viernes, 31 de mayo de 2024
COVID-19 associated with higher risk of erectile dysfunction
https://www.news-medical.net/news/20240531/COVID-19-associated-with-higher-risk-of-erectile-dysfunction.aspx
Existing drug shows promise as treatment for rare genetic disorder NIH researchers find new pathways towards treatment for autoimmune polyendocrine syndrome type 1.
https://www.nih.gov/news-events/news-releases/existing-drug-shows-promise-treatment-rare-genetic-disorder
A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers identified the treatment based on their discovery that the syndrome is linked to elevated levels of interferon-gamma (IFN-gamma), a protein involved in immune system responses, providing new insights into the role of IFN-gamma in autoimmunity. The study, led by researchers at NIAID, was published today in the New England Journal of Medicine.
https://www.niaid.nih.gov/news-events/existing-drug-shows-promise-treatment-rare-genetic-disorder?utm_campaign=+60793797&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=
Novel Vaccine Concept Generates Immune Responses that Could Produce Multiple Types of HIV Broadly Neutralizing Antibodies
https://www.niaid.nih.gov/news-events/novel-vaccine-concept-generates-immune-responses-could-produce-multiple-types-hiv?utm_campaign=+60782895&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=
Using a combination of cutting-edge immunology & technologies, an HIV vaccine concept generated immune responses that could produce multiple types of HIV broadly neutralizing antibodies (bNAbs) in a NIAID-supported animal study. The results will inform the development of an HIV vaccine regimen for humans. The findings were published in Nature Immunology.
Collaborative Communities: Addressing Health Care Challenges Together
https://www.fda.gov/about-fda/cdrh-strategic-priorities-and-updates/collaborative-communities-addressing-health-care-challenges-together?utm_medium=email&utm_source=govdelivery
Recently, the U.S. Food and Drug Administration’s (FDA) Center for Devices and Radiological Health (CDRH) began participating in three new collaborative communities in the medical device ecosystem:
Implantable Brain-Computer Interface Collaborative Community (iBCI-CC): Aims to facilitate advances and innovation in iBCIs, to empower each user of an iBCI to lead a fuller and more independent life.
OpenOximetry Collaborative Community: Seeks to improve the safety and accuracy of pulse oximeters in all populations.
Smart and Autonomous Medical Systems (SaAMS) Collaborative Community: Seeks to advance the maturity, adoption, and clinical use of SaAMS to improve patient care.
Most Detailed 3D Reconstruction of Human Brain Tissue Ever Produced Yields Surprising Insights Posted on May 30th, 2024 by Dr. Monica M. Bertagnolli
https://directorsblog.nih.gov/2024/05/30/most-detailed-3d-reconstruction-of-human-brain-tissue-ever-produced-yields-surprising-insights/
The NIH Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative has expanded scientists’ understanding of the human brain in recent years, offering fascinating insights into the ways that individual cells and complex neural circuits interact dynamically to enable us to think, feel, and act. But neuroscientists still have much more to learn about how our brains are put together at the most fundamental, subcellular level.
As a step in that direction, in a new study supported in part by the NIH BRAIN Initiative and reported in the journal Science, researchers have created the most detailed nanoscale resolution map ever produced of a cubic millimeter of brain tissue, about the size of half a grain of rice.
Mast cells control lung type 2 inflammation via prostaglandin E2-driven soluble ST2
https://www.cell.com/immunity/abstract/S1074-7613(24)00254-1?utm_term=&utm_campaign=60800870&utm_medium=email&utm_content=&utm_source=govdelivery
Allergy news: NIAID-funded researchers identified a novel mechanism by which immune cells known as mast cells may protect from allergic inflammation, such as that seen in asthma and allergic disease. They found that mast cells use a unique pathway to reduce allergy-related inflammation in mice, and showed that this mechanism is likely similar in human allergic disease. This finding is surprising because mast cells are primarily believed to cause allergic reactions rather than protect from them. This function of mast cells could inform new approaches to treating allergy and asthma in people. The findings were published in Immunity.
FDA grants accelerated approval to selpercatinib for pediatric patients two years and older with RET-altered metastatic thyroid cancer or solid tumors
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-selpercatinib-pediatric-patients-two-years-and-older-ret-altered?utm_medium=email&utm_source=govdelivery
On May 29, 2024, the Food and Drug Administration granted accelerated approval to selpercatinib (Retevmo, Eli Lilly and Company) for pediatric patients two years of age and older with the following:
advanced or metastatic medullary thyroid cancer (MTC) with a RET mutation, as detected by an FDA-approved test, who require systemic therapy;
advanced or metastatic thyroid cancer with a RET gene fusion, as detected by an FDA-approved test, who require systemic therapy and who are radioactive iodine-refractory (if radioactive iodine is appropriate); and
locally advanced or metastatic solid tumors with a RET gene fusion, as detected by an FDA-approved test, that have progressed on or following prior systemic treatment or who have no satisfactory alternative treatment options.
An Emergency Department Screening Strategy Identifies Asymptomatic and Undiagnosed Syphilis
https://www.niaid.nih.gov/news-events/emergency-department-screening-strategy-identifies?utm_campaign=+60777242&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=
As syphilis rates continue to rise in the United States, emergency departments may be a way for people with limited healthcare access to get screening and treatment. A NIAID study derived an emergency department syphilis screening strategy to help people get diagnosed before their infection reaches an advanced stage.
jueves, 30 de mayo de 2024
13 Israeli med-tech startups that could transform healthcare Some of the 150 companies that presented at the BioMed 2024 international conference, showcasing advances in genetic medicine, neurology, and more.
13 Israeli med-tech startups that could transform healthcare
Some of the 150 companies that presented at the BioMed 2024 international conference, showcasing advances in genetic medicine, neurology, and more.
https://www.israel21c.org/13-israeli-med-tech-startups-that-could-transform-healthcare/
Short bursts of teaching can help people with autism learn skills Researchers suggest that by utilizing so-called “memory flashes,” people with autism are able to pick up and apply new skills faster.
Short bursts of teaching can help people with autism learn skills
Researchers suggest that by utilizing so-called “memory flashes,” people with autism are able to pick up and apply new skills faster.
https://www.israel21c.org/short-bursts-of-teaching-can-help-people-with-autism-learn-skills/
How to easily start an outdoor exercise routine Finding an exercise buddy makes it a lot harder to cancel exercise plans at the last minute Associated Press Published May 29, 2024 2:08pm EDT
How to easily start an outdoor exercise routine
Finding an exercise buddy makes it a lot harder to cancel exercise plans at the last minute
Associated Press
Published May 29, 2024 2:08pm EDT
https://www.foxnews.com/health/how-easily-start-outdoor-exercise-routine
Early stroke symptoms, plus allergy prevention and foods that promote sleep And more of the top Fox News Health stories and videos from the past week By Fox News Staff Fox News Published May 29, 2024 4:38pm EDT
Early stroke symptoms, plus allergy prevention and foods that promote sleep
And more of the top Fox News Health stories and videos from the past week
By Fox News Staff Fox News
Published May 29, 2024 4:38pm EDT
https://www.foxnews.com/health/early-stroke-symptoms-allergy-prevention-foods-promote-sleep
For a better night's sleep, try eating more of these foods, researchers say Eating more fruits and veggies could help support better sleep, study suggests Angelica Stabile By Angelica Stabile Fox News Published May 28, 2024 5:13pm EDTFor a better night's sleep, try eating more of these foods, researchers say Eating more fruits and veggies could help support better sleep, study suggests Angelica Stabile By Angelica Stabile Fox News Published May 28, 2024 5:13pm EDT
For a better night's sleep, try eating more of these foods, researchers say
Eating more fruits and veggies could help support better sleep, study suggests
Angelica Stabile By Angelica Stabile Fox News
Published May 28, 2024 5:13pm EDT
https://www.foxnews.com/health/better-nights-sleep-try-eating-foods-researchers-say
Ask a doctor: ‘Why am I hearing my heartbeat in my ears?’ Two medical experts revealed the causes of that strange ‘whooshing’ sound By Erica Lamberg Fox News Published May 29, 2024 5:15pm EDT
Ask a doctor: ‘Why am I hearing my heartbeat in my ears?’
