viernes, 31 de octubre de 2025

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

https://www.news-medical.net/news/20251031/Evidence-of-previously-unrecognized-hub-in-the-brains-lymphatic-drainage-system-revealed.aspx

Sensory effects of flavanols trigger physiological responses in the brain

https://www.news-medical.net/news/20251031/Sensory-effects-of-flavanols-trigger-physiological-responses-in-the-brain.aspx

Researchers visualize how brain network development is altered in rare childhood disorder

https://www.news-medical.net/news/20251031/Researchers-visualize-how-brain-network-development-is-altered-in-rare-childhood-disorder.aspx

Obesity treatment in the UK could become a "two-tier system", experts warn

https://www.news-medical.net/news/20251031/Obesity-treatment-in-the-UK-could-become-a-two-tier-system-experts-warn.aspx

Bacterial Extracellular Vesicles and Their Role in PCOS and Endometriosis Explained

https://www.news-medical.net/health/Bacterial-Extracellular-Vesicles-and-Their-Role-in-PCOS-and-Endometriosis-Explained.aspx Bacterial extracellular vesicles (BEVs) play a crucial role in mediating gut-reproductive communication and immune regulation. Understanding their influence on PCOS and endometriosis reveals new possibilities for non-invasive diagnostics and targeted therapies.

Life expectancy gains are slowing

https://www.news-medical.net/news/20251031/Life-expectancy-gains-are-slowing.aspx After more than a century of steady progress, new research warns that the world’s life expectancy boom is slowing, largely because improvements in early-life mortality have already been achieved.

How real-world evidence is empowering treatment decisions in prostate cancer

https://www.statnews.com/sponsor/2025/10/10/how-real-world-evidence-is-empowering-treatment-decisions-in-prostate-cancer/

Most Read Papers - Cancer Science & Oncogenesis +...

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_251031 Current Approaches to the Management of Rheumatic Diseases in Pregnancy: Risk Stratification, Therapeutic Advances, and Maternal-Fetal Outcomes. Aikaterini-Gavriela Giannakaki, Maria-Nektaria Giannakaki, Anastasia Bothou, Konstantinos Nikolettos, Nikolaos Machairiotis, Kalliopi I Pappa, Panagiotis Tsikouras Journal of Personalized Medicine 2025 September 1

Antibody-Drug Conjugates in Practice: Contemporary Questions for the Treatment of Metastatic Breast Cancer Authors: Judy King, MRCP, PhD; Giuseppe Curigliano, MD, PhD; Peter Schmid, MD, PhD, FRCP

https://www.medscape.org/viewarticle/1002851?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251030-OUS-HONC-1002851-cta

Treating Metastatic Colorectal Cancer in the Second Line and Beyond: Oral Therapy Edition Authors: Rahul Gosain, MD, MBA; Rohit Gosain, MD; John Strickler, MD; Chiara Cremolini, MD, PhD

https://www.medscape.org/viewarticle/1003002?sso=true&impID=7837628&uac=148436CN&src=wnl_tpal_251030_mscpedu

Recognizing Subtle Disability Worsening in Multiple Sclerosis (Part 1): The Role of Smoldering Neuroinflammation Authors: Laura Airas, MD, PhD; Martina Absinta, MD, PhD; Benjamin M. Greenberg, MD, MHS

https://www.medscape.org/viewarticle/1002761_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_251030-ES_LANG-NEUR-1002761-cta

Navigating the Storm of Heavily Pretreated Multiple Myeloma: Calming the Waters With Bispecific Antibodies Authors: Hermann C. Einsele, MD, PhD; Xavier Leleu, MD, PhD; Naresh Bumma, MD

https://www.medscape.org/viewarticle/1002692_sidebar9?sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_251030-ES_LANG-HONC-1002692-cta

COVID mRNA Vaccines Enhance Cancer Immunotherapy: Now What? Megan Brooks October 31, 2025 ++...

https://www.medscape.com/viewarticle/covid-mrna-vaccines-enhance-cancer-immunotherapy-now-what-2025a1000tuz European Society for Medical Oncology (ESMO) Annual Meeting 2025 https://www.medscape.com/viewcollection/37811

Medscape Now! Avoiding Underdiagnosis of Iron Deficiency With and Without Anemia in Adults Authors: ​ CME Author: Naseem Bazargan, MPH

https://www.medscape.org/viewarticle/medscape-now-avoiding-underdiagnosis-iron-deficiency-and-2025a1000sxu?page=1

Conditioning Regimens for HSCT in AML/MDS: Importance of Individualization in Your Adult Patients Authors: Domenico Russo, MD, PhD; Daniele Avenoso, MD, PhD; Matthias Stelljes, MD

https://www.medscape.org/viewarticle/1002516?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251030-OUS-HONC-1002516-cta

Is Diabetes Linked to Dementia? | 1 in 3 Worldwide Have Functional Bowel Disorders +++++ +++

LATEST Is Diabetes Linked to Dementia? Latest Evidence Revealed https://www.medscape.com/viewarticle/diabetes-linked-dementia-latest-evidence-revealed-2025a1000svk?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 Hydrogel Shows Promise as Safe Weight-Loss Option https://www.medscape.com/viewarticle/hydrogel-shows-promise-safe-weight-loss-option-2025a1000sz7?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 1 in 3 Worldwide Have Functional Bowel Disorders https://www.medscape.com/viewarticle/one-three-worldwide-have-functional-bowel-disorders-2025a1000sv2?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 Creatine Supplements in CVD: Helpful Addition to Treatment? https://www.medscape.com/viewarticle/creatine-supplements-cvd-helpful-addition-treatment-2025a1000stw?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 New Guidelines Urge Scoring System to Diagnose Strep Throat https://www.medscape.com/viewarticle/new-guidelines-urge-scoring-system-diagnose-strep-throat-2025a1000snp?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 Business of Medicine 1 in 3 EU Doctors & Nurses Face Depression or Anxiety https://www.medscape.com/viewarticle/who-1-3-eu-doctors-and-nurses-face-depression-or-anxiety-2025a1000t0r?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 What the AI Bubble Is Doing to Healthcare https://www.medscape.com/viewarticle/what-ai-bubble-doing-healthcare-2025a1000t0h?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027 Anti-Obesity Medications Set to Explode Entering 2026 https://www.medscape.com/viewarticle/anti-obesity-medications-set-explode-entering-2026-2025a1000spz?ecd=mkm_ret_251031_mscpmrk-OUS_ICYMI_etid7834027&uac=148436CN&impID=7834027

Routine Childhood HPV Vaccinations Demonstrate Striking Long-Term Benefits ++++

Routine Childhood HPV Vaccinations Demonstrate Striking Long-Term Benefits https://www.medscape.com/viewarticle/routine-childhood-hpv-vaccinations-demonstrate-striking-long-2025a1000pf0?ecd=wnl_edit_tpal_etid7839119&uac=148436CN&impID=7839119 The Rise and Fall and Rise Again of BP Chronotherapy https://www.medscape.com/viewarticle/rise-and-fall-and-rise-again-bp-chronotherapy-2025a1000t3a?ecd=wnl_edit_tpal_etid7839119&uac=148436CN&impID=7839119 Severe Epigastric Pain, Headache, and Fever in a Coffee Drinker https://reference.medscape.com/viewarticle/severe-epigastric-pain-headache-and-fever-coffee-drinker-2025a1000sl5?ecd=wnl_edit_tpal_etid7839119&uac=148436CN&impID=7839119 Office Small Talk: Uncharted Territory https://www.medscape.com/viewarticle/office-small-talk-uncharted-territory-2025a1000t34?ecd=wnl_edit_tpal_etid7839119&uac=148436CN&impID=7839119

Neurogenic Rosacea: Subtype or Symptom on a Spectrum? ++++ +++ +++ +++ +...

