domingo, 5 de agosto de 2012

Stakeholder perspectives on decision-analytic mode... [Genet Med. 2012] - PubMed - NCBI

Stakeholder perspectives on decision-analytic mode... [Genet Med. 2012] - PubMed - NCBI

2012 Jul 26. doi: 10.1038/gim.2012.92. [Epub ahead of print]

Stakeholder perspectives on decision-analytic modeling frameworks to assess genetic services policy.


Center for Genomics and Healthcare Equality, University of Washington, Seattle, Washington, USA.


Purpose:Genetic services policymakers and insurers often make coverage decisions in the absence of complete evidence of clinical utility and under budget constraints. We evaluated genetic services stakeholder opinions on the potential usefulness of decision-analytic modeling to inform coverage decisions, and asked them to identify genetic tests for decision-analytic modeling studies.Methods:We presented an overview of decision-analytic modeling to members of the Western States Genetic Services Collaborative Reimbursement Work Group and state Medicaid representatives and conducted directed content analysis and an anonymous survey to gauge their attitudes toward decision-analytic modeling. Participants also identified and prioritized genetic services for prospective decision-analytic evaluation.Results:Participants expressed dissatisfaction with current processes for evaluating insurance coverage of genetic services. Some participants expressed uncertainty about their comprehension of decision-analytic modeling techniques. All stakeholders reported openness to using decision-analytic modeling for genetic services assessments. Participants were most interested in application of decision-analytic concepts to multiple-disorder testing platforms, such as next-generation sequencing and chromosomal microarray.Conclusion:Decision-analytic modeling approaches may provide a useful decision tool to genetic services stakeholders and Medicaid decision-makers.Genet Med advance online publication 26 July 2012.

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