Two medical experts revealed the causes of that strange ‘whooshing’ sound
By Erica Lamberg Fox News
Published May 29, 2024 5:15pm EDT
https://www.foxnews.com/health/ask-doctor-why-hearing-heartbeat-ears
Michigan mom: ‘I had a stroke at 39 — and the warning signs weren’t what you’d expect’ A wife and mother reveals her near-death experience to raise awareness of young women’s risk Melissa Rudy By Melissa Rudy Fox News Published May 29, 2024 5:30am EDT
Michigan mom: ‘I had a stroke at 39 — and the warning signs weren’t what you’d expect’
A wife and mother reveals her near-death experience to raise awareness of young women’s risk
Melissa Rudy By Melissa Rudy Fox News
Published May 29, 2024 5:30am EDT
https://www.foxnews.com/health/michigan-mom-stroke-39-warning-signs-werent-what-youd-expect
Feeding peanuts to babies could prevent allergies through the teen years, study finds Peanut allergies were up to 71% less likely among children who ate peanuts in first 5 years of life Melissa Rudy By Melissa Rudy Fox News Published May 28, 2024 7:35pm EDT
Feeding peanuts to babies could prevent allergies through the teen years, study finds
Peanut allergies were up to 71% less likely among children who ate peanuts in first 5 years of life
Melissa Rudy By Melissa Rudy Fox News
Published May 28, 2024 7:35pm EDT
https://www.foxnews.com/health/feeding-peanuts-babies-could-prevent-allergies-teen-years-study-finds
First person with MS to play in the NBA shares his inspiring message: 'Make the most of it' Chris Wright has learned to view his diagnosis of multiple sclerosis as a ‘badge of honor’ Melissa Rudy By Melissa Rudy Fox News Published May 30, 2024 5:00am EDT
First person with MS to play in the NBA shares his inspiring message: 'Make the most of it'
Chris Wright has learned to view his diagnosis of multiple sclerosis as a ‘badge of honor’
Melissa Rudy By Melissa Rudy Fox News
Published May 30, 2024 5:00am EDT
https://www.foxnews.com/health/first-person-ms-play-nba-shares-inspiring-message-make-most
miércoles, 29 de mayo de 2024
Role of FoxP3+ Regulatory T Cells in Modulating Immune Responses to Adeno-Associated Virus Gene Therapy
https://www.liebertpub.com/doi/10.1089/hum.2023.227?utm_campaign=HUM%20FP%20May%2029%2C%202024%20AD&utm_content=Article2&utm_term=&utm_medium=email&utm_source=Adestra
Abstract
Adeno-associated virus (AAV) gene therapy is making rapid strides owing to its wide range of therapeutic applications. However, development of serious immune responses to the capsid antigen or the therapeutic transgene product hinders its full clinical impact. Immune suppressive (IS) drug treatments have been used in various clinical trials to prevent the deleterious effects of cytotoxic T cells to the viral vector or transgene, although there is no consensus on the best treatment regimen, dosage, or schedule. Regulatory T cells (Tregs) are crucial for maintaining tolerance against self or nonself antigens. Of importance, Tregs also play an important role in dampening immune responses to AAV gene therapy, including tolerance induction to the transgene product. Approaches to harness the tolerogenic effect of Tregs include the use of selective IS drugs that expand existing Tregs, and skew activated conventional T cells into antigen-specific peripherally induced Tregs. In addition, Tregs can be expanded ex vivo and delivered as cellular therapy. Furthermore, receptor engineering can be used to increase the potency and specificity of Tregs allowing for suppression at lower doses and reducing the risk of disrupting protective immunity. Because immune-mediated toxicities to AAV vectors are a concern in the clinic, strategies that can enhance or preserve Treg function should be considered to improve both the safety and efficacy of AAV gene therapy.
Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus
https://www.liebertpub.com/doi/10.1089/hum.2024.034?utm_campaign=HUM+FP+May+29%2C+2024+AD&utm_content=Article1&utm_term=&utm_medium=email&utm_source=Adestra
Abstract
The development of bone-targeting drug delivery systems holds immense promise for improving the treatment of skeletal diseases. By precisely delivering therapeutic agents to the affected areas of bone, these strategies can enhance drug efficacy, minimize off-target effects, and promote patient adherence, ultimately leading to improved treatment outcomes and an enhanced quality of life for patients. This review aims to provide an overview of the current state of affinity-based bone-targeting agents and recent breakthroughs in innovative bone-targeting adeno-associated virus (AAV) strategies to treat skeletal diseases in mice. In particular, this review will delve into advanced AAV engineering, including AAV serotype selection for bone targeting and capsid modifications for bone-specific tropism. Additionally, we will highlight recent advancements in AAV-mediated gene therapy for skeletal diseases and discuss challenges and future directions of this promising therapeutic approach.
Antimicrobial resistance: an enormous, growing, and unevenly distributed threat to global health
https://www.thelancet.com/infographics-do/antibiotic-resistance-series-2024?dgcid=hubspot_email_conferencealerts_lancetamr24&utm_campaign=conferencealerts&utm_medium=email&_hsenc=p2ANqtz-_E-RzBcsQ791U3ZSxbZPbvSzCVhlFK7DhW0LjaeW_aRJ8CrsH4OIyKGrCGgH5ZHy4n74oGYbQneFvPy4MsoFO21UOBAA&_hsmi=309014326&utm_content=309014326&utm_source=hs_email
Each year, an estimated 7·7 million deaths are associated with bacterial infections, 1·27 million of which are caused by bacterial pathogens resistant to the antibiotics available to treat them.
Treatments for blindness target the retina and the brain | Drug Discovery News
Treatments for blindness target the retina and the brain | Drug Discovery News: Researchers are developing gene and cell therapies and prosthetics to help patients with blindness regain some vision. The first major prosthetic, the Argus II, was just discontinued. Where will the field go from here?
Treatments for blindness target the retina and the brain | Drug Discovery News
Treatments for blindness target the retina and the brain | Drug Discovery News: Researchers are developing gene and cell therapies and prosthetics to help patients with blindness regain some vision. The first major prosthetic, the Argus II, was just discontinued. Where will the field go from here?
Safer eye floater treatments come with a burst of nanobubbles | Drug Discovery News
Safer eye floater treatments come with a burst of nanobubbles | Drug Discovery News: Between invasive surgery or risky laser therapy, people suffering from severe eye floaters have no great treatment options. Now, with the development of a safer and less invasive nanoparticle-based therapy, people with floaters may finally get their vision and quality of life back.
Rejuvenating the retina to save vision | Drug Discovery News
Rejuvenating the retina to save vision | Drug Discovery News: In diabetic macular edema, senescent cells build up in the retina, leading to vision loss. A new drug forces these undead cells to die, healing the retina.
