricultural, industrial and recreational purposes around the world. Despite its widespread use, there remains little genetic information that provides supportive evidence on its medicinal, chemical and/or psychoactive properties.

	Relying strictly on genetic data from European descent may increase health care disparities Relying strictly on genetic data from those of European descent, rather than more diverse populations, can exacerbate existing disease and increase health care disparities, according to new research.

	New study provides insights into genetics and behavior of the Caucasian Lynx Little is known about the biology and the genetic status of the Caucasian Lynx (Lynx lynx dinniki), a subspecies of the Eurasian lynx distributed across portions of Turkey, the Caucasus region and Iran. To collect baseline genetic, ecological, and behavioral data and assist future conservation efforts, a team of scientists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) collected data and samples in a region of Anatolian Turkey over several years.

	Researchers identify genetic mutation that causes fatal response to HAV infection Researchers have identified a genetic mutation that caused an 11-year-old girl to suffer a fatal reaction to infection with the Hepatitis A virus (HAV). The study, which will be published June 18 in the Journal of Experimental Medicine, reveals that mutations in the IL18BP gene causes the body's immune system to attack and kill healthy liver cells, and suggests that targeting this pathway could prevent the deaths of patients suffering rapid liver failure in response to viral infection.

	New genetic marker linked to higher risk of premenopausal breast cancer University of Alberta researchers have added a new genetic marker to the breast cancer map, helping to expand the list of genetic mutations clinicians can watch for in cancer screenings. The genetic marker--called rs1429142--was found to confer a higher risk of breast cancer in Caucasian women carrying the genetic variation compared to women without the variation.

	Study reveals genetic signature of failed immune response to cancer Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn't act quickly or strongly enough. In a study published in The Journal of Clinical Investigation, researchers from the University of Montreal Hospital Research Centre (CRCHUM) revealed the genetic signature of this failed immune response for the first time.