Publication Date: Sep 3, 2020
Advanced Molecular Detection Clips Content
NEWS
- U.S. Will Revive Global Virus-Hunting Effort Ended Last Year
McNeil DG Jr, Kaplan T. New York Times, Aug 30, 2020. - NIH establishes Centers for Research in Emerging Infectious Diseases
(news release) NIH, Aug 27, 2020. - Scientists are reporting several cases of Covid-19 reinfection -- but the implications are complicated
Joseph A. STAT, Aug 28, 2020. - Your Coronavirus Test Is Positive. Maybe It Shouldn't Be.
Mandavilli A. New York Times, Aug 29, 2020. - XPrize Competition Hopes to Encourage 'Frequent, Fast, Cheap, and Easy' COVID-19 Testing
Ketchum K. GenomeWeb, Aug 28, 2020. - Chinese Researchers Develop CRISPR-Based Isothermal COVID-19 Diagnostic
Rizk C. GenomeWeb, Aug 27, 2020. - Covid-19 Is Threatening the In-Person Semester. Can Wastewater Testing Help Save It?
Gluckman N. Chronicle Higher Ed, Sep 1, 2020. - The mosquito strategy that could eliminate dengue
Callaway E. Nature, Aug 27, 2020.
EVENTS / TRAINING / WEB RESOURCES
- Communicable Diseases Genomics Network (CDGN)
(website) Australian Government Public Health Laboratory Network. - NIH Genetic Testing Registry (GTR) now accepting microbe tests including SARS-CoV-2 / COVID-19 tests
(announcement) NCBI Insights, Sep 1, 2020. - Ten simple rules to increase computational skills among biologists with Code Clubs.
Hagan Ada K et al. PLoS computational biology 2020 08 (8) e1008119
CONCEPTS / COMMENTS
- Emerging Pandemic Diseases: How We Got to COVID-19.
Morens David M et al. Cell 2020 Aug - Human plague: An old scourge that needs new answers.
Vallès Xavier et al. PLoS neglected tropical diseases 2020 Aug (8) e0008251 - African swine fever whole-genome sequencing-Quantity wanted but quality needed.
Forth Jan H et al. PLoS pathogens 2020 Aug (8) e1008779 - Ethical challenges in pathogen sequencing: a systematic scoping review.
Johnson Stephanie et al. Wellcome open research 2020 119
METHODS / TOOLS
- Perceived utility and feasibility of pathogen genomics for public health practice: a survey among public health professionals working in the field of infectious diseases, Belgium, 2019.
Van Goethem N et al. BMC public health 2020 Aug (1) 1318 - HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads.
Nurk Sergey et al. Genome research 2020 Aug - Coronavirus discovery by metagenomic sequencing: a tool for pandemic preparedness.
Carbo Ellen C et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2020 Aug 104594
EVOLUTION / ECOLOGY / POPULATIONS
- Ancient Bacterial Genomes Reveal a High Diversity of Treponema pallidum Strains in Early Modern Europe.
Majander Kerttu et al. Current biology : CB 2020 Aug - Mapping genome variation of SARS-CoV-2 worldwide highlights the impact of COVID-19 super-spreaders
Gomez-Carballa A, et al. Genome Res, Sep 2, 2020. - Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis.
Rueca Martina et al. Microorganisms 2020 Aug (9) - A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants
Dearlove B, et al. Proc Natl Acad Sci, Aug 31, 2020. - Comprehensive evolution and molecular characteristics of a large number of SARS-CoV-2 genomes reveal its epidemic trends.
Bai Yunmeng et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2020 Aug - Genomic surveillance revealed prevalence of unique SARS-CoV-2 variants bearing mutation in the RdRp gene among Nevada patients.
Hartley Paul et al. medRxiv : the preprint server for health sciences 2020 Aug - Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1.
Benedetti Francesca et al. Journal of translational medicine 2020 08 (1) 329 - Increased diversity and novel subtypes among clinical Cryptosporidium parvum and Cryptosporidium hominis isolates in Southern Ireland.
O' Leary Jennifer K et al. Experimental parasitology 2020 Aug 107967 - Epidemiological insights from a large-scale investigation of intestinal helminths in Medieval Europe.
Flammer Patrik G et al. PLoS neglected tropical diseases 2020 Aug (8) e0008600 - First record of a tandem-repeat region within the mitochondrial genome of Clonorchis sinensis using a long-read sequencing approach.
Kinkar Liina et al. PLoS neglected tropical diseases 2020 Aug (8) e0008552 - Pathogens, endosymbionts, and blood-meal sources of host-seeking ticks in the fast-changing Maasai Mara wildlife ecosystem.
Oundo Joseph Wang'ang'a et al. PloS one 2020 (8) e0228366 - Improved reference genome of the arboviral vector Aedes albopictus.
Palatini Umberto et al. Genome biology 2020 Aug (1) 215
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
- Precore and basal core promoter hepatitis B virus (HBV) variants are present from a young age and differ across HBV genotypes.
Lau Daryl T Y et al. Hepatology (Baltimore, Md.) 2020 Aug - Emergence of a Novel Pathogenic Recombinant Virus from Bartha Vaccine and Variant Pseudorabies Virus in China.