Heat waves associated with increased risk of preterm birth in the U.S. Annalisa Merelli By Annalisa Merelli May 28, 2024
https://www.statnews.com/2024/05/28/extreme-heat-increased-risk-preterm-delivery-stillbirth-study-says/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8Z-QV9l0U9wTdnqKRBv--_GToBzoQ3oWWM_7plrJOY3sqwTbxOjM636lK9yGG-Q4uXsvMznpS34OfdrCTPBsDZh7PgNQ&_hsmi=309132552&utm_content=309132552&utm_source=hs_email
Heat waves are linked to early deliveries, per study
Heat waves are becoming more frequent and more intense across the world, and as temperatures rise, so do health risks. It can be especially dangerous for those with cardiovascular or chronic diseases — and several studies have identified an increased risk of preterm delivery and stillbirth after heat exposure. STAT’s Nalis Merelli reported yesterday on a new study that confirms the link to early deliveries at a massive scale.
The research, published last week in JAMA Network Open, looked at more than 53 million singleton births that occurred in the 50 most populous U.S. cities during the hottest months of the year between 1993 and 2017. After a heat wave, preterm births increased by 2% and early births by 1%. But the effects were uneven: Mothers who were 29 or younger, had a lower level of education, and belonged to a minority ethnic or racial group saw a 4% increase in preterm births, and a 3% increase in early deliveries.
What we know about extreme heat’s health impacts after the hottest summer on record
Theresa Gaffney
By Theresa Gaffney May 14, 2024
https://www.statnews.com/2024/05/14/hottest-summer-2000-years-nature-study-climate-change-effects-health/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8WP2SC69rJKH40Q_mf3WRm7tpot0-L7Kmxw2mK5qMDKmrcc5m5Bz8-Mg388FIhP-EpsHqr56BoC6mDUqkUXd1ZrIV_sQ&_hsmi=309132552&utm_content=309132552&utm_source=hs_email
4 Things To Know About Depression and Older Adults
https://www.nia.nih.gov/health/mental-and-emotional-health/4-things-know-about-depression-and-older-adults?utm_source=nia-eblast&utm_medium=email&utm_campaign=healthyaging-20240529
Depression is common among older adults, but it isn’t a normal part of aging. It can affect how you feel, think, and act. While dealing with depression can be difficult, you don’t need to tackle it alone. That’s why it’s important to seek support from family, friends, and health care professionals early on.
Scientists Map Networks Regulating Gene Function in the Human Brain NIH-funded research details the brain’s cellular and molecular regulatory elements and their impact on brain functionScientists Map Networks Regulating Gene Function in the Human Brain NIH-funded research details the brain’s cellular and molecular regulatory elements and their impact on brain function
https://www.nimh.nih.gov/news/science-news/scientists-map-networks-regulating-gene-function-in-the-human-brain
Scientists Map Networks Regulating Gene Function in the Human Brain
A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain’s biological pathways and cellular functions. The research, supported the National Institutes of Health (NIH), used postmortem brain tissue from over 2,500 donors to map gene regulation networks across different stages of brain development and multiple brain-related disorders.
FDA Approves First Interchangeable Biosimilar for Two Rare Diseases
https://www.fda.gov/news-events/press-announcements/fda-approves-first-interchangeable-biosimilar-two-rare-diseases?utm_medium=email&utm_source=govdelivery
On May 28, 2024, the U.S. Food and Drug Administration approved Bkemv (eculizumab-aeeb) as the first interchangeable biosimilar to Soliris (eculizumab) to treat certain rare diseases. Bkemv is approved for the following treatment indications, which are also currently approved for Soliris:
the treatment of patients with paroxysmal nocturnal hemoglobinuria (PNH) to reduce hemolysis; and
the treatment of patients with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy.
“Many rare conditions are life-threatening, and many do not have treatments,” said Sarah Yim, director of the Office of Therapeutic Biologics and Biosimilars in the FDA’s Center for Drug Evaluation and Research. “The FDA is committed to help facilitate the development of safe and effective interchangeable biosimilar treatments that can expand access for individuals with rare diseases whose current treatment options are limited.”
A disease is considered rare if it affects fewer than 200,000 people in the U.S. The conditions PNH and aHUS are rare diseases characterized by the breakdown of red blood cells. PNH results in anemia (low red blood cells), thrombosis (blood clots), pancytopenia (low counts of red blood cells, white blood cells, and platelets) and dark urine, while aHUS results in anemia, thrombocytopenia (low platelets) and kidney failure.
martes, 28 de mayo de 2024
Introducing Peanut in Infancy Prevents Peanut Allergy into Adolescence NIH Study Finds Protection Lasts No Matter How Often Kids Eat Peanut in Later Childhood
https://www.niaid.nih.gov/news-events/introducing-peanut-infancy-prevents-peanut-allergy-adolescence?utm_campaign=+60763522&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=
Feeding children peanut products regularly from infancy to age 5 years reduced the rate of peanut allergy in adolescence by 71%, even when the children ate or avoided peanut products as desired for many years. These new findings, from a study sponsored and co-funded by NIAID, provide conclusive evidence that achieving long-term prevention of peanut allergy is possible through early allergen consumption. The results were published today in the journal NEJM Evidence.
Attention-Deficit / Hyperactivity Disorder (ADHD)
https://www.cdc.gov/adhd/articles/adhd-across-the-lifetime.html?CDC_AAref_Val=https://www.cdc.gov/ncbddd/adhd/features/adhd-across-the-lifetime.html?utm_source=news-releases-email-A&utm_medium=email&utm_campaign=may-28-2024&utm_content=intro-inline-module&j=2369319&sfmc_sub=6992026&l=69_HTML&u=55839760&mid=100038678&jb=1002
ADHD symptoms often start in childhood and continue into adulthood, but they may look different in adults. Just as ADHD symptoms and the way they impact daily living may change across the lifetime, needs for support and treatment may differ for adults and children.
The doctor would treat her sickle cell pain crisis — if she promised not to get an abortion Eric Boodman By Eric Boodman
A ‘deal with the devil’: A doctor would only treat a woman’s sickle cell pain if she didn’t have an abortion
https://www.statnews.com/2024/05/28/sickle-cell-pregnancy-risks-in-abortion-restricted-state/
In Part 2 of STAT’s yearlong investigation into the systematic denial of reproductive autonomy for people with sickle cell disease, Eric Boodman highlights a troubling incident: A woman’s pain management specialist in Texas agreed to treat her only if she agreed not to have an abortion, despite her fears that pregnancy complications could kill her. “He told me that he would give me pain medicine while I was in the hospital if I decided to keep the baby,” she told Eric. Read that story here.
Last week, Eric reported on another facet of the coercive care that has faced patients with sickle cell disease for decades: doctors pressuring them into unwanted sterilizations, framing them as potentially life-saving, without fully-informed consent about their potential irreversibility.
