Public Health Sciences

The Office of Public Health Genomics (OPHG) provides updated and credible information on how genomic
information and family health history can improve health and influence policy and practice. We highlight
news and information on the use of genomic tests and other applications, including family health history,
in clinical and public health practice and programs, along with relevant data, policy, and legislation. We hope the update is informative to practitioners, policy makers, consumers, and researchers. Please send
your comments to: genetics@cdc.gov.

Public Health Sciences

• Finding the missing heritability in pediatric obesity: the contribution of genome-wide complex trait analysis.
  Llewellyn CH, et al Int J Obes (Lond). 2013 Mar 26
• From “big epidemiology” to “colossal epidemiology”: When all eggs are in one basket
  Hernán, Miguel A, Savitz, David A. Epidemiology, 2013 May
• Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity
  Eleanor Wheeler, Ni Huang, Elena G Bochukova, et al. Nature Genetics 2013 Apr 7
  
  • Genome wide study identifies genetic variants associated with childhood obesity, Medical Xpress, Apr 7
• GWAS of cerebrospinal fluid tau levels identifies novel risk variants for Alzheimer's disease
  Carlos Cruchaga, John S.K. Kauwe, Oscar Harari, et al. Neuron 2013 Apr 4
  
  • Predicting risk for Alzheimer's disease with new genetic markers, Medical News Today, Apr 7
• IL-6 polymorphisms: a useful genetic tool for inflammation research?
  Woo P, Humphries SE. J Clin Invest. 2013 Apr 1;123(4):1413-4
• Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register
  Abugessaisa I, et al. J Transl Med 2013 Apr;11(1):85
• Is size the next big thing in epidemiology?
  Toh, Sengwee; Platt, Richard. Epidemiology, 2013 May
• Making medical decisions in dependence of genetic background: estimation of the utility of DNA testing in clinical, pharmaco-epidemiological or genetic studies
  Nguyen TT, et al. Genet Epidemiol 2013 Apr