COSMETIC PROCEDURES New FDA Warning on RF Microneedling Side Effects https://www.medscape.com/viewarticle/fda-warning-rf-microneedling-side-effects-short-specifics-2025a1000sbs?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Manicures Linked to Adverse Reactions: New Findings https://www.medscape.com/viewarticle/review-finds-nail-cosmetics-often-linked-adverse-reactions-2025a1000tm1?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 A Closer Look at Laser Tattoo Removal https://www.medscape.com/viewarticle/scientists-take-closer-look-laser-tattoo-removal-2025a1000py2?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Botulinum Toxin and Fillers: Consider These Pitfalls https://www.medscape.com/viewarticle/botulinum-toxin-and-fillers-consider-clinical-and-legal-2025a1000op7?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 ACNE & ROSACEA Isotretinoin Replacement for Acne? New Trial Results https://www.medscape.com/viewarticle/do-trial-results-suggest-acne-isotretinoin-replacement-2025a1000qin?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Which Cosmeceuticals are Useful for Acne Tx? https://www.medscape.com/viewarticle/which-cosmeceuticals-are-backed-research-2025a1000o0b?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Biology vs Clinical Evidence: Diet and Acne Link Debated https://www.medscape.com/viewarticle/early-study-finds-extended-release-minoxidil-grows-more-hair-2025a1000q0u?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 ALOPECIA TREATMENTS Alopecia Drug Grows More Hair: New Data https://www.medscape.com/viewarticle/early-study-finds-extended-release-minoxidil-grows-more-hair-2025a1000q0u?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Supplemental Alopecia Txs: Consider Potential Risks https://www.medscape.com/viewarticle/over-counter-adjunctive-alopecia-treatments-consider-their-2025a1000r7i?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Sparse Hair in a Healthy 3-Year-Old Girl: What’s Your Dx? https://reference.medscape.com/viewarticle/sparse-hair-healthy-3-year-old-girl-2025a1000plv?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 DRUG SPOTLIGHT secukinumab https://reference.medscape.com/drug/cosentyx-secukinumab-999964?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 vismodegib https://reference.medscape.com/drug/erivedge-vismodegib-999716?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 apremilast https://reference.medscape.com/drug/otezla-apremilast-999915?ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647 Why does neurogenic rosacea challenge traditional subtype classifications of rosacea https://www.medscape.com/ai-search?query=Why%20does%20neurogenic%20rosacea%20challenge%20traditional%20subtype%20classifications%20of%20rosacea&ecd=mkm_ret_251031_mscpmrk_derm_top-content_etid7837647&uac=148436CN&impID=7837647

EASO Algorithm: Matching Obesity Drugs to Complications +++++++ ++ +...

Trending in October Bisphosphonates for Aromatase Inhibitor Bone Loss https://www.medscape.com/viewarticle/consensus-bisphosphonates-aromatase-inhibitor-bone-loss-2025a1000rta?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 GLP-1s and Libido: An Effect That May Fly Under the Radar https://www.medscape.com/s/viewarticle/glp-1s-and-libido-effect-may-fly-under-radar-2025a1000rbd?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 New Sensor Doesn’t Require Needle to Measure Glucose https://www.medscape.com/viewarticle/biolinq-shine-new-sensor-doesnt-require-needle-measure-2025a1000sab?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 Oral Semaglutide Reduces CV, MALE in T2D Regardless of PAD https://www.medscape.com/viewarticle/oral-semaglutide-reduces-major-adverse-cardiovascular-and-2025a1000q9a?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 Artificial Intelligence’s Evolving Role in Diabetes Care https://www.medscape.com/viewarticle/artificial-intelligences-evolving-role-diabetes-care-2025a1000rik?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 GERD Risk Higher With GLP-1s vs SGLT2s https://www.medscape.com/s/viewarticle/gerd-risk-higher-glp-1s-vs-sglt2s-2025a1000qmz?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 Growth Hormone Benefits Kids With Rare Genetic Condition https://www.medscape.com/viewarticle/growth-hormone-benefits-kids-rare-genetic-condition-2025a1000m8e?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 US Drug Spotlight Exenatide Injectable Solution https://reference.medscape.com/drug/byetta-exenatide-injectable-solution-342892?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 Cabozantinib https://reference.medscape.com/drug/cometriq-cabometyx-cabozantinib-999791?ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531 How does the new EASO algorithm align obesity complications with drug choices https://www.medscape.com/ai-search?query=How%20does%20the%20new%20EASO%20algorithm%20align%20obesity%20complications%20with%20drug%20choices&ecd=mkm_ret_251031_mscpmrk_endo_top-content_etid7839531&uac=148436CN&impID=7839531

Editorial p2033 Health in the US Government shutdown The Lancet +...

Editorial p2033 Health in the US Government shutdown The Lancet https://www.thelancet.com/journals/lancet/issue/vol406no10515/PIIS0140-6736(25)X0044-1

jueves, 30 de octubre de 2025

Morning Briefing: Today's News Summaries Thursday, Oct 30 2025 UPDATED 9:00 AM

https://kffhealthnews.org/morning-briefing/thursday-october-30-2025/

Diagnostics for faster antimicrobial susceptibility testing New phenotypic methods can help identify the best antibiotic to treat sepsis, UTIs, and other bacterial infections.

https://www.drugdiscoverynews.com/diagnostic-for-faster-antimicrobial-susceptibility-testing-16233?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_3FJ0zjz2a3WhHJmmfQkMCTxDJEBvMGWA_gnAiLoiX1qikCrgq5bLhu5JqjLK-G9F2-L_Kv67sXVlGLm4CrRhV0EDWlA&_hsmi=387609120&utm_content=387609120&utm_source=hs_email

Gepotidacin could help fight antibiotic resistance on two fronts After decades of stalled innovation, a new oral antibiotic could now combat both everyday infections and urgent public health threats.

https://www.drugdiscoverynews.com/gepotidacin-could-help-fight-antibiotic-resistance-on-two-fronts-16573?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_e4nkb-nCkQEtcyptGBVoSUkZD0r6UU2Cm9VrNr-ap4ahX4d46cdH_cODkJTddtMZJj8CAYdXjBOGumPCiTFPfOFsDJQ&_hsmi=387609120&utm_content=387609120&utm_source=hs_email

Breaking the bacterial barrier to fight antimicrobial resistance Researchers are turning bacterial transport systems from obstacles into opportunities for targeted therapy.

https://www.drugdiscoverynews.com/breaking-the-bacterial-barrier-to-fight-antimicrobial-resistance-16768?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--432Mh9t58XvxV6nGdmhH5U4nTIzkE7p1CFfUdPLviGyF5rNhiY68TFNxKNO0jPFhkLuRuUd9td8guwFyMP2yATlGlKw&_hsmi=387609120&utm_content=387609120&utm_source=hs_email

New NIA grant advances tools for dementia caregiving +++ +++ +

New NIA grant advances tools for dementia caregiving https://www.news-medical.net/news/20251015/New-NIA-grant-advances-tools-for-dementia-caregiving.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 New NIA grant advances tools for dementia caregivingMore than 7 million Americans live with Alzheimer's disease and related dementias (ADRD), supported by 12 million unpaid family caregivers whose contributions are valued at $413 billion annually. The role of SignalChem’s Tau proteins in fast-tracking neurodegenerative research https://www.news-medical.net/whitepaper/20251016/The-role-of-SignalCheme28099s-Tau-proteins-in-fast-tracking-neurodegenerative-research.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 The role of SignalChem’s Tau proteins in fast-tracking neurodegenerative researchExplore how SignalChem’s Tau proteins are accelerating breakthroughs in neurodegenerative research. New research helps explain how the brain implements visual working memory https://www.news-medical.net/news/20251021/New-research-helps-explain-how-the-brain-implements-visual-working-memory.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 New research helps explain how the brain implements visual working memoryImagine you are a security guard in one of those casino heist movies where your ability to recognize an emerging crime will depend on whether you notice a subtle change on one of the many security monitors arrayed on your desk. Discovery explains why women face higher risk of Alzheimer’s and multiple sclerosis https://www.news-medical.net/news/20251015/Discovery-explains-why-women-face-higher-risk-of-Alzheimere28099s-and-multiple-sclerosis.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Discovery explains why women face higher risk of Alzheimer’s and multiple sclerosisNew research by UCLA Health has identified a sex-chromosome linked gene that drives inflammation in the female brain, offering insight into why women are disproportionately affected by conditions such as Alzheimer's disease and multiple sclerosis as well as offering a potential target for intervention. Nanopore sensing of protein and peptide conformation for healthcare https://www.azosensors.com/article.aspx?ArticleID=3255&utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Nanopore sensing of protein and peptide conformation for healthcareNanopore sensors enable precise protein and peptide analysis, crucial for early disease diagnosis and advancing personalized healthcare solutions. Cellular switches direct supplies during memory formation https://www.azolifesciences.com/news/20251015/Cellular-Switches-Direct-Supplies-During-Memory-Formation.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Cellular switches direct supplies during memory formationWhen we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. The biological tagging of astrocytes enhances memory recall https://www.azolifesciences.com/news/20251016/The-Biological-Tagging-of-Astrocytes-Enhances-Memory-Recall.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 The biological tagging of astrocytes enhances memory recallWhy are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer.

