Tuberculosis & Genomics: What's the Connection?

http://www.cdc.gov/genomics/update/current.htm

Tuberculosis & Genomics: What's the Connection?

CDC information: World TB day Find TB. Treat TB. Working together to eliminate TB.

Treatment practices, outcomes, and costs of multidrug-resistant and extensively drug-resistant tuberculosis, United States, 2005–2007. 
Emerging Infectious Diseases, May 2014

Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients
Matthias Merker, et al. PLOS One (December, 2013)

Whole-genome sequencing and social-network analysis of a tuberculosis outbreak
Jennifer L. Gardy et al. NEJM (2011)

Whole genome sequencing versus traditional genotyping for investigation of a Mycobacterium tuberculosis outbreak: A longitudinal molecular epidemiological study.  
Andreas Roetzer et al. PLOS Medicine (2013)

Did you know? More than 660 publications have reported on more than 300 genes in relation to tuberculosis susceptibility & outcomes, including 10 genomewide association studies. To find out more, visit the HuGE Navigator