CIENCIASMEDICASNEWS: SARS-CoV-2 Detection Assay

miércoles, 15 de abril de 2020

SARS-CoV-2 Detection Assay

	Infectious Diseases
	The latest infectious diseases news from News Medical

Johns Hopkins researchers warn of new infectious diseases and death due to global warming

SARS-CoV-2 Detection Assay

To support the development of diagnostic kits, vaccines and neutralizing antibodies against SARS-CoV-2, Sino Biological Inc. has developed a panel of research reagents, including recombinant antigens (N protein, S protein, S1 and S2 subunits of S protein, and RBD domain of S protein), antibodies, antigen detection kits and genes.

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SARS-CoV-2 Proteins and Inhibitor Screening Kit

50+ SARS-CoV-2 related proteins including S, S1, S2, ACE2, N proteins and high-throughput inhibitor screening kit available at ACROBiosystem to help your research. Bioactivity validated by ELISA/SPR/BLI and protocols are offered for free.

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Treatments of COVID-19: Old Drugs, New Tricks

COVID-19 is a global pandemic caused by the SARS-CoV-2 virus. There is a huge worldwide effort underway to discover vaccines and new drugs, and to repurpose old drugs to treat this disease.

This talk will discuss the drugs that are currently being used to treat COVID-19: remdesivir, chloroquine and the combination of lopinavir/ritonavir. These drugs are being investigated as part of the World Health Organisation’s ‘Solidarity’ international clinical trial. Remdesivir is an anti-viral drug with no other clinical use at present; lopinavir/ritonavir are used for treating HIV. Chloroquine and its related analogue hydroxychloroquine are anti-malarials discovered during one of the major global emergencies of the 20th century – World War II. After a brief introduction to the SARS-CoV-2 virus and the viral life cycle, the structures and mechanisms of action of these drugs will be described.

	Loss of smell and taste as symptoms of COVID-19 Professor Carl Philpott speaks to News-Medical about his research into smell loss as a potential early symptom for COVID-19.

	What we know about COVID-19 in children A new viewpoint article published in the journal JAMA Pediatrics in April 2020 discusses the manifestation and management of the novel coronavirus disease devastating several countries.

	Lessons from Italy's COVID-19 pandemic underscore the need for more research A new viewpoint article published in the journal JAMA Internal Medicine dissects different factors that contributed to the dire COVID-19 situation in Italy, emphasizing several aspects relevant to the international healthcare community.

	New anti-COVID-19 system could potentially fight other viruses The ongoing COVID-19 pandemic has sparked many research projects to meet the challenge of the virus and come up with measures to fight its activity. A new study published in the journal Cell Host & Microbe in April 2020 describes a novel system to help scientists understand the virus, including mutations, diagnose infections, and also to develop and evaluate vaccines more quickly.

	Trial assesses tissue plasminogen activator as a treatment for COVID-19-related respiratory failure A new study published online in the Journal of Trauma and Acute Care Surgery in March 2020 reports that the anticoagulation drug tPA could be a potential aid in managing respiratory failure in patients with COVID-19.