Sertraline contributes to a modest improvement in core depression and anxiety symptoms

https://www.news-medical.net/news/20251030/Sertraline-contributes-to-a-modest-improvement-in-core-depression-and-anxiety-symptoms.aspx

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage ++ +++

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damageHeavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage https://www.news-medical.net/news/20251020/Heavy-drinking-fuels-Alzheimere28099s-disease-by-igniting-brain-inflammation-and-protein-damage.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration. Social and environmental inequality linked to risk of Alzheimer’sSocial and environmental inequality linked to risk of Alzheimer’s https://www.news-medical.net/news/20251020/Social-and-environmental-inequality-linked-to-risk-of-Alzheimere28099s.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare. Study reveals how a microglial mutation increases risk for Alzheimer's disease https://www.news-medical.net/news/20251017/Study-reveals-how-a-microglial-mutation-increases-risk-for-Alzheimers-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function." Living environment may influence dementia markers in the brainLiving environment may influence dementia markers in the brain https://www.news-medical.net/news/20251015/Living-environment-may-influence-dementia-markers-in-the-brain.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 The conditions where you live may influence your brain health and risk for dementia, according to a new study from Wake Forest University School of Medicine Advanced MRI technique reveals early markers of hereditary frontotemporal dementiaAdvanced MRI technique reveals early markers of hereditary frontotemporal dementia https://www.news-medical.net/news/20251016/Advanced-MRI-technique-reveals-early-markers-of-hereditary-frontotemporal-dementia.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=alzheimer_s_disease_newsletter_22_october_2025 An international study led by researchers at Karolinska Institutet in Sweden demonstrates that it is possible to detect subtle changes in the brain and identify early signs of hereditary frontotemporal dementia using advanced brain imaging techniques

Football hits leave lasting brain changes

New MRI research shows that repeated football head impacts can subtly reshape brain structures, offering new clues about chronic traumatic encephalopathy (CTE). https://www.news-medical.net/news/20251030/Football-hits-leave-lasting-brain-changes.aspx

The 2025 report of the Lancet Countdown on health and climate change +...

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01919-1/abstract The 2025 report of the Lancet Countdown on health and climate change provides the most comprehensive assessment to date of the connections between climate change and health, including new metrics which record deaths from extreme heat and wildfire smoke, the coverage of urban blue spaces (rivers, lakes, and coastlines), health adaptation funding, and individual engagement with health and climate change.

The science behind a restful night’s sleep Beth Ann Malow | October 29, 2025

https://geneticliteracyproject.org/2025/10/29/the-science-behind-a-restful-nights-sleep/?mc_cid=322aa6c054&mc_eid=b73600b7ac

Editorial Evidence with a quiet voice The Lancet Planetary Health +++ +... +...

Associations of ambient exposure to benzene, toluene, ethylbenzene, and xylene with daily mortality: a multicountry time-series study in 757 global locations https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(25)00184-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanplh&utm_campaign=update-lanplh&utm_medium=email&_hsenc=p2ANqtz--iLMWXOU4CY-M8iCG9FfvRhfnHej5QtGmoZtpKD4cB7FkUTZDmuO9bw0g3y4ogTrZrJMQCT5EfBCQZbtzf-W2LXqkvbg&_hsmi=387459036&utm_content=387416335&utm_source=hs_email Ageing-related functional and cognitive impairments and cold mortality risk: a longitudinal cohort study in China https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(25)00179-2/fulltext?dgcid=hubspot_update_feature_updatealerts_lanplh&utm_campaign=update-lanplh&utm_medium=email&_hsenc=p2ANqtz-9I8s8i72m-QlNbi5QjtwaZswM7iJHpgdLzUijFxd2N5BDyUtPcA5HCigaFzjGyRZVDGK7VKblgOj9IIB24Qkah9Ne6mQ&_hsmi=387459036&utm_content=387416335&utm_source=hs_email DDT: last mile in the global phase-out of its use for disease vector control? https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(25)00161-5/fulltext?dgcid=hubspot_update_feature_updatealerts_lanplh&utm_campaign=update-lanplh&utm_medium=email&_hsenc=p2ANqtz-8YuwggcPT5MfJ61nU7htdHaAI-fvUgqYm-4H5UXJvv-BVJTwakg_HWvlmYOkdFrF6Q9KQvgkVhEARdScmK1lfDgWwHLQ&_hsmi=387459036&utm_content=387416335&utm_source=hs_email Editorial Evidence with a quiet voice The Lancet Planetary Health https://www.thelancet.com/journals/lanplh/issue/vol9no9/PIIS2542-5196(25)X0010-3 Editorial Climate in court The Lancet Planetary Health https://www.thelancet.com/journals/lanplh/issue/vol9no8/PIIS2542-5196(25)X0009-7

Editorial p803 Lessons from Greek mythology for an AI world The Lancet Psychiatry ++++ +...

The Lancet Psychiatry in conversation with Camilla Rosan on the COS-P perinatal mental health intervention October 07, 2025 • The Lancet Group https://thelancetpsychiatry.buzzsprout.com/1391365/episodes/17892065-camilla-rosan-on-the-cos-p-perinatal-mental-health-intervention?utm_campaign=update-lanpsy&utm_medium=email&_hsenc=p2ANqtz-9pBSXxuzT2kjiiWBrL1hjXOA2AIAslDbtj9p89s8hP3g1B5qFK97G3mM13yTsYF41x91-KXOBs2b26UlpkGwQr7NSDSw&_hsmi=387443168&utm_content=387220155&utm_source=hs_email Lithium as a disease-modifying drug for bipolar disorder Prof Robert M Post, MDa,b ∙ Victor W Li, MDc,d ∙ Prof Michael Berk, MBBChe ∙ Prof Lakshmi N Yatham, MBBS https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00097-5/abstract?utm_campaign=update-lanpsy&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanpsy&_hsenc=p2ANqtz-9632GF18OL271Rwu3eh31nmNvUEg5Ja5xxtc5jLBU0rdPw60X3L5hDZtyKXCcrdbt6qtJjjgGsTrFR9jckbQx8l5n8fQ&_hsmi=387443168&utm_content=387220155&utm_source=hs_email Association between hyperemesis gravidarum and depression: a national register-based controlled study in Finland Eeva Terävä-Utti, MDa,d eeva.l.terava-utti@utu.fi ∙ Miina Nurmi, PhDb ∙ Linda Laitinen, PhDa,e ∙ Tiia Rissanen, MScf ∙ Tarja Järvenpää, PhDc,g ∙ Päivi Polo-Kantola, PhD https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00271-8/abstract?utm_campaign=update-lanpsy&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanpsy&_hsenc=p2ANqtz-_EWOJdg75A6HA9IUfihDmnAKq0JKeWkrwzpbAuivRkGq3YNFcgF8vbtWf_A0bWVAnwf9hVkkh8m4BT-jNYQA9xvRap_g&_hsmi=387443168&utm_content=387220155&utm_source=hs_email Brain structure in schizophrenia: what do we know and what next? https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(25)00172-5/abstract?utm_campaign=update-lanpsy&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanpsy&_hsenc=p2ANqtz-8CiFgvV1Usa6VK46kd2rrlSv0X-irNfeq0o6nGKEB_KYkuT6iMMz_azU1BjMQGBym6MZI24bvp9lmPdUg7ArkhU7bKeg&_hsmi=387443168&utm_content=387220155&utm_source=hs_email Nov 2025 Volume 12Number 11p803-868, e18 Editorial p803 Lessons from Greek mythology for an AI world The Lancet Psychiatry https://www.thelancet.com/journals/lanpsy/issue/vol12no11/PIIS2215-0366(25)X0011-0

European Association for the Study of Diabetes (EASD) 2025 Annual Meeting - September 15 - 19, 2025 Vienna, Austria

https://www.medscape.com/viewcollection/37872?ecd=WNL_conf_Endo_EASD-SPON_251029_MSCPEDIT_etid7829429&uac=148436CN&impID=7829429

European Society for Medical Oncology (ESMO) Annual Meeting 2025 October 17 - 21, 2025 Berlin, Germany and online

https://www.medscape.com/viewcollection/37811

Routine Childhood HPV Vaccinations Demonstrate Striking Long-Term Benefits Maurie Markman, MD October 29, 2025 ++

https://www.medscape.com/viewarticle/routine-childhood-hpv-vaccinations-demonstrate-striking-long-2025a1000pf0 The Health Hype: Social Media Test Ads Push Benefits, Hide Overdiagnosis Risks Maurie Markman, MD https://www.medscape.com/viewarticle/health-hype-social-media-test-ads-push-benefits-hide-2025a1000rf8 October 27, 2025

Patients With a Positive FIT Fail to Get Follow-Up Colonoscopies Nancy A. Melville October 29, 2025 - ++... American College of Gastroenterology (ACG) 2025 Annual Scientific Meeting

https://www.medscape.com/viewarticle/patients-positive-fit-fail-get-follow-colonoscopies-2025a1000tk1 American College of Gastroenterology (ACG) 2025 Annual Scientific Meeting https://www.medscape.com/viewcollection/37913

Social Adversity Tied to Higher Incidence of TNBC Edited by Gargi Mukherjee October 30, 2025

https://www.medscape.com/viewarticle/social-adversity-tied-higher-incidence-tnbc-2025a1000tmz

Europe’s Cancer Divide: Where You Live Still Shapes Survival Cristina Ferrario Medscape Europe October 30, 2025

https://www.medscape.com/viewarticle/europes-cancer-divide-where-you-live-still-shapes-survival-2025a1000tn1

NICE U-Turn Expands Access to Prostate Cancer Drug Joyani Das Medscape UK October 30, 2025

https://www.medscape.com/viewarticle/nice-u-turn-expands-access-prostate-cancer-drug-2025a1000tph In a significant policy reversal, the National Institute for Health and Care Excellence (NICE) has recommended abiraterone for adults with newly diagnosed high-risk metastatic prostate cancer, following a reassessment prompted by the availability of lower-cost generic versions.

