viernes, 20 de enero de 2012

Bias in the Reporting of Family History: Impli... [J Genet Couns. 2012] - PubMed - NCBI

J Genet Couns. 2012 Jan 12. [Epub ahead of print]

Bias in the Reporting of Family History: Implications for Clinical Care.

Source

Institute for Health Policy Studies, Department of Surgery, University of California, San Francisco, CA, USA, elissa.ozanne@ucsfmedctr.org .

Abstract

Family history of cancer is critical for identifying and managing patients at risk for cancer. However, the quality of family history data is dependent on the accuracy of patient self reporting. Therefore, the validity of family history reporting is crucial to the quality of clinical care. A retrospective review of family history data collected at a community hospital between 2005 and 2009 was performed in 43,257 women presenting for screening mammography. Reported numbers of breast, colon, prostate, lung, and ovarian cancer were compared in maternal relatives vs. paternal relatives and in first vs. second degree relatives. Significant reporting differences were found between maternal and paternal family history of cancer, in addition to degree of relative. The number of paternal family histories of cancer was significantly lower than that of maternal family histories of cancer. Similarly, the percentage of grandparents' family histories of cancer was significantly lower than the percentage of parents' family histories of cancer. This trend was found in all cancers except prostate cancer. Self-reported family history in the community setting is often influenced by both bloodline of the cancer history and the degree of relative affected. This is evident by the underreporting of paternal family histories of cancer, and also, though to a lesser extent, by degree. These discrepancies in reporting family history of cancer imply we need to take more care in collecting accurate family histories and also in the clinical management of individuals in relation to hereditary risk.

PMID:
22237666
[PubMed - as supplied by publisher]
Bias in the Reporting of Family History: Impli... [J Genet Couns. 2012] - PubMed - NCBI

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