Bo Zongyi et al. Transboundary and emerging diseases 2020 Aug - A Model for the Production of Regulatory Grade Viral Hemorrhagic Fever Exposure Stocks: From Field Surveillance to Advanced Characterization of SFTSV.
Perez-Sautu Unai et al. Viruses 2020 Aug (9)
DETECTION / DIAGNOSIS
- Comparative Evaluation of Band-Based Genotyping Methods for Mycobacterium intracellulare and Its Application for Epidemiological Analysis.
Shin Jeong-Ih et al. Microorganisms 2020 Aug (9) - Targeted metagenomics for clinical detection and discovery of bacterial tickborne pathogens
Kingry L, et al. J Clin Microbiol, Sep 2, 2020. - Efficient high-throughput SARS-CoV-2 testing to detect asymptomatic carriers
Shental N, et al. Sci Adv, Aug 21, 2020. - Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19.
Hou Tieying et al. PLoS pathogens 2020 08 (8) e1008705 - Highly sensitive and specific diagnosis of coronavirus disease 19 (COVID-19) by reverse transcription multiple cross displacement amplification-labelled nanoparticles biosensor.
Li Shijun et al. The European respiratory journal 2020 Aug - A novel Betacoronavirus characterised in collared peccaries from the Rio de Janeiro Zoo (Brazil) killed by unknown disease.
D'arc Mirela et al. Memorias do Instituto Oswaldo Cruz 2020 e200153 - COVID-19 patients in earlier stages exhaled millions of SARS-CoV-2 per hour.
Ma Jianxin et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Aug - Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
(systematic review) Dinnes J, et al. Cochrane Library, Aug 26, 2020. - Rapid isothermal amplification and portable detection system for SARS-CoV-2
Ganguli A, et al. Proc Natl Acad Sci, Aug 31, 2020. - Porcine reproductive and respiratory syndrome virus whole-genome sequencing efficacy with field clinical samples using a poly(A)-tail viral genome purification method.
Gagnon Carl A et al. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2020 Aug 1040638720952411 - HPV-EM: an accurate HPV detection and genotyping EM algorithm.
Inkman Matthew J et al. Scientific reports 2020 Aug (1) 14340 - Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time.
Barnes Kayla G et al. Nature communications 2020 08 (1) 4131 - Evaluation of Microsatellite Typing, ITS Sequencing, AFLP Fingerprinting, MALDI-TOF MS, and Fourier-Transform Infrared Spectroscopy Analysis of Candida auris .
Vatanshenassan Mansoureh et al. Journal of fungi (Basel, Switzerland) 2020 Aug (3)
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
- Household Transmission of Carbapenemase-Producing Enterobacterales (CPE) in Ontario, Canada.
Jamal Alainna J et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Sep - How new molecular tools can help bugbusters: a Burkholderia cepacia complex outbreak investigation.
Maciel Amanda Luiz Pires et al. Revista do Instituto de Medicina Tropical de Sao Paulo 2020 e59 - Prolonged Persistence of PCR-detectable Virus During an Outbreak of SARS-CoV-2 in an Inpatient Geriatric Psychiatry Unit in King County, Washington.
Corcorran Maria A et al. American journal of infection control 2020 Aug - Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.
Lemieux Jacob et al. medRxiv : the preprint server for health sciences 2020 Aug - An Outbreak Associated with Sapovirus GI.3 in an Elementary School in Gyeonggi-do, Korea.
Cho Seung Rye et al. Journal of Korean medical science 2020 Aug (34) e281 - Phylogenetic clustering networks among heterosexual migrants with new HIV diagnoses post-migration in Australia.
Sacks-Davis Rachel et al. PloS one 2020 (9) e0237469 - Nosocomial hepatitis A outbreak among healthcare workers and patients in a community hospital during an ongoing statewide outbreak
Brennan J, et al. Infect Control Hosp Epidemiol 2020 Sep 3;1-3. - Human Immunodeficiency Virus (HIV) Outbreak Investigation Among Persons Who Inject Drugs in Massachusetts Enhanced by HIV Sequence Data.
Tumpney Matthew et al. The Journal of infectious diseases 2020 Sep (Supplement_5) S259-S267 - HIV-1 phylodynamic analysis among people who inject drugs in Pakistan correlates with trends in illicit opioid trade.
Cholette François et al. PloS one 2020 (8) e0237560
ANTIMICROBIALS / VACCINES / INTERVENTIONS
- Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine.
Keech Cheryl et al. The New England journal of medicine 2020 Sep
HOST-MICROBE INTERACTIONS
- The later stages of viral infection: An undiscovered country of host dependency factors.
King Cason R et al. PLoS pathogens 2020 Aug (8) e1008777 - Primary and Acquired Immunodeficiencies Associated with Severe Varicella-Zoster Infections.
Ansari Rahila et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Aug - Association of Body Mass Index with Fecal Microbial Diversity and Metabolites in the Northern Finland Birth Cohort.
Loftfield Erikka et al. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020 Aug - Sex differences in immune responses that underlie COVID-19 disease outcomes.
Takahashi Takehiro et al. Nature 2020 Aug - On Statistical Power for Case-Control Host Genomic Studies of COVID-19
Lin YC, et al. medRxiv, Sep 1, 2020. - COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells.
Latini Andrea et al. Genes 2020 08 (9) - Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection.
Wei Jin et al. bioRxiv : the preprint server for biology 2020 Jun
Note: indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.
Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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