Improving the Efficiency and Effectiveness of Genomic Science Translation: A Workshop
- December 3, 2012 (8:30 AM Pacific)
- Beckman Center (Huntington Room) • 100 Academy Drive, Irvine, CA 92617 Map
- Biomedical and Health Research, Public Health
- Roundtable on Translating Genomic-Based Research for Health
- Board on Health Sciences Policy
Historically, the process for translating basic science into clinical application has been expressed as a linear progression from discovery to clinical application development to careful regulatory testing to approval and, finally, to wide-spread use by the medical community. Recently, there has been some concern that the productivity of this pathway has decreased. There has not been, for instance, an increase in the number of approved drugs despite significant increases in our understanding of human health and disease biology. In fact, most of the anticipated health care development that was predicted at the completion of the Human Genome Project has not, for the most part, culminated in products or processes that are used in medical settings. This lack of translation between basic genome science and clinical research has frustrated many scientists, health care practitioners, investors, policy makers, and patients.
A number of inefficiencies and areas in need of improvement have been identified in the translation process. These include misaligned academic incentives, a relative lack of funding of translational research grants, and animal models that do not accurately translate for human biology or disease. Additionally, knowledge from outcomes and end clinical or public health needs are not routinely incorporated into the design of basic scientific research and the process of handing off discoveries between basic and clinical scientists is not well defined.
Improving the translation of genomic discoveries will require collaborative efforts among stakeholders to encourage innovative and transformational research. The Roundtable on Translating Genomic-Based Research for Health will host a workshop to examine how basic science can best be positioned to foster successful translation of early genomic discoveries. The presentations and discussions will explore the challenges in and identify potential opportunities for improving the efficacy of the translation process. Stakeholders including academic researchers, industry representatives, policy makers, and ot hers will be invited to present their perspectives.
This meeting will take place at the Beckman Center in Irvine, California.
Upcoming Meetings for this Activity
- Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests: A Workshop February 27, 2013 (8:30 AM Eastern) Register
Previous Meetings for this Activity
- Assessing the Economics of Genomic Medicine: A Workshop July 17, 2012 - July 18, 2012 (8:30 AM Eastern)
- Evidence for Clinical Utility of Molecular Diagnostics in Oncology: A Workshop May 24, 2012 (8:30 AM Eastern)