Education May Protect Brain From Exposure to Solvents

More schooling seems to preserve thinking skills as chemical workers age, study says

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_125666.html
(*this news item will not be available after 08/27/2012)

By Mary Elizabeth Dallas

Tuesday, May 29, 2012

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TUESDAY, May 29 (HealthDay News) -- People with less than a high school education who work with solvents may have problems with their thinking skills later in life, according to a study of people in France.

In the study, researchers from Harvard University noted that people with more education did not experience the same types of issues with their thinking, or so-called "cognitive," skills, even if they had the same amount of exposure to these chemicals.

"People with more education may have a greater cognitive reserve that acts like a buffer, allowing the brain to maintain its ability to function in spite of damage," study author Lisa Berkman, of Harvard University in Cambridge, Mass., said in news release from the American Academy of Neurology. "This may be because education helps build up a dense network of connections among brain cells."

In conducting the study, the investigators followed more than 4,100 people who worked at the French national gas and electric company. While working at the company, the participants were exposed to four types of solvents: chlorinated solvents, petroleum solvents, benzene and non-benzene aromatic solvents.

The researchers assessed the workers' lifetime exposure to these solvents and tested their thinking skills when they were an average of 59 years old. By this time, 91 percent of the study participants were retired.

Most of those studied worked at the company for their entire career and 58 percent had less than a high school education. Of those without a high school diploma, the study revealed 32 percent had problems with their thinking skills. In contrast, only 16 percent of those with more education had similar thinking problems, the findings showed.

The study, published in the May 29 issue of Neurology, also found that high levels of exposure to chlorinated and petroleum solvents was associated with 14 percent greater risk for thinking problems among the less-educated workers, compared to their peers with no exposure.

Moreover, the less-educated workers with a high level of exposure to benzene were 24 percent more likely to have problems with their thinking skills, and those with significant exposure to non-benzene aromatic solvents were 36 percent more likely to have such problems.

"These findings suggest that efforts to improve quality and quantity of education early in life could help protect people's cognitive abilities later in life," Berkman said. "Investment in education could serve as a broad shield against both known and unknown exposures across the lifetime. This is especially important given that some evidence shows that federal levels of permissible exposure for some solvents may be insufficient to protect workers against the health consequences of exposure."

While the study uncovered an association between education level, solvent exposure and thinking skills, it did not prove a cause-and-effect relationship.

SOURCE: American Academy of Neurology, news release, May 28, 2012

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