Does epithelial cell extrusion explain why traditional asthma therapies fail to prevent airway remodeling? (Medscape AI)

https://www.medscape.com/ai-search?query=Does%20epithelial%20cell%20extrusion%20explain%20why%20traditional%20asthma%20therapies%20fail%20to%20prevent%20airway%20remodeling%3F&ecd=mkm_ret_251228_mscpmrk_pulm_best-of-the-year_etid7981461&uac=148436CN&impID=7981461 Recent data suggest that repetitive mechanical injury to the airway epithelium—specifically, *cell extrusion* during bronchoconstrictive events—may drive a cycle of epithelial damage, inflammation, and eventual remodelling that is not adequately addressed by standard anti-inflammatory or bronchodilator therapies.