CDC has released a report and updated recommendations that detail how states and healthcare facilities should deal with carbapenem-resistant Enterobacteriaceae (CRE), deadly germs that cause healthcare-associated infections. CRE are resistant to almost all drugs and can contribute to death in 40% of patients who become infected. In response to this emerging threat, CDC has urged state health departments to find out how common CRE are in acute care facilities in their states and to follow several key steps to protect patients.
Many states are actively working to prevent CRE from spreading within their healthcare facilities, for example:
Wisconsin implemented statewide surveillance of CRE to find out how common these infections are, identify where and how they spread, and guide control efforts to prevent CRE from becoming widespread in healthcare settings. They were the first state to mandate public reporting of CRE to CDC’s National Healthcare Safety Network (NHSN). Currently, 137 Wisconsin hospitals are searching for CRE and have detected CRE in seven hospitalized patients.
http://www.cdc.gov/hai/state-based/pdfs/HAIpreventionStories_WI_CRE_508.pdf
CDC - NHSN
Minnesota developed recommendations to guide their healthcare facilities in CRE prevention. To date, no outbreaks or transmission of CRE have been detected among Minnesota facilities that have conducted active surveillance testing.
http://www.cdc.gov/hai/state-based/pdfs/HAIpreventionStories_MN_CRE_508.pdf
To learn more about these and other state healthcare-associated infection prevention stories, please visit http://www.cdc.gov/hai/state-based/success_stories.html.
See what your state is doing to prevent healthcare-associated infections: http://www.cdc.gov/HAI/state-based/index.html.
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CDC - 2012 CRE Toolkit - HAI
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CDC - Carbapenem-resistant Enterobacteriaceae - HAI
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Carbapenem-Resistant Enterobacteriaceae Containing New Delhi Metallo-Beta-Lactamase in Two Patients — Rhode Island, March 2012
2012 CRE Toolkit - Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE)
Carbapenem-resistant Enterobacteriaceae (CRE) are a serious threat to public health. Infections with CRE are difficult to treat and have been associated with mortality rates as high as 40-50%(1). Due to the movement of patients throughout the healthcare system, if CRE are a problem in one facility, then typically they are a problem in other facilities in the region as well. To help protect patients and prevent transmission, CDC has released a CRE toolkit which expands on the 2009 CDC recommendations and continues to be updated as new information becomes available.Table of Contents
- Introduction
- Background
- Definitions
- Part 1: Facility-level CRE Prevention
- Part 2: Regional CRE Prevention: Recommended
Strategies for Health Department Implementation
- Public Health Engagement
- Regional Surveillance for CRE
- Regional Prevention Strategies
- Appendix A: Previous and Current Clinical and Laboratory Standards Institute Interpretive Criteria for Carbapenems and Enterobacteriaceae
- Appendix B: General Approach to Carbapenem-resistant Enterobacteriaceae(CRE) Control in Facilities that Rarely or Have Not Identified CRE
- Appendix C: Example of a Survey for Infection Preventionists
- Survey of Healthcare Facilities for Carbapenem-resistant Enterobacteriaceae (CRE)
- Selected References
- Refers to: Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008;29:1099-106.
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