Treating Metastatic Colorectal Cancer in the Second Line and Beyond: Oral Therapy Edition Authors: Rahul Gosain, MD, MBA; Rohit Gosain, MD; John Strickler, MD; Chiara Cremolini, MD, PhD

https://www.medscape.org/viewarticle/1003002

Differentiating the TROP-2 ADCs in Breast Cancer Authors: Javier Cortés, MD, PhD; Sara Tolaney, MD, MPH

https://www.medscape.org/viewarticle/1002537?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251029-OUS-HONC-1002537-cta

A field of possibilities for paediatric HIV The Lancet HIV +++... +

Safety and pharmacokinetics of dolutegravir dispersible tablets and oral films in term neonates exposed to HIV in South Africa (PETITE-DTG study): an open-label, randomised, phase 1/2 trial https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00239-5/abstract?dgcid=raven_jbs_etoc_feature_lanhiv A field of possibilities for paediatric HIV The Lancet HIV https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00304-2/fulltext?dgcid=raven_jbs_etoc_email Nov 2025 Volume 12Number 11e737-e810 https://www.thelancet.com/journals/lanhiv/issue/vol12no11/PIIS2352-3018(25)X0011-4 The Academy of Medical Sciences & The Lancet International Health Lecture 2025 https://acmedsci.ac.uk/more/events/IHL-2025?utm_source=lancet&utm_medium=email&utm_campaign=ihl-25 Tuesday 4 November 2025, 15.30 GMT 1 Birdcage Walk, London

miércoles, 29 de octubre de 2025

Four distinct subgroups of PCOS open up for more tailored treatments - polycystic ovary syndrome (PCOS)

https://www.news-medical.net/news/20251029/Four-distinct-subgroups-of-PCOS-open-up-for-more-tailored-treatments.aspx Four distinct subgroups of polycystic ovary syndrome (PCOS) have been identified in an international study published in Nature Medicine by researchers from Karolinska Institutet, among others.

Two analgesic drugs may one day be repurposed as anti-tumor therapies

https://www.news-medical.net/news/20251029/Two-analgesic-drugs-may-one-day-be-repurposed-as-anti-tumor-therapies.aspx Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

Unraveling the secrets of neuronal mechanotransduction

https://www.news-medical.net/news/20251029/Unraveling-the-secrets-of-neuronal-mechanotransduction.aspx

Why Pomegranate Is Good for You: Evidence-Based Insights Into Its Health Benefits

https://www.news-medical.net/health/Why-Pomegranate-Is-Good-for-You-Evidence-Based-Insights-Into-Its-Health-Benefits.aspx Pomegranate’s bioactive compounds such as punicalagins and ellagic acid show strong antioxidant, anti-inflammatory, and cardiovascular benefits, supporting health and longevity. Current research confirms comparable efficacy between pomegranate juice and extracts while emphasizing safe, evidence-based use.

What is Vaginismus? A Guide for Women’s Sexual Health

https://www.news-medical.net/health/What-is-Vaginismus-A-Guide-for-Womene28099s-Sexual-Health.aspx Vaginismus involves involuntary pelvic floor muscle tightening that makes penetration painful or impossible, often linked to fear, anxiety, or past trauma. Effective multidisciplinary treatments, including physical therapy, CBT, and gradual desensitization, achieve success rates of around 80%.

How branding and peer pressure keep kids hooked on energy drinks

https://www.news-medical.net/news/20251028/How-branding-and-peer-pressure-keep-kids-hooked-on-energy-drinks.aspx Despite voluntary age restrictions, a UK study reveals that clever branding, social influence, and online access keep energy and hydration drinks popular among children, underscoring the need for clearer policies and stronger enforcement.

The future of tuberculosis diagnosis: using breath to fight disease spread Researchers are developing new, portable breath analysis tools to diagnose tuberculosis and other diseases, making screenings more accessible in remote areas and beyond.

https://www.drugdiscoverynews.com/sniffing-out-tuberculosis-in-human-breath-16343?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--6f7hBuFNi3AKLCltGo4LXIaZ2hWVEIKbrGAILJPlJ8YN0sDiiz0F2svI83MFGDn3u1u3ClTbSemPFJT1SQu-ukgN6wQ&_hsmi=387404680&utm_content=387404680&utm_source=hs_email

Transforming oral medications into inhaled therapies to treat the lungs Pulmonary fibrosis patients have long suffered through side effects from their drugs. That could change with the potential for new inhaled versions in clinical trials.

https://www.drugdiscoverynews.com/transforming-oral-medications-into-inhaled-therapies-to-treat-the-lungs-16767

FDA approves first treatment for non-cystic fibrosis bronchiectasis First DPP1 inhibitor drug milestone marks a long-awaited breakthrough for NCFB patients.

https://www.drugdiscoverynews.com/fda-approves-first-treatment-for-non-cystic-fibrosis-bronchiectasis-16571?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9huX5GJ5dXrscTFQ29NzSj3wqfq3zTekUu-wVCeT9VRfvY-c6H9SVh_idDNM2WMsfloIvZwqjDhZ_qXZkY5_hd_WCo-w&_hsmi=387404680&utm_content=387404680&utm_source=hs_email

Editorial p897 World Heart Day: diabetes and cardiovascular risk The Lancet Diabetes & Endocrinology +++ +... +...

Once-weekly semaglutide 7·2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00226-8/abstract?utm_campaign=update-landia&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_landia&_hsenc=p2ANqtz--5iZS_-Nr1t8mxWNMnOZDkeogxiRxjoWnZ-jq9dY4ui8EVOmK-XH9Co15jIhOzxmuq0b6r1pwggMYyk-lcA8I-l8mFkw&_hsmi=387259193&utm_content=387001941&utm_source=hs_email Efficacy and safety of monlunabant in adults with obesity and metabolic syndrome: a double-blind, randomised, placebo-controlled, phase 2a trial https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00216-5/abstract?utm_campaign=update-landia&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_landia&_hsenc=p2ANqtz-_gNS7ek3C1D9rqqgJarEoYfr7es7lAowxvz57q3WyK3F35oNMB0X3W5h8dTmjuzvmyTsW4bEvkoc268zAal9hUpldlVQ&_hsmi=387259193&utm_content=387001941&utm_source=hs_email Global, regional, and national cascades of diabetes care, 2000–23: a systematic review and modelling analysis using findings from the Global Burden of Disease Study https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00217-7/abstract?utm_campaign=update-landia&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_landia&_hsenc=p2ANqtz--pegZPYONcuOOb9uKXQemdlntOL8Lo3xC-ELOMA1n_zr7yO7AHeMeKDdbLWYE_IHvAzaK6VmHPqgY9e4hzCnyVc5zN1Q&_hsmi=387259193&utm_content=387001941&utm_source=hs_email The Lancet Summit: shaping the future of diabetes prevention Nov 30–Dec 2, 2026 | Sitges, Spain https://thelancetsummit.com/diabetes-prevention/index.html?utm_campaign=update-landia&utm_medium=email&_hsenc=p2ANqtz-8FkP8ordpzNdmbiuA1aaii4E2BeKJHuWiNC0J7bYJQ-zk-xs6rUzyMJCeXo04668zmb3PG5NlS4SkUIOV-FJVzjcogMw&_hsmi=387259193&utm_content=387001941&utm_source=hs_email Nov 2025 Volume 13Number 11p897-986, e14 https://www.thelancet.com/journals/landia/issue/vol13no11/PIIS2213-8587(25)X0011-5 Editorial p897 World Heart Day: diabetes and cardiovascular risk The Lancet Diabetes & Endocrinology

Editorial p893 Essential medicines for neurological disorders: updates, rejections, and the road ahead The Lancet Neurology +++ +...

