Gut microbiome differences may explain varied sleep responses to hydrogen supplementation

https://www.news-medical.net/news/20261023/Gut-microbiome-differences-may-explain-varied-sleep-responses-to-hydrogen-supplementation.aspx Hiroshima University researchers investigated the effects of hydrogen supplementation on sleep quality in healthy human volunteers. While hydrogen supplementation had no significant effect compared to a placebo, individuals in the hydrogen-supplementation group reporting better sleep quality were discovered to have a lower abundance of hydrogen producing bacteria in their gut microbiome. A Hiroshima University-led randomized, double-blind clinical trial found that hydrogen supplementation did not significantly improve sleep quality compared to a placebo; however, exploratory analyses suggest that differences in the abundance of hydrogen-producing gut bacteria may be associated with individual differences in sleep-related responses.