New gene therapy strategy uses the brain's own glymphatic transport system for drug delivery

https://www.news-medical.net/news/20260708/New-gene-therapy-strategy-uses-the-brains-own-glymphatic-transport-system-for-drug-delivery.aspx A new study describes a gene therapy strategy that uses the brain's own glymphatic transport system to distribute engineered viral vectors throughout the brain. The approach addresses two major challenges in neurological medicine-reaching therapeutic targets behind the blood-brain barrier and limiting unwanted effects elsewhere in the body-and could pave the way for new treatments for diseases including multiple sclerosis, Huntington's disease, and rare childhood white matter disorders.