HYDROXYCHLOROQUINE STUMBLES UNDER LACK OF EVIDENCE
Debate rages over whether a decades-old antimalarial, hydroxychloroquine, offers genuine promise as a potential COVID-19 treatment. The World Health Organization has included the drug in its global trial, SOLIDARITY, but its efficacy is as yet unproven.
- Pharmaceutical researcher Derek Lowe explores evidence from small trials and preprints that hydroxychloroquine is not effective against COVID-19. (Science Translational Medicine blog | 6 min read)
- Microbiologist Didier Raoult’s controversial research is the wellspring of some of the enthusiasm for the drug. The study has now received a statement of concern from the society that publishes the journal in which it appeared. (Retraction Watch | 3 min read)
- Attorney Olga Lucia Torres, who takes hydroxychloroquine to treat her lupus, describes her worries for people who rely on the drug. There have been some shortages as people snap up supplies in the wake of unsubstantiated recommendations from US President Donald Trump, prominent US media figures and Brazilian President Jair Bolsonaro. (The New York Times | 5 min read)
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