First test of in-body gene editing shows promise- Preliminary results suggest that treatment for rare disease is safe, but its effectiveness is unclear

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Last Posted: Sep 06, 2018

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• First test of in-body gene editing shows promise- Preliminary results suggest that treatment for rare disease is safe, but its effectiveness is unclear
  H Ledford, Nature, September 5, 2018
• CRISPR is too fat for many therapies, so scientists are putting the genome editor on a diet
  J Cohen, Science, August 30, 2018
• Cas9 immunity creates challenges for CRISPR gene editing therapies
  JM Crudele et al, Nature Comm, August 29, 2018
• Ethical Issues Regarding CRISPR Mediated Genome Editing.
  Shinwari Zabta Khan et al. Current issues in molecular biology 2018 26103-110
• New Study Explains Why Genetic Mutations Cause Disease in Some People but Not in Others
  Columbia Systems Biology News, August 2018
• Newest form of CRISPR corrects genetic disease in viable human embryos, with few errors
  S Begley, Stat News, August 20, 2018
• p53 activation: a checkpoint for precision genome editing?
  Conti Anastasia et al. Genome medicine 2018 Aug 10(1) 66
• Science and Bioethics of CRISPR-Cas9 Gene Editing: An Analysis Towards Separating Facts and Fiction.
  Cribbs Adam P et al. The Yale journal of biology and medicine 2017 90(4) 625-634
• Did CRISPR really fix a genetic mutation in these human embryos?
  E Callaway, Nature, August 8, 2018
• Keep calm and edit on
  Nature Biotechnology, August 6, 2018

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