Comparative Effectiveness of Medical Therapies for Locally Advanced Gastric Adenocarcinoma

Comparative Effectiveness of Medical Therapies for Locally Advanced Gastric Adenocarcinoma: This systematic review’s (SR) primary goal was to summarize pertinent evidence on the medical treatment for non-metastatic, locally advanced gastric adenocarcinoma to inform interest holders. This review will be used to inform a Clinical Practice Guideline by the American Society of Clinical Oncology (ASCO) on this topic. Specifically, the SR will 1) determine comparative effectiveness and harms of medical therapies and 2) determine how treatment effectiveness and harms vary by tumor-specific variables and subpopulations.