How doctors are pressuring sickle cell patients into unwanted sterilizations
Eric Boodman
By Eric Boodman May 21, 2024
https://www.statnews.com/2024/05/21/sickle-cell-patients-steered-toward-sterilization-for-decades/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--bAIClWIc_b9zaCUwqXW_-4G0S6XbcX9xBUg-RCY12iFWVNFE3A-vSqLeSH_hQ7N3-XuDPyS0Yqmspov9QhW4T9cYeCQ&_hsmi=308658169&utm_content=308658169&utm_source=hs_email
Fish oil supplements linked to greater first-time heart attack risk in study: ‘Not universally good or bad' Cardiologist, dietitians share cautions, tips on fish oil supplements and new study: ‘More isn’t always better’ Melissa Rudy By Melissa Rudy Fox News Published May 23, 2024 7:15pm EDT | Updated May 26, 2024 5:29pm EDT
Fish oil supplements linked to greater first-time heart attack risk in study: ‘Not universally good or bad'
Cardiologist, dietitians share cautions, tips on fish oil supplements and new study: ‘More isn’t always better’
Melissa Rudy By Melissa Rudy Fox News
Published May 23, 2024 7:15pm EDT | Updated May 26, 2024 5:29pm EDT
https://www.foxnews.com/health/fish-oil-supplements-linked-greater-first-time-heart-attack-risk-not-universally-good-bad
5 myths about schizophrenia, according to a mental health expert: ‘Huge stigma’ For World Schizophrenia Day, a psychiatric nurse practitioner shares some of the most common misconceptions Melissa Rudy By Melissa Rudy Fox News Published May 24, 2024 5:00am EDT
5 myths about schizophrenia, according to a mental health expert: ‘Huge stigma’
For World Schizophrenia Day, a psychiatric nurse practitioner shares some of the most common misconceptions
Melissa Rudy By Melissa Rudy Fox News
Published May 24, 2024 5:00am EDT
https://www.foxnews.com/health/myths-schizophrenia-according-mental-health-expert-huge-stigma
8 of the biggest health stories from this week in case you missed them Catch up here on supplement side effects, crisis skills, sleep signs and much more Melissa Rudy By Melissa Rudy Fox News Published May 26, 2024 4:00am EDT
8 of the biggest health stories from this week in case you missed them
Catch up here on supplement side effects, crisis skills, sleep signs and much more
Melissa Rudy By Melissa Rudy Fox News
Published May 26, 2024 4:00am EDT
https://www.foxnews.com/health/8-biggest-health-stories-week-case-missed-them
Nurses speak out: 'What I wish I'd known before entering the profession' 6 nurses reveal key lessons learned in a high-stress health care job — and why it matters Melissa Rudy By Melissa Rudy Fox News Published May 28, 2024 5:00am EDTNurses speak out: 'What I wish I'd known before entering the profession' 6 nurses reveal key lessons learned in a high-stress health care job — and why it matters Melissa Rudy By Melissa Rudy Fox News Published May 28, 2024 5:00am EDT
Nurses speak out: 'What I wish I'd known before entering the profession'
6 nurses reveal key lessons learned in a high-stress health care job — and why it matters
Melissa Rudy By Melissa Rudy Fox News
Published May 28, 2024 5:00am EDT
https://www.foxnews.com/health/nurses-speak-out-what-wish-known-entering-profession
lunes, 27 de mayo de 2024
From warhead to cancer-killer, the quest for more actinium-225 | Drug Discovery News
From warhead to cancer-killer, the quest for more actinium-225 | Drug Discovery News: Actinium-225 is a radioactive isotope that kills cancer cells with a burst of alpha particles, but it was difficult to make enough of it — until now.
Silencing cancer with CAR T cells | Drug Discovery News
Silencing cancer with CAR T cells | Drug Discovery News: A new approach to cell engineering could make off-the-shelf CAR T cell therapies a reality.
Beta blockers may alleviate anxiety in children with autism | Drug Discovery News
Beta blockers may alleviate anxiety in children with autism | Drug Discovery News: The benefits of propranolol, which reduces heart rate and blood pressure, might extend to anxiety associated with autism spectrum disorder.
Silencing genes to prevent disease with RNAi drugs | Drug Discovery News
Silencing genes to prevent disease with RNAi drugs | Drug Discovery News: Alnylam Pharmaceuticals develops therapeutics based on the RNA interference (RNAi) pathway discovered in 1998.
Noninvasive genetic analysis boosts embryo quality checks | Drug Discovery News
Noninvasive genetic analysis boosts embryo quality checks | Drug Discovery News: The spent media of human embryo cultures may hold clues that help doctors distinguish normal embryos from abnormal ones.
A reengineered spinal cord stimulator restores touch and reduces pain | Drug Discovery News
A reengineered spinal cord stimulator restores touch and reduces pain | Drug Discovery News: A reengineered spinal cord stimulator restores touch and reduces pain
I survived having five miscarriages. This is what all that pain taught me about hope By Nicole Zasowski Fox News Published May 26, 2024 10:00am EDT
I survived having five miscarriages. This is what all that pain taught me about hope
Maybe your story is similar to mine. Or, perhaps you’ve weathered different storms, such as chronic illness, a ruptured relationship, or the death of a dream
By Nicole Zasowski Fox News
Published May 26, 2024 10:00am EDT
https://www.foxnews.com/opinion/survived-having-five-miscarriages-what-all-that-pain-taught-about-hope
domingo, 26 de mayo de 2024
Clues From Bird Flu’s Ground Zero on Dairy Farms in the Texas Panhandle By Amy Maxmen MAY 23, 2024
https://kffhealthnews.org/news/article/bird-flu-ground-zero-texas-dairy-farms-whodunit-h5n1/?utm_campaign=KFF-This-Week&utm_medium=email&_hsenc=p2ANqtz-8GvyRouLSCMhZRlj3seDUu4ZbbGyBdCg5JMvTzmpc2GQ2gvZxjUZyqIgYBUe-NP8XykdwQjxUyxjRZF5gf7hWvcpe15Q&_hsmi=308617290&utm_content=308617290&utm_source=hs_email
Strengthening HPV Vaccination Coverage, Data Quality, and Communication in Europe with project PERCH
https://www.hpvworld.com/articles/strengthening-hpv-vaccination-coverage-data-quality-and-communication-in-europe-with-project-perch/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--DoDO2SU-EHpHiMrcRgESgDgbEanZSTic5n_gBBQMPRHrqRTBQ9nidm12kB4qJ8tOtCZ1E99WAlU7faHy0qLG6dTHU8A&_hsmi=308523819&utm_content=308523819&utm_source=hs_email#:~:text=In%20the%20WHO%20European%20Region,%25%20to%20more%20than%2090%25.
HPV vaccine study finds zero cases of cervical cancer among women vaccinated before age 14
Annalisa Merelli
By Annalisa Merelli Jan. 25, 2024
https://www.statnews.com/2024/01/25/hpv-vaccine-prevent-cervical-cancer-cervarix-gardasil-study/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--evnx9P4h7k5IPVk_PffX9LYZ1wOYsJeUMVy3zivNT0LhZ1m9qWDWTzQwL-qEblZfQ0yFwdi8QyBUJz159cdQ21OzazQ&_hsmi=308523819&utm_content=308523819&utm_source=hs_email
Human papillomavirus vaccines work — for women and men. A large dataset released yesterday ahead of the American Society of Clinical Oncology’s annual meeting showed that in a cohort of 1.7 million patients, vaccinated men had 3.4 cases of HPV-caused cancer per 100,000 patients, compared to 7.5 cases per 100,000 in unvaccinated men. For vaccinated female patients, the incidence was 11.5 per 100,000 patients, compared to 15.8 per 100,000 unvaccinated women.
Yet rates of HPV vaccination in men remain very low. Vaccination in male adolescents and young adults in the U.S. improved from 7.8% to 36.4% between 2011 and 2020. But that means a majority of men are still missing out on a lifesaving vaccine, reports my colleague Matt Herper — and so are a majority of women. Though female vaccination rates went up from 37.7% to 49.4% in the same period, they are still far below the 90% goal established by the WHO.
New data show the HPV vaccine prevents cancer in men, too. Why don’t more people get it?
