Dear Colleague,
The MMWR of the 2010 STD Treatment Guidelines published electronically on December 17, 2010 contains incorrect dosage information. MMWR will issue an erratum this week. Three significant corrections pertain to the recommended regimens for gonococcal infections, which include gonococcal dual therapy, and the alternative regimens for bacterial vaginosis. The corrected dosages are highlighted in the three regimen boxes below:
Uncomplicated Gonococcal Infections of the Cervix, Urethra, and Rectum
Recommended Regimens
Ceftriaxone 250 mg IM in a single dose
OR, IF NOT AN OPTION
Cefixime 400 mg orally in a single dose
OR
Single-dose injectible cephalosporin regimens
PLUS
Azithromycin 1g orally in a single dose
OR
► Doxycycline 100 mg orally twice a day for 7 days
Uncomplicated Gonococcal Infections of the Pharynx
Recommended Regimens
Ceftriaxone 250 mg IM in a single dose
PLUS
Azithromycin 1g orally in a single dose
OR
► Doxycycline 100 mg orally twice a day for 7 days
Bacterial Vaginosis
Alternative Regimens
► Tinidazole 2 g orally once daily for 2 days
OR
Tinidazole 1 g orally once daily for 5 days
OR
Clindamycin 300 mg orally twice daily for 7 days
OR
Clindamycin ovules 100 mg intravaginally once at bedtime for 3 days
Corrected pages to the print version (pages 50, 51, and 57) of the MMWR are available on the Division of STD Prevention website at http://www.cdc.gov/std/treatment/2010/. Apologies for any inconvenience or confusion these errors may have caused.
Sincerely,
Raul
Raul A. Romaguera, DMD, MPH
Associate Director for Policy, Planning and External Relations (Acting)
Division of STD Prevention
Centers for Disease Control and Prevention
jueves, 13 de enero de 2011
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