sábado, 20 de julio de 2013



Free online issue Volume 32, No 29
18 July 2013

ISSN: 0950-9232
EISSN: 1476-5594
2011 impact factor 6.373*
18/194 Oncology
16/157 Genetics & Heredity
34/180 Cell Biology
37/289 Biochemistry & Molecular Biology
Douglas R. Green
*2011 Journal Citation Reports (Thomson Reuters, 2012)


The future of next generation sequencing?
A web focus from European Journal of Human Genetics and Oncogene
Next generation sequencing is rapidly pervading all areas of Human genetics: improving speed, precision, and last but not least breadth of diagnostics; opening up new avenues of screening; are screening and testing still different or is there a confluence? In parallel, it profoundly affects basic biology discovery by unravelling mutation mechanisms and causes and consequences in gene regulation and what goes wrong in genetic disease and cancer. Besides many insights, the data deluge also brings questions: on how to handle this, internally and towards the patients; the role of geneticists in the process; how - and if - to integrate direct to consumer services; how to maintain a proper public-private balance to allow therapy development but avoid undue restrictions in data access.
Follow the contributions to this debate in European Journal of Human Genetics and Oncogene.
'Open' option for authors
Oncogene offers authors the option to publish their articles with immediate open access upon publication. Open access articles will also be deposited on PubMed Central at the time of publication and will be freely available immediately. Find out more from our FAQs page.
Using animals properly
Read the updated guidelines on the welfare and use of animals in cancer research. All experiments should incorporate the 3Rs: replacement, reduction and refinement. Recommendations in this BJC article include topics in study design, choice of tumor models, and humane endpoints.

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