Matthew Herper
By Matthew Herper May 23, 2024
https://www.statnews.com/2024/05/23/hpv-vaccine-cancer/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-85PqPBQJECt80PXFJv-Zot7-v6eG6ydAp0NCvM5X66HI7ZzqkkGDSTrHiB5lD4IZx1hxMwqaoFk6P3xW3UAKElWGq9hA&_hsmi=308523819&utm_content=308523819&utm_source=hs_email
The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics Published: May 23, 2024
https://www.thelancet.com/series/antibiotic-resistance?utm_campaign=tlpr&utm_medium=email&_hsenc=p2ANqtz-93w49O-7d0_4kKppIQyJpKSV9YL9v_Mrze-AloN-bj7ysQEWQXYd6vW4IX9MBkj-GA-ws1LVceCRh-uPGvRWOT4JjfnjMpG3_vsVAPHbGh3F-IbK4&_hsmi=307834864&utm_content=307834864&utm_source=hs_email
Access to effective antibiotics is essential to every health system in the world, however, antimicrobial resistance (AMR) threatens this backbone of modern medicine and is already leading to deaths and disease which would have once been prevented. This Series highlights that, although AMR can affect anyone throughout the life course, the very young, very old and severely ill are the ones suffering the most. Through novel modelling data, this Series shows how stopping infections through improved vaccination and water and sanitation can not only prevent a significant proportion of deaths due to AMR in low- and middle-income countries, but also reduce the use of antibiotics to preserve its effectiveness. The Series also addresses how a rethink of drug development is needed to support investment in antibiotic, diagnostics, and vaccine development according to the burden of infection and resistance. Lower drug development costs will also make antibiotics more affordable and accessible. Finally, the authors argue for the need of targets to trigger political commitment and accelerate progress in addressing AMR.
FDA advisers endorse Guardant Health’s colon cancer screening test Angus Chen Jonathan Wosen By Angus Chen and Jonathan Wosen May 23, 2024
https://www.statnews.com/2024/05/23/guardant-fda-shield-colon-cancer-blood-screening-panel-recommend/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--rcqGaItN7hqVXGG0ZW25pYCgM8mHi9eUPDWciheHSYzfYtGa3IX64EQlq6W4JClanQfXlNue-o-8a0Bf6aU2vfoOk0g&_hsmi=308523819&utm_content=308523819&utm_source=hs_email
An independent panel of advisers to the Food and Drug Administration yesterday recommended the agency approve a blood-based colon cancer detection test made by Guardant Health. In a prospective study of 20,000 participants, the test detected 100% of colon cancers at stage 2 or later.
The test is still less sensitive than a colonoscopy: It detects 65% of stage 1 cancers, and just 13% of precancerous polyps. But a blood-based test would be more convenient than a colonoscopy, which could encourage more patients to keep up with screening. Currently, a third of patients fall behind on recommended screening, which contributes to the majority of colon cancer deaths, report STAT’s Angus Chen and Jonathan Wosen.
After MDMA therapy, she considered suicide. The trial data tell a different story Olivia Goldhill By Olivia Goldhill May 24, 2024
After MDMA therapy, she considered suicide. The trial data tell a different story
Olivia Goldhill
By Olivia Goldhill May 24, 2024
https://www.statnews.com/2024/05/24/mdma-treatment-ptsd-fda-asked-to-probe-adverse-events/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9xjaYJnG14CU2pVec0LpK8d5esUn2rRqkWgbqDH5yd93wZsJ15BuH8zCyhRW7DWFN9R1IXl2dLXcMZqaq6cw-tP3X-DQ&_hsmi=308523819&utm_content=308523819&utm_source=hs_email
The psychedelic MDMA has the potential to treat post-traumatic stress disorder, and the FDA is currently reviewing results from two Phase 3 trials of the drug from the Multidisciplinary Association for Psychedelic Studies. But the promising data behind the treatment may overlook significant adverse effects: My colleague Olivia Goldhill reports the case of a Phase 2 trial participant who developed suicidal ideation and whose PTSD worsened during the study — events that don’t seem to be reported in the data.
Now the Institute for Clinical and Economic Review, a non-profit that evaluates the cost-effectiveness of drugs, is asking the FDA to look into potential data omissions. Meanwhile, a citizen petition signed by prominent psychedelic researchers is asking the FDA to hold an extended public hearing to discuss concerns. “There’s a pattern when something goes wrong, it’s anything but the MDMA or psychedelics,” said Neşe Devenot, a former MAPS volunteer and co-author of the petition. Read more about the debate.
Women in RARE
https://editions.rarerevolutionmagazine.com/html5/reader/production/default.aspx?pubname=&edid=17784672-cf4c-4bad-b1c0-41cc985a8f41&pnum=78
Every day, I mask the pain underneath my jeans. I’m at war with my body. At war with my skin. It’s torture. Absolute torment. I live with an unforgiving, relentless, heartbreaking rare disease, especially for women and children. It’s a thief. It robs women of beauty, intimacy, sexuality, womanhood and confidence—always taking, never giving. Written by Carrie Hodgin
SMA Europe: a global leader for change for people with spinal muscular atrophy
SMA Europe: a global leader for change for people with spinal muscular atrophy
https://rarerevolutionmagazine.com/digitalspotlight/sma-europe-a-global-leader-for-change-for-people-with-spinal-muscular-atrophy/
The role of chest reconstructive surgery for paediatric Poland Syndrome patients Fecha y hora31 may 2024 09:00 a. m.
https://zoom.us/webinar/register/8017153415769/WN_dt1wHAwAS6GuFSOb2__-8A#/registration
PIP-UK Poland Syndrome Support & Network trustee Peter Bannister is hosting a medical webinar on 31 May 2024 at 1:00pm BST. The webinar aims to educate and share knowledge with medical professionals on the role of chest reconstructive surgery in treating Poland syndrome, including a round table discussion with some key opinion leaders in the field. It will also end with a Q&A session, where the panel of experts will address the queries of attendees. To register for this webinar, visit https://bit.ly/3WBT0gR.
PIP-UK is working hard to improve the lives of people living with Poland Syndrome.
https://pip-uk.org/
Wellbeing Hub Resources and information to help you live as well as possible with your rare condition
https://www.rareminds.org/wellbeing-hub/
Rareminds has launched its new Wellbeing Hub, featuring resources and information to help people with rare conditions live well. The Wellbeing Hub can help provide information about diagnosis, relationships, navigating healthcare and more. Find out more about Rareminds' Wellbeing at rareminds.org/wellbeing-hub
How CLN2 Batten disease changed our life: “A Mother’s Love”
https://rarerevolutionmagazine.com/how-cln2-batten-disease-changed-our-life-a-mothers-love/
My name is Gail Rich and our two daughters were both diagnosed with CLN2 Batten disease in late 2016. We also have a son, Louis, who is 13 years old.
How to file a complaint about a hospital emergency department
https://www.cms.gov/priorities/your-patient-rights/emergency-room-rights/how-to-file-complaint?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--I9LYVoV-oNtTQMO05y8FVs2obRpWT2vwIhXltsSE4Qv8sbfteHAHw1n8qaurrPjFriwmWO81W8m3EVcyOs7SD53ox-g&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
With new EMTALA option, CMS will take your complaints
Patients can now file complaints directly with the federal government if they were denied emergency care including emergency abortions on a new web portal, the Centers for Medicare & Medicaid Services announced yesterday. The Biden administration has said that such denials of care violate the Emergency Medical Treatment and Labor Act or EMTALA, a law that requires hospitals to provide emergency care to any patient.
The new portal is designed to make reporting denials of care easier for patients and help CMS, which enforces the federal law, to investigate patient claims. “We want to make sure that everyone knows their rights and can take action to help make sure the health care system is safe for everyone,” CMS Administrator Chiquita Brooks-LaSure said in a statement. The application of EMTALA to abortions is currently at the center of a Supreme Court case that will weigh whether an exception should be made in certain cases for emergency abortions.
