Clinical Information | Sepsis | CDC

Clinical Information | Sepsis | CDC

Clinical Information

On This Page

• Surveillance and Epidemiology
• Prevention
• Treatment
• Clinical Guidelines

Each year, at least 1.7 million adults in America develop sepsis.

Nearly 270,000 Americans die as a result of sepsis.

1 in 3 patients who dies in a hospital has sepsis.

Surveillance and Epidemiology

Tools

• Hospital Toolkit for Adult Sepsis Surveillancepdf icon [PDF – 32 pages]
  Centers for Disease Control and Prevention
  August 2018

Presentations and Media Interviews

• A Matter of Life and Death: How States Are Tackling Sepsis as Public Policyexternal icon
  Association of State and Territorial Health Officials Public Health Review podcast
  November 25, 2019
• Hospital Toolkit for Adult Sepsis Surveillance Webinar
  Society of Critical Care Medicine Critical Care Quality Summit
  September 25, 2018

Publications

• Assessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shockexternal icon
  JAMA Network Open
  July 7, 2020
• Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012–2018*external icon
  Critical Care Medicine
  March 2020
• A National Approach to Pediatric Sepsis Surveillanceexternal icon
  Pediatrics
  December 2019
• Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Dataexternal icon
  Critical Care Medicine
  May 24, 2019
• Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisonsexternal icon
  Critical Care Medicine
  April 2019
• Using Objective Clinical Data to Track Progress on Preventing and Treating Sepsis — CDC’s New ‘Adult Sepsis Event’ Surveillance Strategy external icon
  BMJ Quality & Safety
  April 2019
• Assessing Variability in Hospital-Level Mortality Among U.S. Medicare Beneficiaries With Hospitalizations for Severe Sepsis and Septic Shockexternal icon
  Critical Care Medicine
  November 2018
• Combined Biomarkers Predict Acute Mortality Among Critically Ill Patients With Suspected Sepsisexternal icon
  Critical Care Medicine
  July 2018
• Variability in Determining Sepsis Time Zero and Bundle Compliance Rates for the Centers for Medicare and Medicaid Services SEP-1 Measureexternal icon
  Infection Control & Hospital Epidemiology
  June 22, 2018
• Risk of Subsequent Sepsis Within 90 Days After a Hospital Stay by Type of Antibiotic Exposure.external icon
  Clinical Infectious Diseases
  March 10, 2018
• Enhancing Recovery from Sepsis: A Reviewexternal icon
  JAMA
  January 2, 2018
• Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014 external icon
  JAMA
  October 3, 2017
• Varying Estimates of Sepsis Mortality Using Death Certificates and Administrative Codes — United States, 1999–2014external icon
  Morbidity and Mortality Weekly Report
  April 8, 2016

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Prevention

Education

• Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis [Video – 1:04]
  Centers for Disease Control and Prevention
  June 8, 2017
• Your Guide to Infection Control and Prevention: A Webinar Series: Sepsis Standard Work: Improving Compliance with Early Recognition and Management of Perinatal Sepsis pdf icon[PDF – 78 KB]
  Centers for Disease Control and Prevention
  May 17, 2017
• Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part Imedia iconexternal icon
  Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 2media iconexternal icon
  Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 3media iconexternal icon
  Harnessing the Home Care System for Early Sepsis Recognition & Intervention – Part 4 media iconexternal icon
  Quality Improvement Organizations
  October 20, 2016–February 9, 2017

• Empowering Nurses for Early Sepsis Recognition [Video-1:01:40]
  Centers for Disease Control and Prevention
  October 25, 2016
• Advances in Sepsis: Protecting Patients Throughout the Lifespan [Video-58:47]
  Centers for Disease Control and Prevention
  October 25, 2016
• Think Sepsis and Act Fast [Video-4:17]external icon
  Medscape CDC Expert Commentary
  September 26, 2016
• Making Health Care Safer. Think Sepsis. Time Matters. pdf icon[PDF – 4 pages]
  Centers for Disease Control and Prevention Vital Signs
  August 2016
• Education: Webcasts, Presentations, Podcasts, Videosexternal icon
  Society of Critical Care Medicine Surviving Sepsis Campaign

Publications

• Combatting Sepsis: A Public Health Perspective external icon
  Clinical Infectious Diseases
  May 29, 2018
• Vital Signs: Epidemiology of Sepsis: Prevalence of Health Care Factors and Opportunities for Prevention
  Morbidity and Mortality Weekly Report
  August 26, 2016

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Treatment

Tools

• Sepsis Early Recognition and Treatmentexternal icon
  American College of Emergency Physicians

Publications

• Toward a More Nuanced Approach to the Early Administration of Intravenous Fluids in Patients With Sepsis.external icon
  JAMA Network Open
  December 7, 2018
• Current Sepsis Mandates Are Overly Prescriptive, and Some Aspects May Be Harmful.external icon
  Critical Care Medicine
  December 4, 2018

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Clinical Guidelines

Children

• Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Childrenexternal icon
  Pediatric Critical Care Medicine
  February 2020
• Recommendations: Special Considerations in Pediatricspdf iconexternal icon [PDF – 3 pages]
  Surviving Sepsis Campaign
  2013
• Sepsis Quality & Patient Safety Programexternal icon
  Children’s Hospital Association

Adults

• Surviving Sepsis Campaign Guidelinesexternal icon
  Society of Critical Care Medicine Surviving Sepsis Campaign
  2016