ESR1 Mutations in Cell-Free DNA of Breast Cancer | Breast Cancer | JAMA Oncology | The JAMA Network

ESR1 Mutations in Cell-Free DNA of Breast Cancer | Breast Cancer | JAMA Oncology | The JAMA Network

October 2016

ESR1 Mutations in Cell-Free DNA of Breast CancerPredictive “Tip of the Iceberg”

Suzanne A. W. Fuqua, PhD¹; Yassine Rechoum, PhD¹; Guowei Gu, PhD¹

Author Affiliations

JAMA Oncol. 2016;2(10):1315-1316. doi:10.1001/jamaoncol.2016.1268

Public Health Genomics Knowledge Base (v1.2)

Last Posted: Nov-10-2016 11AM

 Liquid Biopsy expanded expanded

The cancer bloodhounds
Nature Biotechnology, November 2016

ESR1 Mutations in Cell-Free DNA of Breast Cancer Predictive “Tip of the Iceberg"
Suzanne A. W. Fuqua et al, JAMA Oncology, August 11, 2016

Prevalence of ESR1 Mutations in Cell-Free DNA and Outcomes in Metastatic Breast Cancer A Secondary Analysis of the BOLERO-2 Clinical Trial
Sarat Chandarlapaty, et al, JAMA Oncology, August 11, 2016

More information on this topic

Last Updated: Nov 08, 2016

• The cancer bloodhounds
  Nature Biotechnology, November 2016
• Detection of the T790M mutation of EGFR in plasma of advanced non-small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors (West Japan oncology group 8014LTR study).
  Takahama Takayuki, et al. Oncotarget 2016 8
• ESR1 Mutations in Cell-Free DNA of Breast Cancer Predictive “Tip of the Iceberg"
  Suzanne A. W. Fuqua et al, JAMA Oncology, August 11, 2016
• Prevalence of ESR1 Mutations in Cell-Free DNA and Outcomes in Metastatic Breast Cancer A Secondary Analysis of the BOLERO-2 Clinical Trial
  Sarat Chandarlapaty, et al, JAMA Oncology, August 11, 2016
• Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma.
  Rachiglio Anna Maria, et al. Oncotarget 2016 7
• Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study.
  Pu Dan, et al. Thoracic cancer 2016 7 (4) 428-36
• The Holy Grail of Liquid Biopsies
  Genome Magazine, June 23, 2016
• Blood Test for Genetic Changes in Tumors Shows Promise as Alternative to Tumor Biopsy
  NCI, June 14, 2016
• Detection of TP53/PIK3CA Mutations in Cell-Free Plasma DNA From Metastatic Breast Cancer Patients Using Next Generation Sequencing.
  Nakauchi Chiaki, et al. Clinical breast cancer 2016 5
• ASCO 2016: Liquid Biopsy May Help Guide Treatment Decisions for Patients With Advanced Solid Tumors
  ASCO Post, June 4, 2016
• ‘Liquid biopsy’ study offers hope for a blood test to find cancer
  L McGinley, Washington Post, June 4, 2016
• AR-V7 Protein in Circulating Tumor Cells—The Decider for Therapy
  RB Montgomery et al, JAMA Oncology, June 4, 2016
• K-Ras mutation detection in liquid biopsy and tumor tissue as prognostic biomarker in patients with pancreatic cancer: a systematic review with meta-analysis.
  Li Tao, et al. Medical oncology (Northwood, London, England) 2016 7 (7) 61
• The Quest for a Simple Cancer Test
  J Perkle, NOvaNExt, PBS, May 19, 2016
• The tumour trail left in blood
  KR Chi, Nature News, April 13, 2016

• Human (12)
• Pathogen (0)

• Human (11)
• Pathogen (0)

• Human (3)
• Pathogen (0)

Relevant Resources

• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB