Clinical Information
Each year, at least 1.7 million adults in America develop sepsis.
Nearly 270,000 Americans die as a result of sepsis.
1 in 3 patients who dies in a hospital has sepsis.
Surveillance and Epidemiology
Tools
- Hospital Toolkit for Adult Sepsis Surveillance [PDF – 32 pages]
Centers for Disease Control and Prevention
August 2018
Presentations and Media Interviews
- A Matter of Life and Death: How States Are Tackling Sepsis as Public Policy
Association of State and Territorial Health Officials Public Health Review podcast
November 25, 2019 - Hospital Toolkit for Adult Sepsis Surveillance Webinar
Society of Critical Care Medicine Critical Care Quality Summit
September 25, 2018
Publications
- Assessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shock
JAMA Network Open
July 7, 2020 - Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012–2018*
Critical Care Medicine
March 2020 - A National Approach to Pediatric Sepsis Surveillance
Pediatrics
December 2019 - Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data
Critical Care Medicine
May 24, 2019 - Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons
Critical Care Medicine
April 2019 - Using Objective Clinical Data to Track Progress on Preventing and Treating Sepsis — CDC’s New ‘Adult Sepsis Event’ Surveillance Strategy
BMJ Quality & Safety
April 2019 - Assessing Variability in Hospital-Level Mortality Among U.S. Medicare Beneficiaries With Hospitalizations for Severe Sepsis and Septic Shock
Critical Care Medicine
November 2018 - Combined Biomarkers Predict Acute Mortality Among Critically Ill Patients With Suspected Sepsis
Critical Care Medicine
July 2018 - Variability in Determining Sepsis Time Zero and Bundle Compliance Rates for the Centers for Medicare and Medicaid Services SEP-1 Measure
Infection Control & Hospital Epidemiology
June 22, 2018 - Risk of Subsequent Sepsis Within 90 Days After a Hospital Stay by Type of Antibiotic Exposure.
Clinical Infectious Diseases
March 10, 2018 - Enhancing Recovery from Sepsis: A Review
JAMA
January 2, 2018 - Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014
JAMA
October 3, 2017 - Varying Estimates of Sepsis Mortality Using Death Certificates and Administrative Codes — United States, 1999–2014
Morbidity and Mortality Weekly Report
April 8, 2016
Prevention
Education
- Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis [Video – 1:04]
Centers for Disease Control and Prevention
June 8, 2017 - Your Guide to Infection Control and Prevention: A Webinar Series: Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis [PDF – 78 KB]
Centers for Disease Control and Prevention
May 17, 2017 - Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part I
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 2
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 3
Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 4
Quality Improvement Organizations
October 20, 2016–February 9, 2017
- Empowering Nurses for Early Sepsis Recognition [Video-1:01:40]
Centers for Disease Control and Prevention
October 25, 2016 - Advances in Sepsis: Protecting Patients Throughout the Lifespan [Video-58:47]
Centers for Disease Control and Prevention
October 25, 2016 - Think Sepsis and Act Fast [Video-4:17]
Medscape CDC Expert Commentary
September 26, 2016 - Making Health Care Safer. Think Sepsis. Time Matters. [PDF – 4 pages]
Centers for Disease Control and Prevention Vital Signs
August 2016 - Education: Webcasts, Presentations, Podcasts, Videos
Society of Critical Care Medicine Surviving Sepsis Campaign
Publications
- Combatting Sepsis: A Public Health Perspective
Clinical Infectious Diseases
May 29, 2018 - Vital Signs: Epidemiology of Sepsis: Prevalence of Health Care Factors and Opportunities for Prevention
Morbidity and Mortality Weekly Report
August 26, 2016
Treatment
Tools
- Sepsis Early Recognition and Treatment
American College of Emergency Physicians
Publications
- Toward a More Nuanced Approach to the Early Administration of Intravenous Fluids in Patients With Sepsis.
JAMA Network Open
December 7, 2018 - Current Sepsis Mandates Are Overly Prescriptive, and Some Aspects May Be Harmful.
Critical Care Medicine
December 4, 2018
Clinical Guidelines
Children
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children
Pediatric Critical Care Medicine
February 2020 - Recommendations: Special Considerations in Pediatrics [PDF – 3 pages]
Surviving Sepsis Campaign
2013 - Sepsis Quality & Patient Safety Program
Children’s Hospital Association
Adults
- Surviving Sepsis Campaign Guidelines
Society of Critical Care Medicine Surviving Sepsis Campaign
2016
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