GIPR signaling opens brain’s gate for GLP-1 weight-loss therapy

A new study uncovers how GIPR signaling in brain cells helps GLP-1 weight-loss drugs bypass the blood-brain barrier and amplify their appetite-suppressing effects, offering a mechanistic explanation for the clinical power of co-agonists. https://www.news-medical.net/news/20250814/GIPR-signaling-opens-braine28099s-gate-for-GLP-1-weight-loss-therapy.aspx