High-sensitivity C-reactive protein, LDL cholesterol, lipoprotein(a) and 30-year risk of stroke in healthy women: a prospective, longitudinal cohort study https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00306-0/abstract?utm_campaign=update-laneur&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_laneur&_hsenc=p2ANqtz--XowdCDoSgAEfDjsPUVEKAknVJcJG-rX4yKfKWhj35mKnyHoEcsz-nylo-RcPDM8gTGFl9UOnXz-rlT2v432VrcKYVrg&_hsmi=387249641&utm_content=387002595&utm_source=hs_email The temporal order of genetic, environmental, and pathological risk factors in Parkinson's disease: paving the way to prevention https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00271-6/abstract?utm_campaign=update-laneur&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_laneur&_hsenc=p2ANqtz-8iikd7BJmOKlCauCjc6TZ2-Ws5lEV3sotvQmyLotT5SNTZLvrBRvf7xOpO7XE6TMlWMWaj6Oa6IBFzoWVFnXzamnXrtQ&_hsmi=387249641&utm_content=387002595&utm_source=hs_email Advances in screening and management of unruptured intracranial aneurysms https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00265-0/abstract?utm_campaign=update-laneur&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_laneur&_hsenc=p2ANqtz-8XlxAJ1dJZ8ybuBk_vxHQk6nD5SLEhw6ulGVcdi5mGTNFfD6dLkZwrf1FDiIuCL9shSVOMrZIwUCwtXDqJCfraAyPoRA&_hsmi=387249641&utm_content=387002595&utm_source=hs_email Editorial p893 Essential medicines for neurological disorders: updates, rejections, and the road ahead The Lancet Neurology https://www.thelancet.com/journals/laneur/issue/vol24no11/PIIS1474-4422(25)X0011-9

HER2-Positive Gastroesophageal Adenocarcinoma and Biliary Tract Cancer: Updates and Insights Authors: Haley Ellis, MD; Steven Maron, MD, MSc

https://www.medscape.org/viewarticle/her2-positive-gastroesophageal-adenocarcinoma-and-biliary-2025a1000sr3?page=1&sso=true&impID=7832153&uac=148436CN&src=wnl_tpal_251028_mscpedu

The Keratinocyte Carcinoma Talk Show Authors: ​David Miller, MD, PhD; Vishal A. Patel, MD; Kevin Emerick, MD; Anokhi Jambusaria-Pahlajani, MD, MSCE

https://www.medscape.org/viewarticle/1003021?sso=true&impID=7832153&uac=148436CN&src=wnl_tpal_251028_mscpedu

Human Gene Therapy: Sarepta Pauses, then Resumes, Shipments of DMD Gene Therapy

https://www.liebertpub.com/toc/hum/36/19-20

Deep Intronic SVA_E Retrotransposition as a Novel Factor in Canavan Disease Pathogenesis

https://www.liebertpub.com/doi/10.1089/hum.2025.006?utm_campaign=MAL_HUM&utm_medium=email&_hsenc=p2ANqtz-9NhCc_06E_5HnZH2vXJFFLzaaZ97OyJCTtko2Oi2tk4rTkXt6FcJlyb-cMXAYaAYvAz5CSkRMtB0d_auUkm9FMs1qMEQ&_hsmi=387089561&utm_content=387089561&utm_source=hs_email

Trojan Horse-Like Vehicles for CRISPR-Cas Delivery: Engineering Extracellular Vesicles and Virus-Like Particles for Precision Gene Editing in Cystic Fibrosis

https://www.liebertpub.com/doi/10.1089/hum.2024.258?utm_campaign=MAL_HUM&utm_medium=email&_hsenc=p2ANqtz-9pkkO_kz9VdXy2V7zb4VgPmjHA6LRJbqHKE5VR1RaGNu5nC8dkjYEBl0qFgrseTVMVEsICIRINc64lhGZ1rkeneNZiaQ&_hsmi=387089561&utm_content=387089561&utm_source=hs_email

Targeting Amyotrophic Lateral Sclerosis with Gene Therapy: From Silencing Genes to Enhancing Neuroprotection

https://www.liebertpub.com/doi/10.1177/10430342251372898?utm_campaign=MAL_HUM&utm_medium=email&_hsenc=p2ANqtz-_OXq-9epHhGrmZG6WuOCt2gWNRv-76-PgeYVjsYv0YSwQ3gJJSnjGEttgG83lUwbj3BP4IFf9_snpRhsrIjydIFG_uXQ&_hsmi=387089561&utm_content=387089561&utm_source=hs_email

NF-1 Associated Plexiform Neurofibromas in Adults: Which Patients Could Benefit From Emerging Systemic Therapies? Authors: Andrea Gross, MD; João Passos, MD

https://www.medscape.org/viewarticle/managing-patients-hr-her2-ebc-assess-your-knowledge-2025a1000ier?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251028-OUS-HONC-managing-patients-hr-her2-ebc-assess-your-knowledge-2025a1000ier-cta

Managing Patients With HR+/HER2- EBC: Assess Your Knowledge Authors: Reshma Mahtani, DO

https://www.medscape.org/viewarticle/managing-patients-hr-her2-ebc-assess-your-knowledge-2025a1000ier?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251028-OUS-HONC-managing-patients-hr-her2-ebc-assess-your-knowledge-2025a1000ier-cta

FDA approves revumenib for relapsed or refractory acute myeloid leukemia with a susceptible NPM1 mutation

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-revumenib-relapsed-or-refractory-acute-myeloid-leukemia-susceptible-npm1-mutation

martes, 28 de octubre de 2025

Clinically significant valvular heart disease vastly underdiagnosed in U.S. elders

https://www.news-medical.net/news/20251028/Clinically-significant-valvular-heart-disease-vastly-underdiagnosed-in-US-elders.aspx

Air pollution, even below EPA guidelines, increases breast cancer risk

https://www.news-medical.net/news/20251028/Air-pollution-even-below-EPA-guidelines-increases-breast-cancer-risk.aspx

Study links poor sleep to adverse health outcomes in seniors

https://www.news-medical.net/news/20251028/Study-links-poor-sleep-to-adverse-health-outcomes-in-seniors.aspx

Mediterranean-style diets improve pelvic floor function and sexual health, review finds ++++ ++++

Mediterranean-style diets improve pelvic floor function and sexual health, review finds https://www.news-medical.net/news/20251019/Mediterranean-style-diets-improve-pelvic-floor-function-and-sexual-health-review-finds.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Mediterranean-style diets improve pelvic floor function and sexual health, review findsThis systematic review and meta-analysis of 31 studies reveals that healthy, anti-inflammatory dietary patterns, particularly the Mediterranean and DASH diets, are linked to improved sexual function and reduced incontinence symptoms in pelvic floor dysfunction. Low-fat vegan diet shown to reduce insulin use and costs in type 1 diabetes https://www.news-medical.net/news/20251015/Low-fat-vegan-diet-shown-to-reduce-insulin-use-and-costs-in-type-1-diabetes.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Low-fat vegan diet shown to reduce insulin use and costs in type 1 diabetesA low-fat vegan diet that doesn't limit calories or carbohydrates could help people with type 1 diabetes reduce insulin use and insulin costs, according to new research by the Physicians Committee for Responsible Medicine published in BMC Nutrition. Food allergy diagnoses plummet after guideline implementation https://www.news-medical.net/news/20251021/Food-allergy-diagnoses-plummet-after-guideline-implementation.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Food allergy diagnoses plummet after guideline implementationPeanuts represent one of the most common causes of immunoglobulin E (IgE)-mediated, or anaphylactic, food allergies in children, yet a landmark study found that early introduction of peanut to infants may lower their risk of developing this allergy. Ganoderma lucidum protects against liver damage from high-fat diets https://www.news-medical.net/news/20251016/Ganoderma-lucidum-protects-against-liver-damage-from-high-fat-diets.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Ganoderma lucidum protects against liver damage from high-fat dietsA long-term high-fat diet (HFD) exerts lipotoxic effects on multiple organs, particularly the liver, leading to metabolic diseases. Neighborhood environments can influence a child's risk of developing type 2 diabetes https://www.news-medical.net/news/20251021/Neighborhood-environments-can-influence-a-childs-risk-of-developing-type-2-diabetes.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Neighborhood environments can influence a child's risk of developing type 2 diabetesType 2 diabetes (T2D), once considered an adult-onset disease, is increasing at alarming rates in children and adolescents. Before the mid-1990s, just 1% to 2% of youth with diabetes had T2D. Can fitness apps and wearables make children healthier? This study says yes - partly https://www.news-medical.net/news/20251020/Can-fitness-apps-and-wearables-make-children-healthier-This-study-says-yes-partly.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Can fitness apps and wearables make children healthier? This study says yes - partlyDigital health tools such as apps, wearables, and web platforms can modestly improve children’s physical activity, diet, and weight outcomes. Shorter programs boost activity, while longer ones better support weight management, though effects on sleep and sedentary time remain unclear. Exercise can mitigate depression-like behaviors induced by high-fat, high-sugar diets https://www.news-medical.net/news/20251021/Exercise-can-mitigate-depression-like-behaviors-induced-by-high-fat-high-sugar-diets.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Exercise can mitigate depression-like behaviors induced by high-fat, high-sugar dietsResearchers led by Professor Yvonne Nolan at University College Cork have identified specific metabolic pathways through which exercise counteracts the negative behavioral effects of consuming a Western-style cafeteria diet. Best sources of selenium: Benefits, foods, and daily requirements https://www.news-medical.net/health/Best-Sources-of-Selenium-Benefits-Foods-and-Daily-Requirements.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Best sources of selenium: Benefits, foods, and daily requirementsEat smart for your thyroid and immunity: learn which foods pack selenium safely, how much you really need, and why moderation outperforms megadoses.