EMTALA, a vital health law you’ve never heard of, is in danger
By Nicole HuberfeldApril 23, 2024
https://www.statnews.com/2024/04/23/supreme-court-abortion-idaho-emtala-case-could-imperil-emergency-care/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_o_BJPseXN0UEDWubs1TZtXBzc2QdrVxO8tmXu-YU0hC7sULLApjgQoI7msubE_cY6p4W8o8ZjHH8BHNLNTfzovfNn0A&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
Biden-Harris Administration Launches New Option to Report Potential Violations of Federal Law and Continue to Promote Patient Access to Stabilizing Emergency Care
https://www.hhs.gov/about/news/2024/05/21/biden-harris-administration-launches-new-option-report-potential-violations-federal-law-continue-promote-patient-access-stabilizing-emergency-care.html?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_xbuW0yBXtKbITlrG7S2y6mhR8HSGl21E82X0KCAHksTdA94YA__GLRJkaibQF4KGiFvlwIXwqa7j3yq9psRxo6s6MrA&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
Supreme Court judges wrestle with abortion access in emergency cases
Sarah Owermohle
By Sarah Owermohle April 24, 2024
https://www.statnews.com/2024/04/24/supreme-court-emergency-abortion-access/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9WjQuI3LIArlF3O4A645d6sy-XE4ONnX9v8LRRZ1U9YNrlyRLPH1J5OSf-AnzNFynlZyzWFmv2TfHtF6MViJXjJfCVSg&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
Off-label treatment for alcohol use disorder is linked to slower liver decline, study suggests Isabella Cueto By Isabella Cueto May 22, 2024
Off-label treatment for alcohol use disorder is linked to slower liver decline, study suggests
Isabella Cueto
By Isabella Cueto May 22, 2024
https://www.statnews.com/2024/05/22/alcohol-use-liver-disease-gabapentin/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-980jQInL_aLSDwCZAzNI1fkcem-HbE0Cd_h61H8FF0CG_j8gDwXynEl9vZHxKuOrNVLqTBQPgvLBrttAABIESzkw2l7w&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
An anti-seizure drug may help manage liver disease in patients with alcohol use disorder
Doctors only have three FDA-approved medications to manage alcohol use disorder. But STAT’s Isa Cueto reports on a new study that suggests anti-seizure drugs known as gabapentinoids could be an improvement over some of those approved drugs in treating alcohol-associated liver disease.
Among over 24,000 VA patients with alcohol use disorder, those who were prescribed gabapentinoids were less likely to experience progression of alcohol-associated liver disease compared to those who received an approved alcohol dependence drug, acamprosate. In veterans with pre-existing liver disease, 30.4% on acamprosate got worse compared to 25.8% on gabapentinoids.
The drugs may also be able to reduce the need to drink, which could “kill two birds with one stone,” said lead author Raj Shah: “Treat their pains as well as their alcohol use disorder.”
CDC asks states and cities to keep flu surveillance at peak levels because of bird flu threat Helen Branswell By Helen Branswell May 21, 2024
CDC asks states and cities to keep flu surveillance at peak levels because of bird flu threat
Helen Branswell
By Helen Branswell May 21, 2024
https://www.statnews.com/2024/05/21/h5n1-bird-flu-cdc-urges-summer-flu-surveillance/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_8bzrJVVKicKkNrOhvq4o6KAwUcxGEuwC9C6UrUMWfR7MNxM2XxctVT7-H3jHcydUqlvrdXnYNAzr6lekMxd12LETljg&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
While flu surveillance typically slows in late spring, this year will be different. STAT’s Helen Branswell reports that health officials are planning to maintain high levels of surveillance efforts through the summer due to concerns about the H5N1 bird flu virus. The Centers for Disease Control and Prevention asked state and local health authorities to keep a watchful eye for any signs that the virus is spreading human-to-human.
Should H5N1 begin spreading among people, one of the best defenses against another pandemic will be the world’s capacity to turn into a vaccine machine. But when exactly to start loading cargo ships with vaccines is a tricky question. “Get it right and you save lives. Hesitate, and lives will be lost. But making the call if the vaccine turns out not to be needed is not a cost-free decision either,” Branswell writes. Read more about how public health leaders and manufacturers weigh the odds.
When should we start making H5N1 vaccine, and who will make that decision? In short, it’s complicated
Helen Branswell
By Helen Branswell May 22, 2024
https://www.statnews.com/2024/05/22/h5n1-bird-flu-vaccine-questions-and-answers/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8zYPOFuIRhw-545oyV0DSJSPl0TeN6HayZBMNClYgO7660XwRTn_7iGVF9lzUWntZbEU5GhtB2q1bY70pgL9pNienbJA&_hsmi=308143698&utm_content=308143698&utm_source=hs_email
sábado, 25 de mayo de 2024
Viral Hostage Tape sleeping trend gains steam as doctors warn of potential dangers Health benefits are 'absolutely legit,' TikTok user writes Andrea Vacchiano By Andrea Vacchiano Fox News Published May 22, 2024 3:15pm EDT | Updated May 22, 2024 8:03pm EDT
Viral Hostage Tape sleeping trend gains steam as doctors warn of potential dangers
Health benefits are 'absolutely legit,' TikTok user writes
Andrea Vacchiano By Andrea Vacchiano Fox News
Published May 22, 2024 3:15pm EDT | Updated May 22, 2024 8:03pm EDT
https://www.foxnews.com/health/viral-hostage-tape-sleeping-trend-gains-steam-doctors-warn-potential-dangers
Second American contracts bird flu tied to dairy cows as CDC says risk of infection still low The Texas and Michigan farm workers suffered from conjunctivitis, or pink eye Andrea Vacchiano By Andrea Vacchiano Fox News Published May 22, 2024 9:12pm EDT
Second American contracts bird flu tied to dairy cows as CDC says risk of infection still low
The Texas and Michigan farm workers suffered from conjunctivitis, or pink eye
Andrea Vacchiano By Andrea Vacchiano Fox News
Published May 22, 2024 9:12pm EDT
https://www.foxnews.com/health/second-american-contracts-bird-flu-tied-dairy-cows-cdc-says-risk-infection-still-low
Despite growing concerns over bird flu, many US dairy workers have not received protective equipment A dairy worker in Michigan tested positive for bird flu, US said, marking the second human case since cattle tested positive in March Reuters Published May 23, 2024 10:43am EDT
Despite growing concerns over bird flu, many US dairy workers have not received protective equipment
A dairy worker in Michigan tested positive for bird flu, US said, marking the second human case since cattle tested positive in March
Reuters
Published May 23, 2024 10:43am EDT
https://www.foxnews.com/health/despite-growing-concerns-bird-flu-us-dairy-workers-not-received-protective-equipment
What to know about the new 'FLiRT' COVID variants Spokesman for Infectious Diseases Society of America said he has not seen evidence of uptick in disease, hospitalizations Reuters Published May 24, 2024 10:21am EDTWhat to know about the new 'FLiRT' COVID variants Spokesman for Infectious Diseases Society of America said he has not seen evidence of uptick in disease, hospitalizations Reuters Published May 24, 2024 10:21am EDT
What to know about the new 'FLiRT' COVID variants
Spokesman for Infectious Diseases Society of America said he has not seen evidence of uptick in disease, hospitalizations
Reuters
Published May 24, 2024 10:21am EDT
https://www.foxnews.com/health/what-know-new-flirt-covid-variants
Undercooked bear meat to blame for infecting family with rare roundworm parasite: CDC The 6 infected family members lived in South Dakota, Minnesota and Arizona, and ranged in age from 12 to 62 Brie Stimson By Brie Stimson Fox News Published May 24, 2024 7:19pm EDT | Updated May 24, 2024 8:25pm EDT
Undercooked bear meat to blame for infecting family with rare roundworm parasite: CDC
The 6 infected family members lived in South Dakota, Minnesota and Arizona, and ranged in age from 12 to 62
