Coffee’s link to Parkinson’s risk may depend on how your body handles caffeine

https://www.news-medical.net/news/20260902/Coffeee28099s-link-to-Parkinsone28099s-risk-may-depend-on-how-your-body-handles-caffeine.aspx Why does coffee appear to have different links with Parkinson’s risk from one person to another? A study of more than 435,000 people points to the interplay between caffeine metabolism, genetics, and sex. In a recent study published in the journal npj Parkinson's disease, researchers investigated whether the cytochrome P450 1A2 (CYP1A2) genotype and sex modify the association between Parkinson's disease (PD) and coffee consumption.