AI system watches kids eat to reveal how bite habits predict obesity risk +++++

AI system watches kids eat to reveal how bite habits predict obesity risk https://www.news-medical.net/news/20251021/AI-system-watches-kids-eat-to-reveal-how-bite-habits-predict-obesity-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 AI system watches kids eat to reveal how bite habits predict obesity riskThis study introduces ByteTrack, an AI system that analyzes bite behavior in children, offering new strategies for obesity prevention at the dinner table. What happens when microplastics reach the testes? Study shows autophagy and cell loss https://www.news-medical.net/news/20251015/What-happens-when-microplastics-reach-the-testes-Study-shows-autophagy-and-cell-loss.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 What happens when microplastics reach the testes? Study shows autophagy and cell lossResearchers found that microplastics from everyday plastic tableware accumulate in human semen and, although not linked to semen quality in the full cohort, were associated with altered sperm parameters in specific subgroups. Experimental models confirmed that 50 nm polystyrene particles trigger autophagy and apoptosis via the FOXA1/MAP3K1/p38 pathway, impairing sperm structure and function. Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults https://www.news-medical.net/news/20251021/Can-strawberries-help-prevent-diabetes-New-trial-shows-promising-results-in-prediabetic-adults.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adultsDaily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health. Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests https://www.news-medical.net/news/20251019/Low-calorie-diets-linked-to-higher-psoriatic-arthritis-risk-genetic-study-suggests.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggestsThis Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease. Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health https://www.news-medical.net/news/20251017/Review-reveals-how-paternal-lifestyle-shapes-sperm-epigenetics-and-offspring-health.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Review reveals how paternal lifestyle shapes sperm epigenetics and offspring healthA new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

Which foods and supplements really ease chronic constipation? +++

Which foods and supplements really ease chronic constipation? https://www.news-medical.net/news/20251016/Which-foods-and-supplements-really-ease-chronic-constipation.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Backed by four major reviews, the BDA’s first-ever constipation guidelines separate science from myth, highlighting psyllium, kiwifruit, and magnesium oxide as proven allies for better gut health. Does eating watermelon lower blood pressure? A new review explores whether watermelon’s naturally concentrated L-citrulline, especially from the rind, could offer a food-based route to support blood pressure and vascular function, challenging the need for synthetic arginine supplements. https://www.news-medical.net/news/20251015/Does-eating-watermelon-lower-blood-pressure.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025 Front-of-package health claims don’t reflect true nutrition Researchers analyzing nearly 600 grocery items found that flashy front-label claims—like “heart healthy” or “keto-friendly,” often fail to match real nutrition, urging doctors and shoppers to focus on what’s inside the Nutrition Facts panel instead. https://www.news-medical.net/news/20251017/Front-of-package-health-claims-done28099t-reflect-true-nutrition.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025

BD² expands global effort to examine the key mechanisms of bipolar disorder

https://www.news-medical.net/news/20251028/BDc2b2-expands-global-effort-to-examine-the-key-mechanisms-of-bipolar-disorder.aspx

Obesity’s health risks shift with age and sex, new genetic study reveals

A massive UK Biobank analysis reveals that the health risks of obesity shift over time, peaking at different ages for men and women, and that midlife preventive care may blunt its cardiovascular damage. https://www.news-medical.net/news/20251027/Obesitye28099s-health-risks-shift-with-age-and-sex-new-genetic-study-reveals.aspx

Why the first 1,000 days matter most in preventing childhood obesity

A major European review finds that childhood obesity prevention must begin before conception, addressing both parents’ health and the social systems shaping family behaviours. https://www.news-medical.net/news/20251020/Why-the-first-1000-days-matter-most-in-preventing-childhood-obesity.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=nutrition_newsletter_23_october_2025

International funding for cancer care: a shared responsibility The Lancet Oncology +++ +...

Clinical potential of whole-genome data linked to mortality statistics in patients with breast cancer in the UK: a retrospective analysis https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00400-0/fulltext?dgcid=raven_jbs_etoc_feature_lanonc Artificial Intelligence for Response Assessment in Pediatric Neuro-Oncology (AI-RAPNO), part 1: review of the current state of the art https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00484-X/abstract?dgcid=raven_jbs_etoc_feature_lanonc International funding for cancer care: a shared responsibility The Lancet Oncology https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00620-5/fulltext?dgcid=raven_jbs_etoc_email Nov 2025 Volume 26Number 11p1393-1510, e571-e619 https://www.thelancet.com/journals/lanonc/issue/vol26no11/PIIS1470-2045(25)X0011-5

Mental health: a public health crisis unfolding The Lancet Public Health ++...

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00261-0/fulltext?dgcid=raven_jbs_etoc_email Nov 2025 Volume 10Number 11e890-e1005 https://www.thelancet.com/journals/lanpub/issue/vol10no11/PIIS2468-2667(25)X0011-6

Innate immunity regulation of brain health: a webinar from The Lancet Group and Cell Press Thursday, 20/11/2025 · 10:00 Atlantic Time (Canada) (GMT -4:00)

https://www.bigmarker.com/lancet-webinars/innate-immunity-regulation-of-brain-health-a-webinar-from-the-lancet-group-and-cell-press?utm_bmcr_source=hubspot_email_reg1_tlcp_neuroimmunology&_hsmi=387073413&_hsenc=p2ANqtz-8X8X2uIDbDc1dqyI0xLyo5qu1Ymdahfg8jYIEUZ2Y3qHvV7ixUxWG7QSLuVCCUryDp9SDYqZ63_SHd4oQTKxa7B3bUtw&hsCtaAttrib=197536830229

Polygenic Risk Score Predicts Outcomes After DCIS, LCIS Ernie Mundell October 28, 2025

https://www.medscape.com/viewarticle/polygenic-risk-score-predicts-outcomes-after-dcis-lcis-2025a1000tcr

Pluvicto in First-line Hormone-Sensitive Prostate Cancer? Megan Brooks October 28, 2025

https://www.medscape.com/viewarticle/pluvicto-first-line-hormone-sensitive-prostate-cancer-2025a1000tbk

Targeted T-cell Therapy Beneficial in Rare Form of Melanoma Liam Davenport October 28, 2025

https://www.medscape.com/viewarticle/targeted-t-cell-therapy-beneficial-rare-form-melanoma-2025a1000tcu

Geographic Clusters Show Uneven Cancer Screening in the US Edited by Gargi Mukherjee October 28, 2025

https://www.medscape.com/viewarticle/geographic-clusters-show-uneven-cancer-screening-us-2025a1000td5

Oxford Trial Tests AI to Find Cancers in Dense Breasts Dr Sheena Meredith

https://www.medscape.com/viewarticle/oxford-trial-tests-ai-find-cancers-dense-breasts-2025a1000tdg

HER2-Positive Gastroesophageal Adenocarcinoma and Biliary Tract Cancer: Updates and Insights Authors: Haley Ellis, MD; Steven Maron, MD, MSc

https://www.medscape.org/viewarticle/her2-positive-gastroesophageal-adenocarcinoma-and-biliary-2025a1000sr3?page=1

Contemporary Glioma Care: Innovation, Collaboration, and Transformation

Contemporary Glioma Care: Innovation, Collaboration, and Transformation Diffuse gliomas of lower grade (LGGs) present complex challenges in neuro-oncology. Recent advances in molecular profiling have revolutionized our understanding of these tumors, primarily IDH-mutated astrocytomas and oligodendrogliomas, leading to more- https://www.medscape.org/oncology?_gl=1*1bjf2l0*_gcl_au*MTgwODMwNDA1NS4xNzU4Mjg3OTM2LjI1NjgxOTg3LjE3NjE2NTg3MzQuMTc2MTY1ODczMw..

