Genogroup I and II Picobirnaviruses in Respiratory Tracts of Pigs - Vol. 17 No. 12 - December 2011 - Emerging Infectious Disease journal - CDC
Volume 17, Number 12—December 2011
Genogroup I and II Picobirnaviruses in Respiratory Tracts of Pigs
A thorough understanding of virus diversity in animals provides epidemiologic baseline information about potential pathogens and can lead to identification of emerging human pathogens. On the basis of relevance to reemerging viruses, such as Nipah virus and influenza A virus, pigs are a key risk host for emerging RNA virus–associated disease in humans in different areas (1–3). In an effort to identify unknown porcine viruses in the respiratory tracts of pigs, we performed sequence-independent amplification on partially purified viral nucleic acid from swab samples of respiratory tracts from pigs that were PCR negative for influenza A virus (4–6).
AbstractSequence-independent amplification and specific reverse transcription PCRs identified genogroup I and II picobirnaviruses in respiratory tracts of pigs. These data expand knowledge of picobirnavirus diversity and tropism. Genetic relationships between porcine respiratory and human enteric picobirnaviruses suggest cross-species transmission of picobirnaviruses between pigs and humans.
Suggested citation for this article: Smits SL, Poon LLM, van Leeuwen M, Lau P-N, Perera HKK, Malik Peiris JS, et al. Genogroup I and II picobirnaviruses in respiratory tracts of pigs. Emerg Infect Dis [serial on the Internet]. 2011 Dec [date cited]. http://dx.doi.org/10.3201/eid1712.110934