Seroprevalence of Influenza A(H1N1)pdm09 Virus Antibody, England, 2010 and 2011 - - Emerging Infectious Disease journal - CDC

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Seroprevalence of Influenza A(H1N1)pdm09 Virus Antibody, England, 2010 and 2011 - - Emerging Infectious Disease journal - CDC




Table of Contents
Volume 18, Number 11–November 2012

Dispatch

Seroprevalence of Influenza A(H1N1)pdm09 Virus Antibody, England, 2010 and 2011

Article Contents

• The Study
• Conclusions
• Acknowledgments
• References
• Figure 1
• Figure 2
• Table 1
• Table 2
• Technical Appendix  [155 KB - 3 pages]
• Suggested Citation

Katja Hoschler , Catherine Thompson, Nick Andrews, Monica Galiano, Richard Pebody, Joanna Ellis, Elaine Stanford, Marc Baguelin, Elizabeth Miller, and Maria Zambon

Author affiliations: Health Protection Agency, London, UK (K. Hoschler, C. Thompson, N. Andrews, M. Galiano, R. Pebody; J. Ellis, M. Baguelin, E Miller, M. Zambon); and Health Protection Agency, Manchester, UK (E. Stanford)

Suggested citation for this article

Abstract

The intense influenza activity in England during the 2010–11 winter resulted from a combination of factors. Population-based seroepidemiology confirms that the third wave of influenza A(H1N1)pdm09 virus circulation was associated with a shift in age groups affected, with the highest rate of infection in young adults.

Seroepidemiologic data collected in England during the first 2 influenza pandemic waves suggested that another wave of infection with influenza A(H1N1)pdm09 virus was unlikely during 2010–11 (1). However, a substantial third wave occurred that affected persons in older age groups (2). Severity indicators suggested a higher level of illness and death, with increased cases in critical care and deaths. We conducted further seroepidemiologic study in England during 2010–11 to identify possible reasons for these observations.