Venous Thromboembolism Prophylaxis in Orthopedic Surgery - Research Review - Final | AHRQ Effective Health Care Program

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Venous Thromboembolism Prophylaxis in Orthopedic Surgery - Research Review - Final | AHRQ Effective Health Care Program

AHRQ Evidence Review Addresses Venous Thromboembolism Prophylaxis in Orthopedic Surgery

Extending post-surgical use of medications to prevent blood clots may be beneficial for patients who have undergone major orthopedic surgery such as hip or knee replacement, according to a new AHRQ Effective Health Care Program review. Standard treatment currently calls for the use of anti-clotting medications from seven to 10 days post-surgery; however, the evidence suggests that up to 28 days or longer may be appropriate. While there is not enough evidence to determine which type of anti-clotting medication is best, within the heparin class of medications, low molecular-weight heparin was found to be superior to unfractioned heparin. More research, particularly clinical trials, is needed to compare the effectiveness of using single or combination therapies, including medications or mechanical prophylaxis, such as leg compression or foot pumps, and to evaluate the use of medications after less serious types of orthopedic surgery. Select to access the review.

Venous Thromboembolism Prophylaxis in Orthopedic Surgery

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