Novel Influenza A(H7N2) Virus in Chickens, Jilin Province, China, 2014 - Volume 20, Number 10—October 2014 - Emerging Infectious Disease journal - CDC
Volume 20, Number 10—October 2014
Novel Influenza A(H7N2) Virus in Chickens, Jilin Province, China, 2014
Influenza subtype H7 viruses have been detected in poultry worldwide; associated human disease ranges from mild to severe (1–8). Human infections with influenza A(H7N9) viruses were first identified in China in March 2013 (9). As of March 11, 2014, a total of 375 laboratory-confirmed cases of human infection with influenza A(H7N9) virus, including 115 deaths, had been reported to the World Health Organization (10).
On February 21, 2014, the National Health and Family Planning Commission of China notified the World Health Organization of a laboratory-confirmed case of human infection with influenza virus subtype H7N9 (11). The patient was a 50-year-old farmer who lived in Jilin Province and traded chickens for a living. He became ill on February 15 and was confirmed to be infected with H7N9 virus on February 21. He recovered 2 weeks later. Although H7N9 viruses had been detected in live poultry markets in 12 provinces in China (12,13), the virus had not been detected in Jilin Province, in poultry or humans. To locate the origin of the infection, we conducted influenza virus surveillance among poultry in the patient’s village.
Dr Shi is a veterinary epidemiologist at the Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China. His research focuses on the surveillance, diagnostic, and molecular epidemiology of avian influenza viruses.
This study was supported by the Ministry of Science and Technology (KJYJ-2013-01-01,KJYJ-2013-01-01-02, and 2012ZX10004214), and by the China Agriculture Research System (CARS-42-G08), and by Ningxia Science and Technology Department (2013ZZN30).
- Capua I, Mutinelli F, Pozza MD, Donatelli I, Puzelli S, Cancellotti FM. The 1999–2000 avian influenza (H7N1) epidemic in Italy: veterinary and human health implications. Acta Trop. 2002;83:7–11 .
- Du Ry van Beest Holle M, Meijer A, Koopmans M, de Jager CM. Human-to-human transmission of avian influenza A/H7N7, The Netherlands, 2003. Euro surveillance: 2005 10:264–8. PMID: 16371696
- Koopmans M, Wilbrink B, Conyn M, Natrop G, van der Nat H, Vennema H, Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands. Lancet. 2004;363:587–93.
- Nguyen-Van-Tam JS, Nair P, Acheson P, Baker A, Barker M, Bracebridge S, Outbreak of low pathogenicity H7N3 avian influenza in UK, including associated case of human conjunctivitis. Euro surveillance: 2006;11:E060504 2. PMID:16816456
- Skowronski DM, Tweed SA, Petric M, Booth T, Li Y, Tam T. Human illness and isolation of low-pathogenicity avian influenza virus of the H7N3 subtype in British Columbia, Canada. J Infect Dis. 2006;193:899–900.
- Tweed SA, Skowronski DM, David ST, Larder A, Petric M, Lees W, Human illness from avian influenza H7N3, British Columbia. Emerg Infect Dis.2004;10:2196–9.
- Abbott A. Human fatality adds fresh impetus to fight against bird flu. Nature. 2003;423:5.
- Belser JA, Blixt O, Chen LM, Pappas C, Maines TR, Van Hoeven N, Contemporary North American influenza H7 viruses possess human receptor specificity: implications for virus transmissibility. Proc Natl Acad Sci U S A. 2008;105:7558–63.
- World Health Organization. Human infection with influenza A(H7N9) virus in China; 31 March 2013 [cited 2014 May 18].http://www.who.int/csr/don/2013_04_01/en/
- World Health Organization. WHO risk assessment of human infection with avian influenza A(H7N9) virus; 11 April 2014 [cited 2014 May 18].http://www.who.int/influenza/human_animal_interface/influenza_h7n9/140225_H7N9RA_for_web_20140306FM.pdf?ua=1.pdf
- World Health Organization. Human infection with avian influenza A(H7N9) virus––update; 21 February 2014 [cited 2014 May 18].http://www.who.int/csr/don/2014_02_24/en/
- Shi J, Deng G, Liu P, Zhou J, Guan L, Li W, Isolation and characterization of H7N9 viruses from live poultry markets—implication of the source of current H7N9 infection in humans. Chin Sci Bull. 2013;58:1857–63.
- Zhang Q, Shi J, Deng G, Guo J, Zeng X, He X, H7N9 influenza viruses are transmissible in ferrets by respiratory droplet. Science. 2013;341:410–4.
- World Health Organization. WHO manual on animal influenza diagnosis and surveillance.2002 [cited 2014 May 18].http://www.who.int/csr/resources/publications/influenza/en/whocdscsrncs20025rev.pdf
- Zhang H, Li X, Guo J, Li L, Chang C, Li Y, The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus. J Gen Virol. 2014;95:779–86.
Suggested citation for this article: Shi J, Deng G, Zeng X, Kong H, Wang X, Lu K, et al. Novel influenza A(H7N2) virus in chickens, Jilin Province, China, 2014. Emerg Infect Dis [Internet]. 2014 Oct [date cited]. http://dx.doi.org/10.3201/eid2010.140869