Experimental model mimics early-stage myogenic deficit in boys with DMD | Children's National

Experimental model mimics early-stage myogenic deficit in boys with DMD | Children's National

Experimental model mimics myogenic deficit in boys with DMD An experimental model of severe Duchenne muscular dystrophy (DMD) that experiences a large spike in transforming growth factor-beta (TGFβ) activity after muscle injury shows that high TGFβ activity suppresses muscle regeneration and promotes fibroadipogenic progenitors (FAPs).