Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Other novel compounds with Mpro inhibitory activity have also been claimed to have antiviral activity. These include ebselen, disulfiram, tideglusib, carmofur, shikonin, and PX-12. A new research paper discusses the role of these molecules as potential Mpro inhibitors in the prevention of SARS-CoV-2 infection.