July 2013, Vol. 10, No. 5, Pages 463-471 , DOI 10.2217/pme.13.35
(doi:10.2217/pme.13.35)
Perspective
Epigenetics and personalized medicine: prospects and ethical issues
As scientific knowledge about gene–environment interactions and the role of epigenetic factors in gene expression grows, new possibilities for personalized medicine may be opened up. In particular, the associations that have been demonstrated between epigenetic markers and certain diseases are an exciting development for personalized medicine. These advances also create new ethical challenges, regarding causal and moral responsibility, due to unique characteristics of how epigenetic effects regulate gene expression, are established and may change over the course of a person’s life. This article examines the ethical implications of integrating epigenetic knowledge into personalized medicine.
Users who read this article also read:
Personalized medicine: challenges and opportunities for translational bioinformatics Casey Lynnette Overby, Peter Tarczy-HornochSummary | Full Text | PDF (635 KB) | PDF Plus(636 KB) | Add to Favorites | Related | Reprints & Permissions |
 News & Views in ... Personalized Medicine CUSTOM demonstrates feasibility and challenges of genetics-guided clinical trials Light shed on genetic causes of epileptic encephalopathies New genetic insights into pathway heterogeneity in schizophrenia Metabolomics could provide a way to diagnose Alzheimer’s disease using blood tests |
Challenges for implementing next-generation sequencing-based genome diagnostics: it’s also the people, not just the machines Joris A Veltman, Edwin Cuppen, Terry VrijenhoekSummary | Full Text | PDF (603 KB) | PDF Plus(661 KB) | Add to Favorites | Related | Reprints & Permissions |
Clinical trials for precision oncology using next-generation sequencing Richard Simon, Eric PolleySummary | Full Text | PDF (639 KB) | PDF Plus(656 KB) | Add to Favorites | Related | Reprints & Permissions |
.png)
No hay comentarios:
Publicar un comentario