Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer ++++++

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancerA new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms." https://www.news-medical.net/news/20250710/Understanding-resistance-to-EGFR-targeted-therapies-in-head-and-neck-cancers-and-breast-cancer.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_11_july_2025 Watch: She’s at high risk of breast cancer. She moved, and her screening costs soared. https://www.news-medical.net/news/20250710/Watch-Shee28099s-at-high-risk-of-breast-cancer-She-moved-and-her-screening-costs-soared.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_11_july_2025 Watch: She’s at high risk of breast cancer. She moved, and her screening costs soared.Kelli Reardon undergoes an MRI twice a year to screen for breast cancer, a measure she said she must take to protect her health. Her mother died of the disease at age 48, putting Reardon at higher risk, and Reardon has dense breast tissue, which makes it harder to detect a growth through a mammogram. Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity https://www.news-medical.net/news/20250707/Metabolic-enzyme-PHGDH-found-to-play-a-surprising-role-in-breast-cancer-immunity.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_11_july_2025 Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunityMacrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor progression and dampening immune responses. Energy waves on cancer cell surfaces linked to tumor growth and aggressiveness https://www.news-medical.net/news/20250709/Energy-waves-on-cancer-cell-surfaces-linked-to-tumor-growth-and-aggressiveness.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_11_july_2025 In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of power-generating waves on the covering, or membrane, of these cells. KAIST scientists develop tool to fight drug resistance in cancer https://www.news-medical.net/news/20250708/KAIST-scientists-develop-tool-to-fight-drug-resistance-in-cancer.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_11_july_2025 KAIST scientists develop tool to fight drug resistance in cancerOne of the biggest obstacles in cancer treatment is drug resistance in cancer cells. Conventional efforts have focused on identifying new drug targets to eliminate these resistant cells, but such approaches can often lead to even stronger resistance. Preeclampsia in pregnancy reduces risk of some cancers but raises endometrial cancer odds https://www.news-medical.net/news/20250707/Preeclampsia-in-pregnancy-reduces-risk-of-some-cancers-but-raises-endometrial-cancer-odds.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_11_july_2025 Preeclampsia in pregnancy reduces risk of some cancers but raises endometrial cancer oddsWomen with preeclampsia in their first pregnancy had a lower risk of developing breast, cervical, and lung cancer later in life, but a higher risk of endometrial cancer. The large Nordic cohort study also found that siblings of women with PE had a modestly reduced risk of cancer, particularly lung cancer.