NCTR Publications > NCTR Research Highlights

NCTR Publications > NCTR Research Highlights

Current Highlight from November 18, 2016

Minimally Invasive Biomarkers of Anesthetic-Induced Neurotoxicity      
 

NCTR scientists have published a review article on the use of positron emission tomography (PET) to repeatedly monitor anesthetic-induced neurotoxicity during brain development. PET technology offers the advantage of a minimally-invasive approach that can accurately target known molecular and cellular events using specific tracers in longitudinal studies. PET approaches are also translational in nature as they, theoretically, can be used in pediatric populations.  This review further discusses general anesthetic-induced neurotoxicity in the developing brain as assayed using microPET imaging techniques in preclinical studies. The article is available online at Neurotoxicology and Teratology. 

For more information, please contact Xuan Zhang, Division of Neurotoxicology, FDA/NCTR.  

NCTR Research Highlights Archives

• 2016-NCTR Research Highlights
• 2015-NCTR Research Highlights
• 2014-NCTR Research Highlights [ARCHIVED]
• 2013-NCTR Research Highlights [ARCHIVED]
• 2012-NCTR Research Highlights [ARCHIVED]
• 2011-NCTR Research Highlights [ARCHIVED]
• 2010-NCTR Research Highlights [ARCHIVED]
• 2009-NCTR Research Highlights [ARCHIVED]
• 2008-NCTR Research Highlights [ARCHIVED]
• 2007-NCTR Research Highlights [ARCHIVED]
• 2006-NCTR Research Highlights [ARCHIVED]

Contact FDA

870-543-7000

National Center for Toxicological Research

Food and Drug Administration

3900 NCTR Road

Jefferson, AR 72079