Clinical Pharmacology & Therapeutics - Multimodal Dynamic Profiling of Healthy and Diseased States for Future Personalized Health Care

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Clinical Pharmacology & Therapeutics - Multimodal Dynamic Profiling of Healthy and Diseased States for Future Personalized Health Care

Development

Clinical Pharmacology & Therapeutics (2013); 93 1, 29–32. doi:10.1038/clpt.2012.204

Multimodal Dynamic Profiling of Healthy and Diseased States for Future Personalized Health Care

G I Mias¹ and M Snyder¹

¹Department of Genetics, Stanford University School of Medicine, Stanford, California, USA

Correspondence: M Snyder, (mpsnyder@stanford.edu)

Received 15 August 2012; Accepted 6 October 2012
Accepted article preview online 12 October 2012; Advance online publication 28 November 2012

Personalized medicine is rapidly emerging as the future direction in the post–genome sequencing era. Early applications have concentrated on variant-based assessment of individual disease risks. Technological advances and dropping costs now allow for expanding the domain of personalized medicine to include multimodal and dynamic monitoring of individuals (including transcriptomic, proteomic, and metabolomic longitudinal profiling). Such efforts may lead to effective diagnostic and precise monitoring tools that can be applied in a clinical setting.