Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage ++ +++

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damageHeavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage https://www.news-medical.net/news/20251020/Heavy-drinking-fuels-Alzheimere28099s-disease-by-igniting-brain-inflammation-and-protein-damage.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration. Social and environmental inequality linked to risk of Alzheimer’sSocial and environmental inequality linked to risk of Alzheimer’s https://www.news-medical.net/news/20251020/Social-and-environmental-inequality-linked-to-risk-of-Alzheimere28099s.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare. Study reveals how a microglial mutation increases risk for Alzheimer's disease https://www.news-medical.net/news/20251017/Study-reveals-how-a-microglial-mutation-increases-risk-for-Alzheimers-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function." Living environment may influence dementia markers in the brainLiving environment may influence dementia markers in the brain https://www.news-medical.net/news/20251015/Living-environment-may-influence-dementia-markers-in-the-brain.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 The conditions where you live may influence your brain health and risk for dementia, according to a new study from Wake Forest University School of Medicine Advanced MRI technique reveals early markers of hereditary frontotemporal dementiaAdvanced MRI technique reveals early markers of hereditary frontotemporal dementia https://www.news-medical.net/news/20251016/Advanced-MRI-technique-reveals-early-markers-of-hereditary-frontotemporal-dementia.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 An international study led by researchers at Karolinska Institutet in Sweden demonstrates that it is possible to detect subtle changes in the brain and identify early signs of hereditary frontotemporal dementia using advanced brain imaging techniques