Highlights from the Annual Neurosurgical Conference: New Standards in Diffuse Lower-Grade Glioma Authors: Mitchel S. Berger, MD; Macarena de la Fuente, MD; Michael Lim, MD

https://www.medscape.org/viewarticle/1002598?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251027-OUS-HONC-1002598-cta

lunes, 27 de octubre de 2025

Saving Your Voice as You Age By Ivanhoe Broadcast News on October 7, 2025

https://www.ivanhoe.com/family-health/saving-your-voice-as-you-age/

Plastic’s Toxic Effects on the Heart By Ivanhoe Broadcast News on October 8, 2025

https://www.ivanhoe.com/family-health/plastics-toxic-effects-on-the-heart/

Strategies To Slow Parkinson’s By Ivanhoe Broadcast News on October 9, 2025

https://www.ivanhoe.com/family-health/strategies-to-slow-parkinsons/

isaac: New, Easier Way to Monitor Diabetes By Ivanhoe Broadcast News on October 10, 2025

https://www.ivanhoe.com/family-health/isaac-new-easier-way-to-monitor-diabetes/

Green Teens: Protecting the Future By Ivanhoe Broadcast News on October 26, 2024

https://www.ivanhoe.com/positive-parenting/green-teens-protecting-the-future/

Nurturing Nature’s Next Generation By Ivanhoe Broadcast News on October 27, 2024

https://www.ivanhoe.com/positive-parenting/nurturing-natures-next-generation/

Brace For Impact! Keep Your Family Safe in The Storm By Ivanhoe Broadcast News on October 27, 2024

https://www.ivanhoe.com/positive-parenting/brace-for-impact-keep-your-family-safe-in-the-storm/

Vitamin P: The Power of Pleasure Foods! By Ivanhoe Broadcast News on October 28, 2025

https://www.ivanhoe.com/?p=36212&preview=1&_ppp=dbd3fbf9c6

Stem Stereotypes: Gender Bias Still Impacting Young Girls?! By Ivanhoe Broadcast News on October 27, 2025

https://www.ivanhoe.com/smart-living/stem-stereotypes-gender-bias-still-impacting-young-girls/

Popular bubble tea may contain concerning levels of heavy metal, investigation finds By Angelica Stabile Fox News Published October 24, 2025 11:50am EDT

Popular bubble tea may contain concerning levels of heavy metal, investigation finds Three out of four boba samples contained more than 50% of concerning lead levels in one serving Angelica Stabile By Angelica Stabile Fox News Published October 24, 2025 11:50am EDT https://www.foxnews.com/health/popular-bubble-tea-may-contain-concerning-levels-heavy-metal-investigation-finds

Kim Kardashian’s brain aneurysm scare: Doctors reveal warning signs to never ignore By Angelica Stabile Fox News Published October 25, 2025 1:53pm EDT

Kim Kardashian’s brain aneurysm scare: Doctors reveal warning signs to never ignore Neurosurgery expert says condition affects women more than men Angelica Stabile By Angelica Stabile Fox News Published October 25, 2025 1:53pm EDT https://www.foxnews.com/health/kim-kardashian-brain-aneurysm-scare-doctors-reveal-warning-signs-never-ignore

Scientists uncover how some 80-year-olds have the memory of 50-year-olds By Melissa Rudy Fox News Published October 25, 2025 11:00am EDT

Scientists uncover how some 80-year-olds have the memory of 50-year-olds 'SuperAgers' share common traits that give them greater cognitive resilience Melissa Rudy By Melissa Rudy Fox News Published October 25, 2025 11:00am EDT https://www.foxnews.com/health/scientists-uncover-how-some-80-year-olds-have-memory-50-year-olds

Shingles vaccine connected to ‘exciting’ health benefits in large study By Amy McGorry Fox News Published October 27, 2025 7:00am EDT

Shingles vaccine connected to ‘exciting’ health benefits in large study Vaccine may cut risk of dementia by nearly a half and lower risk of heart disease by a quarter, experts say By Amy McGorry Fox News Published October 27, 2025 7:00am EDT https://www.foxnews.com/health/shingles-vaccine-connected-exciting-health-benefits-large-study

A healthy breast microbiome may help prevent cancer Tamoxifen and a Mediterranean diet promoted bacterial communities that suppress breast tumor growth.

https://www.drugdiscoverynews.com/a-healthy-breast-microbiome-may-help-prevent-cancer-16278?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9o2io0LPBwglYwI5hRUGsWc8rzx1y4LAYyAkSnyvcauOODv-Ofkz0TyjZd2ewiR3IA3qGppox6xRzmZdRLHghCnZJQBQ&_hsmi=387021267&utm_content=387021267&utm_source=hs_email

Drug treatment sparks communal behaviors in gut microbes Gut microbes can protect or sensitize each other to drugs, even to non-antibiotics.

https://www.drugdiscoverynews.com/drug-treatment-sparks-communal-behaviors-in-gut-microbes-16155?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--243hxdWgooYKFyTTnCiZ8Hktc4lbr4eROmO1aRKcGybs-YAz_4uGpttVgpapciwsHlg0yK901KX1Jji-7iq71FADiDg&_hsmi=387021267&utm_content=387021267&utm_source=hs_email

What Drives Lung Cancer in Nonsmokers? Edited by Gargi Mukherjee October 27, 2025

https://www.medscape.com/viewarticle/what-drives-lung-cancer-nonsmokers-2025a1000t7l

Two ADCs Offer More Hope for Patients With Advanced TNBC Liam Davenport October 27, 2025

https://www.medscape.com/viewarticle/two-adcs-offer-more-hope-patients-advanced-tnbc-2025a1000t82

Revumenib Picks Up Indication for NPM1-Mutated R/R AML M. Alexander Otto, PA, MMSc October 27, 2025

https://www.medscape.com/viewarticle/revumenib-picks-indication-npm1-mutated-r-r-aml-2025a1000t6a

European Society for Medical Oncology (ESMO) Annual Meeting 2025

https://www.medscape.com/viewcollection/37811 Lenvatinib Disappoints in Metastatic Esophageal Cancer Trial Kate Johnson https://www.medscape.com/viewarticle/lenvatinib-disappoints-metastatic-esophageal-cancer-trial-2025a1000t4o October 27, 2025

Conditioning Regimens for HSCT in AML/MDS: Importance of Individualization in Your Adult Patients Authors: Domenico Russo, MD, PhD; Daniele Avenoso, MD, PhD; Matthias Stelljes, MD

https://www.medscape.org/viewarticle/1002516?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_251026-OUS-HONC-1002516-cta

Breast Cancer: 5 Things to Know | Innovations in BC Side Effect Management ++++ ++++ ++

Breast cancer is the most common cancer in women worldwide. In October, special attention is paid worldwide to raising awareness about breast cancer, its detection, and its treatment. Treatment & Clinical Management Can Heart Drug Prevent Cardiotoxicity in Breast Cancer Care? https://www.medscape.com/viewarticle/can-sacubitril-valsartan-prevent-cardiac-dysfunction-2025a1000nel?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Who Needs Axillary Dissection After Breast Cancer Treatment? https://www.medscape.com/viewarticle/who-needs-axillary-dissection-after-breast-cancer-treatment-2025a1000nn4?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 5 Things to Know https://www.medscape.com/viewarticle/breast-cancer-carcinoma-new-treatment-diagnosis-oncology-2025a1000msr?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Is Lower-Dose Ribociclib Equally Effective in Breast Cancer? https://www.medscape.com/viewarticle/lower-dose-ribociclib-equally-effective-breast-cancer-2025a1000pnx?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Supportive Care, Risks & Survivorship Frailty Ups Surgery Risks for Older Women With Breast Cancer https://www.medscape.com/viewarticle/frailty-ups-surgery-risks-older-women-breast-cancer-2025a1000oig?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Phone-Based Program Boosts Weight Loss in Breast Cancer https://www.medscape.com/viewarticle/phone-based-program-boosts-weight-loss-breast-cancer-2025a1000m38?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Innovations in Breast Cancer Side Effect Management https://www.medscape.com/viewarticle/managing-breast-cancer-treatment-side-effects-2025a1000mwy?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Vitamin B12 Cuts Risk for Chemotherapy Hand-Foot Syndrome https://www.medscape.com/viewarticle/vitamin-b12-cuts-risk-chemotherapy-hand-foot-syndrome-2025a1000pns?ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 ✨Medscape AI: Top Searched Queries Breast Cancer Screening: Average-Risk Women 40 Vs 50 https://www.medscape.com/ai-search?query=Breast%20Cancer%20Screening%20Recommendations%20Average-Risk%20Women%2040%20Vs%2050&&ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021 Latest Breast Cancer Guideline Updates 2025 https://www.medscape.com/ai-search?query=Latest%20Breast%20Cancer%20Guideline%20Updates%202025&&ecd=mkm_ret_251027_mscpmrk-OUS_InFocus_etid7822021&uac=148436CN&impID=7822021

domingo, 26 de octubre de 2025

Mitochondria and lysosomes work together to control regulatory T cell activation

https://www.news-medical.net/news/20251024/Mitochondria-and-lysosomes-work-together-to-control-regulatory-T-cell-activation.aspx

