AI helps uncover new antibiotic candidates against drug-resistant gonorrhea The approach identifies entirely new chemical structures that could help replenish a thinning antibiotic pipeline as resistance continues to rise. Written byBree Foster, PhD

AI helps uncover new antibiotic candidates against drug-resistant gonorrhea The approach identifies entirely new chemical structures that could help replenish a thinning antibiotic pipeline as resistance continues to rise. Written byBree Foster, PhD https://www.drugdiscoverynews.com/ai-helps-uncover-new-antibiotic-candidates-against-drug-resistant-gonorrhea-17274 A new study demonstrated how AI can help identify novel antibiotic candidates against one of the world’s most persistent and rapidly evolving infections: gonorrhea. Published in Science Translational Medicine, the work shows that deep learning models can successfully navigate millions of chemical structures to pinpoint compounds with activity against Neisseria gonorrhoeae, including strains resistant to multiple existing antibiotics. The findings point to a potential new strategy for replenishing a shrinking antibiotic pipeline as resistance continues to erode standard treatments.