Diagnostic chest x-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers.

Source

Epidemiology, Cancer Prevention Institute of California.

Abstract

Background: The effects of low-dose medical radiation on breast cancer risk are uncertain, and few studies have included genetically susceptible women, such as those who carry germline BRCA1 and BRCA2 mutations. Methods: We studied 454 BRCA1 and 273 BRCA2 mutation carriers aged <50 0.64-2.11="" 1.16="" 1.22="" 3-5="" 50="" 6="" a="" adjusting="" after="" age="" analysis.="" and="" are="" associated="" association="" australia="" before="" between="" brca1="" brca2="" breast="" but="" by="" canada="" cancer="" carriers.="" carriers="" cases="" chest="" ci="0.62-2.42)" comparing="" conclusions:="" confidence="" considered="" controls="" diagnostic="" do="" doses="" elevated="" estimated="" estimates="" ew="" excluding="" exposure="" factors="" family="" few="" findings="" fluoroscopy="" for="" from="" further="" genetically="" given="" higher="" history="" imaging="" impact:="" in="" increasing="" interval="" involving="" ionizing="" known="" mammograms="" more="" mutation="" mutations="" not="" odds="" of="" or="" our="" p="" pneumonia="" positive="" predisposed="" radiation="" ratio="" registries="" reported="" results:="" risk="" self-reported.="" significant="" statistically="" studies="" support="" the="" those="" three="" to="" tuberculosis="" usa="" use="" warranted.="" was="" we="" were="" with="" without="" women="" x-rays.="" x-rays="" years="" zealand.="">