Eliminating cockroaches drastically reduces household allergens and endotoxins

https://www.news-medical.net/news/20251024/Eliminating-cockroaches-drastically-reduces-household-allergens-and-endotoxins.aspx

Optimizing Management of NF1-Associated Plexiform Neurofibromas: Expert Multidisciplinary Team Discussions Authors: Judith Eelloo, RGN, RSCN, MPhil; Darren Hargrave, MD; Zhichao Wang, MD, MPH; Kaleb Yohay, MD

https://www.medscape.org/viewarticle/1001627_sidebar9

Recognizing Subtle Disability Worsening in Multiple Sclerosis (Part 1): The Role of Smoldering Neuroinflammation Authors: Laura Airas, MD, PhD; Martina Absinta, MD, PhD; Benjamin M. Greenberg, MD, MHS

https://www.medscape.org/viewarticle/1002761_sidebar9

Hormone Receptor-Positive, HER2-Negative Early Breast Cancer: The Adjuvant Clinical Trial Populations Explained Authors: Erika Hamilton, MD; Nadia Harbeck, MD, PhD

https://www.medscape.org/viewarticle/1002403_sidebar12?sso=true&uac=148436CN&ecd=mkm_ret_251026_mscpmrk-ES_CME_etid7795962&impID=7795962

Virtual Simulations: Managing the Patient With HR+/HER2- Early Breast Cancer Through a Multidisciplinary Approach Authors: Manali Bhave, MD; Jane Meisel, MD

https://www.medscape.org/viewarticle/1002474_sidebar5?sso=true&uac=148436CN&ecd=mkm_ret_251026_mscpmrk-ES_CME_etid7795962&impID=7795962

The Patient With HR+/HER2- Early Breast Cancer: The Importance of Communication at All Stages of Management Authors: Shaheenah Dawood, MBBCh, MPH, FACP

https://www.medscape.org/viewarticle/1002462_sidebar11?sso=true&uac=148436CN&ecd=mkm_ret_251026_mscpmrk-ES_CME_etid7795962&impID=7795962

Advanced Prostate Cancer

https://www.medscape.org/sites/advances/advanced-prostate-cancer

Comprehensive and Personalized Approach to Managing mHSPC: Fitting the Right Pieces for Each Patient Authors: Fred Saad, MD, FRCS; Elena Castro, MD, PhD

https://www.medscape.org/viewarticle/1002043_sidebar7?sso=true&uac=148436CN&ecd=mkm_ret_251026_mscpmrk-ES_CME_etid7795962&impID=7795962

Moving the Needle in ER-Positive/HER2-Negative Metastatic Breast Cancer: Exploring SERD Strategies to Optimize Outcomes Authors: Nadia Harbeck, MD, PhD; Aditya Bardia, MD, MPH, FASCO; Shaheenah Dawood, MBBCh, MPH, FACP; William J. Gradishar, MD, FASCO

https://www.medscape.org/viewarticle/1002163_sidebar5?sso=true&uac=148436CN&ecd=mkm_ret_251026_mscpmrk-ES_CME_etid7795962&impID=7795962

Guiding Our Patient's Path: Managing First Relapse in Diffuse Large B-Cell Lymphoma Outside of CAR Ts Authors: Wendy Osborne, MBBS (Hons), MRCP, FRCPath; Natacha Bolaños; Gareth Gregory, MBBS, PhD; Gilles Salles, MD, PhD

https://www.medscape.org/viewarticle/1002120_sidebar9?sso=true&uac=148436CN&ecd=mkm_ret_251026_mscpmrk-ES_CME_etid7795962&impID=7795962

Highlights From the Annual Oncology Meeting: Clinical Integration of Therapeutic Innovations in Glioma Authors: Matthias Preusser, MD; Manmeet S. Ahluwalia, MD, MBA, FASCO; L. Nicolas Gonzalez Castro, MD, PhD; Jeremy Pivor

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Illuminating the Path: New Insights in EGFR-Mutated Advanced NSCLC Authors: Antonio Passaro, MD, PhD; Enriqueta Felip, MD

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Expert Perspectives on the Latest Clinical Trial Updates in HR-Positive, HER2-Negative Early Breast Cancer Authors: Stephen R. D. Johnston, MA, FRCP, PhD; Priya Rastogi, MD

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Is AAV gene therapy at a turning point? After a decade of promise, AAV therapies are now confronting economic, clinical, and regulatory hurdles.

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Weekly Rundown: Galapagos to discontinue cell therapy unit Multibillion dollar oncology deals, first-in-class wins, AI scientists, and more led the news this week.

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Editorial p801 NINDS at the forefront of epilepsy research for 75 years The Lancet Neurology + +(¡!) + +...

Candesartan versus placebo for migraine prevention in patients with episodic migraine: a randomised, triple-blind, placebo-controlled, phase 2 trial https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00269-8/abstract?utm_campaign=infocusalerts-neurology&utm_medium=email&dgcid=hubspot_email_infocusalerts-neurology_feature&_hsenc=p2ANqtz-_x21S2JeJ_ykFn_JuQCI3G_HsJd9O_oqtcs-tYXbU6iLlV2cjTXVt6ZVU3vQeZFMtoub4OL1r5M6hhGJLIKnSF_fnVoQ&_hsmi=386748627&utm_content=386532796&utm_source=hs_email Innate immunity regulation of brain health: a webinar from The Lancet Group and Cell Press About Innate immunity is the body's first line of defence against infections and injury. In the central nervous system, it is crucial for protecting against pathogens and clearing damaged tissue, while maintaining neural function. However, chronic innate immune activation can contribute to neuroinflammation. This joint webinar between The Lancet Group and Cell Press will: Provide an accessible overview of the importance of innate immunity in the development of neurological diseases, including interferonopathies, multiple sclerosis, and neurodegenerative diseases. Review potential therapeutic targets to protect neurons from inflammation-induced neurodegeneration in multiple sclerosis. Discuss common features of innate immunity across neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, and the neuroimmune interactions that can propagate neurotoxicity. Examine the triggers of these mechanisms in neurons and glia. When Thursday, 20/11/2025 · 10:00 Atlantic Time (Canada) (GMT -4:00) https://www.bigmarker.com/lancet-webinars/innate-immunity-regulation-of-brain-health-a-webinar-from-the-lancet-group-and-cell-press?utm_bmcr_source=hubspot_email_infocusalerts-neurology&_hsenc=p2ANqtz-9TrFzB7s7F8g-5QluT7AFREqo7OuJaboO01tGq6lVxu25otcBkpwv79uS6Bv6CWGz6G9Y_nJYqXHde2wOoFHb4_yBHGw&_hsmi=386748627 Shiv Saidha on recent updates in the diagnosis of multiple sclerosis September 17, 2025 • The Lancet Group https://thelancetneurology.buzzsprout.com/1391383/episodes/17853972-shiv-saidha-on-recent-updates-in-the-diagnosis-of-multiple-sclerosis?utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9JEkUxTpF5yUcjCZtfRiMR-BCPz8AbQuQ-m2f16kd38XrDBNttKJiHjq06Cqhs1zRKL66iWS8AhF9TpBGqLc78s3mdKw&_hsmi=386748627&utm_content=386532796&utm_source=hs_email Editorial p801 NINDS at the forefront of epilepsy research for 75 years The Lancet Neurology https://www.thelancet.com/journals/laneur/issue/vol24no10/PIIS1474-4422(25)X0010-7

Targeted Therapies for NSCLC: Where Are We Today? Authors: Solange Peters, MD, PhD; Benjamin J. Solomon, MBBS, PhD

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Think You Know IDH-Mutant Glioma? Test Your Clinical Expertise on the Latest Advances Authors: Patrick Y. Wen, MD

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