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Melioidosis, Phnom Penh, Cambodia
Erika Vlieghe, Comments to Author Lim Kruy, Birgit De Smet, Chun Kham, Chhun Heng Veng, Thong Phe, Olivier Koole, Sopheak Thai, Lut Lynen, and Jan Jacobs
Author affiliations: Institute of Tropical Medicine, Antwerp, Belgium (E. Vlieghe, B. DeSmet, O. Koole, L. Lynen, J. Jacobs); and Sihanouk Hospital Centre of Hope Phnom Penh, Cambodia (L. Kruy, C. Kham, C.H. Veng, T. Phe, S. Thai)
Suggested citation for this article
Abstract
We describe 58 adult patients with melioidosis in Cambodia (2007–2010). Diabetes was the main risk factor (59%); 67% of infections occurred during the rainy season. Bloodstream infection was present in 67% of patients, which represents 12% of all bloodstream infections. The case-fatality rate was 52% and associated with inappropriate empiric treatment.
Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is endemic to Southeast Asia and tropical Australia (1,2). B. pseudomallei is a gram-negative bacterium that causes lung or soft tissue infections with or without bloodstream infection (BSI) (3); the case-fatality rate can exceed 80%. Treatment includes third-generation cephalosporins or carbapenems, followed by maintenance courses of sulfamethoxazole/trimethoprim (SMX/TMP) with or without doxycycline.
In Cambodia, few microbiologically confirmed cases have been described (4–7). We describe 58 adult patients in whom melioidosis was diagnosed during July 1, 2007–January 31, 2010, at Sihanouk Hospital Centre of Hope, Phnom Penh, Cambodia.
full-text:
Melioidosis, Phnom Penh, Cambodia | CDC EID: "EID Journal Home > Volume 17, Number 7–July 2011 - Enviado mediante la barra Google"
Suggested Citation for this Article
Vlieghe E, Kruy L, De Smet B, Kham C, Veng CH, Phe T, et al. Melioidosis, Phnom Penh, Cambodia. Emerg Infect Dis [serial on the Internet]. 2011 Jul [date cited]. http://www.cdc.gov/EID/content/17/7/1289.htm
DOI: 10.3201/eid1707.101069
Comments to the Authors
Please use the form below to submit correspondence to the authors or contact them at the following address:
Erika Vlieghe, Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium; email: evlieghe@itg.be
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