What is the seizure risk with tramadol and antidepressants (AI) + +++++

https://www.medscape.com/ai-search?query=What%20is%20the%20seizure%20risk%20with%20tramadol%20and%20antidepressants&ecd=mkm_ret_251101_mscpmrk_psych_addiction_etid7842194&uac=148436CN&impID=7842194 Tramadol lowers the seizure threshold, and concomitant use with certain antidepressants—particularly those that inhibit CYP2D6—can further increase seizure risk in vulnerable populations. OPIOID MANAGEMENT Novel Benzos May Up OUD Overdose Severity https://www.medscape.com/viewarticle/novel-benzodiazepines-linked-greater-severity-opioid-2025a1000mzt?ecd=mkm_ret_251101_mscpmrk_psych_addiction_etid7842194&uac=148436CN&impID=7842194 Is Tramadol Right for Pain? New Findings https://www.medscape.com/viewarticle/time-reconsider-tramadol-chronic-pain-2025a1000ria?ecd=mkm_ret_251101_mscpmrk_psych_addiction_etid7842194&uac=148436CN&impID=7842194 Improving Opioid Overdose Recovery https://www.medscape.com/viewarticle/can-peer-support-after-opioid-overdose-boost-recovery-2025a1000oa3?ecd=mkm_ret_251101_mscpmrk_psych_addiction_etid7842194&uac=148436CN&impID=7842194 Promising Treatment in Perinatal OUD https://www.medscape.com/viewarticle/extended-release-buprenorphine-shows-promise-perinatal-2025a1000snf?ecd=mkm_ret_251101_mscpmrk_psych_addiction_etid7842194&uac=148436CN&impID=7842194 Opioid Abuse: Practice Essentials https://emedicine.medscape.com/article/287790-overview?ecd=mkm_ret_251101_mscpmrk_psych_addiction_etid7842194&uac=148436CN&impID=7842194