CIENCIASMEDICASNEWS: NMR Characterisation of Polysaccharide-Based Vaccines

miércoles, 22 de abril de 2020

NMR Characterisation of Polysaccharide-Based Vaccines

	Infectious Diseases
	The latest infectious diseases news from News Medical

NMR Characterisation of Polysaccharide-Based Vaccines

Polysaccharide-protein conjugate vaccines are among the safest and most successful vaccines developed during the last 30 years.

Since the first semisynthetic chemical conjugate vaccine licensed in the 1980’s to protect human against Haemophilus influenzae type b infection, conjugate vaccines against Neisseria meningitidis and Streptococcus pneumoniae have been developed and registered using the same approach (i.e. bacterial growth to produce capsular polysaccharide antigen and chemical coupling to carrier protein).

In this seminar a description of the use of proton NMR for structural identity and conformity testing of carbohydrate-based vaccines is provided.

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