Brie Stimson By Brie Stimson Fox News
Published May 24, 2024 7:19pm EDT | Updated May 24, 2024 8:25pm EDT
https://www.foxnews.com/health/undercooked-bear-meat-blame-infecting-family-rare-roundworm-parasite-cdc
ADHD affects 1 in 9 kids in US, new report reveals: ‘Shame and stigma’ Experts share potential reasons for the spike — and how parents can help Melissa Rudy By Melissa Rudy Fox News Published May 24, 2024 4:11pm EDT
ADHD affects 1 in 9 kids in US, new report reveals: ‘Shame and stigma’
Experts share potential reasons for the spike — and how parents can help
Melissa Rudy By Melissa Rudy Fox News
Published May 24, 2024 4:11pm EDT
https://www.foxnews.com/health/adhd-affects-kids-us-new-report-reveals-shame-stigma
Mobile medical clinics bring health care directly to homeless veterans in 25 cities Portable clinics offer 'the services of a regular primary care clinic,' a coordinator said By Sunny Tsai Fox News Published May 25, 2024 8:38am EDT
Mobile medical clinics bring health care directly to homeless veterans in 25 cities
Portable clinics offer 'the services of a regular primary care clinic,' a coordinator said
By Sunny Tsai Fox News
Published May 25, 2024 8:38am EDT
https://www.foxnews.com/health/mobile-medical-clinics-bring-health-care-homeless-veterans-25-cities
Half of Americans not equipped to provide life-saving treatment in a crisis, poll finds Emergency room physicians provide tips on how people can be better prepared Melissa Rudy By Melissa Rudy Fox News Published May 22, 2024 8:12pm EDT
Half of Americans not equipped to provide life-saving treatment in a crisis, poll finds
Emergency room physicians provide tips on how people can be better prepared
Melissa Rudy By Melissa Rudy Fox News
Published May 22, 2024 8:12pm EDT
https://www.foxnews.com/health/half-americans-equipped-provide-life-saving-treatment-crisis-poll-finds
Fish oil supplements linked to greater first-time heart attack risk in study: ‘Not universally good or bad' A cardiologist, two dietitians shared cautions, tips on fish oil supplements and new study: ‘More isn’t always better’ Melissa Rudy By Melissa Rudy Fox News Published May 23, 2024 7:15pm EDT
Fish oil supplements linked to greater first-time heart attack risk in study: ‘Not universally good or bad'
A cardiologist, two dietitians shared cautions, tips on fish oil supplements and new study: ‘More isn’t always better’
Melissa Rudy By Melissa Rudy Fox News
Published May 23, 2024 7:15pm EDT
https://www.foxnews.com/health/fish-oil-supplements-linked-greater-first-time-heart-attack-risk-not-universally-good-bad
5 myths about schizophrenia, according to a mental health expert: ‘Huge stigma’ For World Schizophrenia Day, a psychiatric nurse practitioner shares some of the most common misconceptions Melissa Rudy By Melissa Rudy Fox News Published May 24, 2024 5:00am EDT
5 myths about schizophrenia, according to a mental health expert: ‘Huge stigma’
For World Schizophrenia Day, a psychiatric nurse practitioner shares some of the most common misconceptions
Melissa Rudy By Melissa Rudy Fox News
Published May 24, 2024 5:00am EDT
https://www.foxnews.com/health/myths-schizophrenia-according-mental-health-expert-huge-stigma
Study explains why the brain can robustly recognize images, even without color
https://news.mit.edu/2024/study-explains-why-brain-robustly-recognizes-images-even-without-color-0523
The findings also reveal why identifying objects in black-and-white images is more difficult for individuals who were born blind and had their sight restored.
Anne Trafton | MIT News
Publication Date:May 23, 2024
How Neurons Build a 3-D Vascular Structure to Keep the Retina Healthy
https://www.ucsf.edu/news/2024/05/427661/how-neurons-build-3-d-vascular-structure-keep-retina-healthy
Understanding how intricate networks of blood vessels in the eye and brain are formed could inspire new treatments for conditions like diabetic retinopathy and stroke.
By Robin Marks
Excellent to the “Core”: World Class Neuroimaging at NIMH
https://www.nimh.nih.gov/about/director/messages/2024/excellent-to-the-core-world-class-neuroimaging-at-nimh?utm_campaign=75&utm_medium=email&utm_source=govd
The National Institute of Mental Health (NIMH) has been a world leader in developing and implementing advanced brain imaging technology. These sophisticated tools allow us to better understand brain function, disease signatures, and potential treatment options.
To learn about some of our greatest technological advancements, read our guest-written Director's message from Peter Bandettini, Ph.D., Chief of the Section on Functional Imaging Methods and Director of the Functional Magnetic Resonance Imaging Core Facility, within NIMH's Intramural Research Program.
High H5N1 Influenza Levels Found in Mice Given Raw Milk from Infected Dairy Cows
https://www.niaid.nih.gov/news-events/high-h5n1-influenza-levels-found-mice-given-raw-milk-infected-dairy-cows?utm_campaign=+60723523&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=
In NIAID-funded research results published today in the New England Journal of Medicine, mice administered raw milk samples from dairy cows infected with H5N1 influenza experienced high virus levels in their respiratory organs and lower virus levels in other vital organs. The results suggest that consumption of raw milk by animals poses a risk for H5N1 infection and raises questions about its potential risk in humans.
Additionally, the researchers also tested to determine which temperatures and time intervals inactivate H5N1 virus in raw milk from dairy cows. Four milk samples with confirmed high H5N1 levels were tested at 63 degrees Celsius (145.4 degrees Fahrenheit) for 5, 10, 20 and 30 minutes, or at 72 degrees Celsius (161.6 degrees Fahrenheit) for 5, 10, 15, 20 and/or 30 seconds. Each of the time intervals at 63℃ successfully killed the virus. At 72℃, virus levels were diminished but not completely inactivated after 15 and 20 seconds. The authors emphasize, however, that their laboratory study was not identical to large-scale industrial pasteurization of raw milk and reflect experimental conditions that should be replicated with direct measurement of infected milk in commercial pasteurization equipment.
In a separate experiment, the researchers stored raw milk infected with H5N1 at 4℃ (39.2 degrees Fahrenheit) for five weeks and found only a small decline in virus levels, suggesting that the virus in raw milk may remain infectious when maintained at refrigerated temperatures.
Watch the Replay: The promise of CAR macrophages
https://go.drugdiscoverynews.com/ddn_webinar_recording_the-promise-of-car-macrophages
Macrophages are potent killer cells adept at consuming and eliminating abnormal cells in the body. This, coupled with their unique ability to penetrate the solid tumor microenvironment and mediate immunosuppression, makes them attractive for a new type of chimeric antigen receptor (CAR) therapy. In this webinar, Denise Montell will discuss how studies on cell movement and phagocytosis in fruit flies revealed a universally conserved protein with the potential to enhance CAR macrophage activity and targeting.
Topics to be covered
• Studying cell movement to uncover the mechanism behind a rare human immunodeficiency
• Harnessing this molecular mechanism to enhance CAR macrophage immunotherapy
Drug Discovery News Webinars
webinars@ddn-news.com
Psilocybin for Mental Health and Addiction: What You Need To Know
https://www.nccih.nih.gov/health/psilocybin-for-mental-health-and-addiction-what-you-need-to-know?nav=govd
Psilocybin is a plant chemical that comes from certain types of mushrooms. It’s considered a psychedelic drug—a type of drug that affects how the brain processes a chemical called serotonin. At certain doses, it can change people’s moods, thoughts, and perceptions.
