Editorial p1 A new year brings new opportunities The Lancet Respiratory Medicine +++ +...

Association of medication-induced deep sedation and emotional distress during mechanical ventilation with loss of independent living: an observational cohort study Karuna Wongtangman, MDa,b ∙ Felix Borngaesser, MDa,c ∙ Maíra I Rudolph, MDa,d ∙ Flora T Scheffenbichler, MDa,e ∙ Michael E Kiyatkin, MDa ∙ Ibraheem M Karaye, DrPHa,f ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00264-4/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz--zgztd7ZuUkkTyK9GjCU6ja-Qap87fXzs8C0_l3J14I-v3sZIY_SCQuiPO65JVF8RApfSkMGohPZpTTB9dvhXTX1bdrw&_hsmi=398072522&utm_content=397506486&utm_source=hs_email Effect of elexacaftor–tezacaftor–ivacaftor on bronchial dilatations in adolescents with cystic fibrosis: a multicentre prospective observational study Prof Isabelle Sermet-Gaudelus, PhDa,b,c isabelle.sermet@aphp.fr ∙ Alexia Letierce, PhDd,* ∙ Laureline Berteloot, MDe,* ∙ Anne-Sophie Bonnel, MDa,f ∙ Yuxin Chen, PhDg ∙ Punit Makani, MScg ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00248-6/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz--TJ7mE5AQItti8o2VeYZT75o1AwgzKYfZWWXkHkANvyZlkhDQi-NknJHQ0127B8_UhIpMoEEWn2Iwms-gYw7HrIjDP3Q&_hsmi=398072522&utm_content=397506486&utm_source=hs_email Effects of intraoperative higher versus lower positive end-expiratory pressure during one-lung ventilation for thoracic surgery on postoperative pulmonary complications (PROTHOR): a multicentre, international, randomised, controlled, phase 3 trial The Writing Committee* ∙ Steering Committee† of the PROTHOR Collaborative Group‡ of the PROtective VEntilation Network (PROVE Network) for the Clinical Trial Network of the European Society of Anaesthesiology and Intensive Care https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00330-3/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz-8ZOEFM9f2uZGs51YJe6gizXRIMXE1G_6GeWBNwv6Rgj5clQcP3pdZBIsQfNKU3u6nqGdruav8rXhbXPXvVjinN6h4wBw&_hsmi=398072522&utm_content=397506486&utm_source=hs_email Editorial p1 A new year brings new opportunities The Lancet Respiratory Medicine https://www.thelancet.com/journals/lanres/issue/vol14no1/PIIS2213-2600(25)X0013-8