Tuberculosis, Drug Resistance & Genomics

Genomics|Update|Current

Tuberculosis, Drug Resistance & Genomics

CDC information on tuberculosis
Genomes reveal roots of TB drug resistance. Tuberculosis strains evolve by gradually acquiring subtle mutations.
Ed Yong Nature News, Sep 1
Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis.
Maha R Farhat, et al.  Nat Genetics 2013 Sep 1
Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.
Hongtai Zhang, et al. Nat Genetics, August 2013
Decoding drug-resistant TB- Researchers characterize drug-resistant tuberculosis by analyzing the genomes of more than 500 Mycobacterium tuberculosis isolates from around the world, by Tracy Vence, The Scientist, Sep 1
TB  has  human,  not animal, origins,  Julie Gould, BBC News, Sep 2
Did you know? 291 genes have been reported with risk of Tuberculosis and outcomes, including   9 genomewide association studies. To find out more, visit the HuGE Navigator