martes, 26 de junio de 2018

Acta Neuropathologica Communications | Home page

Acta Neuropathologica Communications | Home page


Featured video: Another mechanism for the initiation and progression of Parkinson's disease

A research team in the USA and China identifies a potential disease mechanism in the initiation and development of Parkinson’s disease. 


  1. Content Type:Research

    Authors:Melike Pekmezci, Javier E. Villanueva-Meyer, Benjamin Goode, Jessica Van Ziffle, Courtney Onodera, James P. Grenert, Boris C. Bastian, Gabriel Chamyan, Ossama M. Maher, Ziad Khatib, Bette K. Kleinschmidt-DeMasters, David Samuel, Sabine Mueller, Anuradha Banerjee, Jennifer L. Clarke, Tabitha Cooney…
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Featured article: Novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease

Dr. Finkelstein et al report the preclinical characterization of PBT434, a novel quinazolinone compound bearing a moderate affinity metal-binding motif, which is in development for Parkinsonian conditions.

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