Evidence Reviews & Guidelines in Genomic Medicine
CDC-NIH workshop paper: Evidence synthesis & guideline development in genomic medicine: Current status & future prospects.
Guidelines we can trust, report from the Institute of Medicine
CDC blog post: Guidelines we can trust are crucial for the successful implementation of genomic medicine
The CDC EGAPP initiative- Lessons learned over a decade
Genomics Translation
Evaluation of Genomic Applications in Practice and Prevention (EGAPP™)
Fact Sheet: Identifying Opportunities to Improve Health and Transform Healthcare [PDF 139.91 KB]
In 2004, the Centers for Disease Control and Prevention launched the EGAPP initiative to establish and test a systematic, evidence-based process for evaluating genetic tests and other applications of genomic technology that are in transition from research to clinical and public health practice.
A key EGAPP goal is to provide objective, timely, and credible information that is clearly linked to available scientific evidence. This information will allow health care providers and payers, consumers, policymakers, and others to distinguish genetic tests that are safe and useful.
How EGAPP Works
- EGAPP Steering CommitteeThe EGAPP Steering Committee is a federal, interagency group that oversees the recruitment and selection of the independent EGAPP Working Group members.
- EGAPP Working Group
The EGAPP Working Group is an independent group that develops recommendations andevidence-based reviews on genetic tests. To be considered for membership on the EGAPP Working Group please complete the nomination process.
CDC Resources
- CDC Summaries of EGAPP Recommendation Statements
- CDC-sponsored EGAPP evidence reports
- EGAPP initiative poster [PDF 233KB]
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