Researchers are interested in the potential of psychedelic drugs such as psilocybin to treat mental health conditions including depression, anxiety, existential distress in serious medical illnesses, post-traumatic stress disorder, and addiction. Psilocybin is also being studied as a possible treatment for chronic pain.
People’s reactions to psilocybin can be unpredictable and can include unpleasant experiences involving extreme fear, confusion, and panic. Psilocybin can also have other side effects such as increased blood pressure and heart rate, nausea, poor sleep, paranoia, and hallucinations. Experts recommend that people should only take psilocybin while under the care of a trained therapist or facilitator.
viernes, 24 de mayo de 2024
CAR T-CELL THERAPY: DO THE BENEFITS OUTWEIGH THE RISKS?
CAR T-Cell Therapy: Do the Benefits Outweigh the Risks?
By Ivanhoe Broadcast News on June 2, 2024
https://www.ivanhoe.com/?p=33288&preview=1&_ppp=533fbe6ebc
SILVER-HAIRED AVATARS COACH SENIORS THROUGH RECOVERY
Silver-Haired Avatar Coach Seniors Through Recovery
By Ivanhoe Broadcast News on June 1, 2024
https://www.ivanhoe.com/?p=33285&preview=1&_ppp=cb0ca58574
INDUCTION THERAPY: REVOLUTIONIZING TONGUE CANCER TREATMENT
Induction Therapy: Revolutionizing Tongue Cancer Treatment
By Ivanhoe Broadcast News on May 31, 2024
https://www.ivanhoe.com/?p=33352&preview=1&_ppp=7b42d68b0f
THE NEW “NO SURGERY, NO WIRES” PACEMAKER
The New “No Surgery, No Wires” Pacemaker
By Ivanhoe Broadcast News on May 30, 2024
https://www.ivanhoe.com/?p=33345&preview=1&_ppp=93094ee8ed
BUILDING A SMARTER BIONIC PANCREAS FOR TYPE 1 DIABETES
Building a Smarter Bionic Pancreas for Type 1 Diabetes
By Ivanhoe Broadcast News on May 29, 2024
https://www.ivanhoe.com/?p=33337&preview=1&_ppp=ba0b215221
SKATER PUTS RARE CONDITION ON ICE: CRMO
Skater Puts Rare Condition on Ice: CRMO
By Ivanhoe Broadcast News on May 28, 2024
https://www.ivanhoe.com/?p=33330&preview=1&_ppp=8d2fdb754c
STOP SHAKING: FOCUSED ULTRASOUND TARGETS TREMORS
Focused Ultrasound Targets Tremors
By Ivanhoe Broadcast News on May 27, 2024
https://www.ivanhoe.com/?p=33321&preview=1&_ppp=819fa3984f
Researchers Map Neural Connections Key to Wakefulness in the Human Brain Posted on May 23rd, 2024 by Dr. Monica M. Bertagnolli
https://directorsblog.nih.gov/2024/05/23/researchers-map-neural-connections-key-to-wakefulness-in-the-human-brain/
Human consciousness requires a person to be both awake and aware. While neuroscientists have learned a great deal from research about the underlying brain networks that sustain awareness, surprisingly little has been known about the networks that keep us awake.
Now, an NIH-supported team of researchers has mapped the connectivity of a neural network they suggest is essential for wakefulness, or arousal, in the human brain. According to the researchers, this advance, reported in Science Translational Medicine, is essential for understanding human consciousness. It may also lead to new ways of understanding what happens in the brain when people lose consciousness, with potentially important implications for treating those who have entered a coma or vegetative state.
jueves, 23 de mayo de 2024
Learn with the Open Academy
The EURORDIS Open Academy accompanies patient advocates by offering rare disease-specific comprehensive training programmes that empower advocates with the knowledge, skills and confidence they need to engage with different stakeholders as equal partners. Our Schools offer a blended learning approach including eLearning courses, webinars and in-person training as well as research visits and networking opportunities.
https://openacademy.eurordis.org/
New: e-learning courses translated into Spanish
We are excited to announce the launch of six popular e-learning courses, now available in Spanish! Translated from the original courses in English, they cover a range of coveted topics designed to enhance your skills and knowledge. Whether you are looking to learn more about advocacy or communications, these courses provide comprehensive, accessible and high-quality content tailored for Spanish-speaking learners. Don't miss this opportunity to learn in your preferred language.
We are committed to inclusivity and accessibility, and this expansion reflects our dedication to serving a diverse global rare disease community. Stay tuned for further translations of selected courses in Spanish and several additional languages!
Spread the word with your Spanish speaking community and join us on our journey to train more patient advocates around the world!
One of NIST’s Most Prolific Inventors Is Also Our Director — and She’s Still an Inventor at Heart May 22, 2024
miércoles, 22 de mayo de 2024
US dental care crisis: It should not be a luxury to keep your teeth in your mouth If people don’t receive high-quality dental care, they are in danger of living their lives in severe pain Sen. Bernie Sanders By Sen. Bernie Sanders Fox News Published May 22, 2024 5:00am EDT
US dental care crisis: It should not be a luxury to keep your teeth in your mouth
If people don’t receive high-quality dental care, they are in danger of living their lives in severe pain
Sen. Bernie Sanders By Sen. Bernie Sanders Fox News
Published May 22, 2024 5:00am EDT
https://www.foxnews.com/opinion/us-dental-care-crisis-should-not-be-luxury-keep-teeth-your-mouth
Spinal cord treatment restores function for paralyzed patients in study: ‘New hope’ Study finds 90% of participants reported improved function or strength in their upper limbs Melissa Rudy By Melissa Rudy Fox News Published May 21, 2024 4:50pm EDT
Spinal cord treatment restores function for paralyzed patients in study: ‘New hope’
Study finds 90% of participants reported improved function or strength in their upper limbs
Melissa Rudy By Melissa Rudy Fox News
Published May 21, 2024 4:50pm EDT
https://www.foxnews.com/health/spinal-cord-treatment-restores-function-paralyzed-patients-study-new-hope
Ask a doc: 'Is it dangerous to swallow gum?' Two medical experts answer the age-old question: ‘Not a good habit’ Melissa Rudy By Melissa Rudy Fox News Published May 20, 2024 2:53pm EDT
Ask a doc: 'Is it dangerous to swallow gum?'
Two medical experts answer the age-old question: ‘Not a good habit’
Melissa Rudy By Melissa Rudy Fox News
Published May 20, 2024 2:53pm EDT
https://www.foxnews.com/health/ask-doc-is-it-dangerous-swallow-gum
Could your car make you sick? Study highlights potentially cancerous toxins in vehicles Experts warn of common chemical culprits lurking in car cabins By Amy McGorry Fox News Published May 18, 2024 5:00am EDT
Could your car make you sick? Study highlights potentially cancerous toxins in vehicles
Experts warn of common chemical culprits lurking in car cabins
By Amy McGorry Fox News
Published May 18, 2024 5:00am EDT
https://www.foxnews.com/health/could-car-make-you-sick-study-highlights-potentially-cancerous-toxins-vehicles
Heart attacks more likely during presidential elections and other stressful times, study shows People with high stress, along with anxiety or depression, are more susceptible to cardiac arrest, researchers found Angelica Stabile By Angelica Stabile Fox News Published May 20, 2024 5:00am EDT
Heart attacks more likely during presidential elections and other stressful times, study shows
People with high stress, along with anxiety or depression, are more susceptible to cardiac arrest, researchers found
Angelica Stabile By Angelica Stabile Fox News
Published May 20, 2024 5:00am EDT
https://www.foxnews.com/health/heart-attacks-more-likely-presidential-elections-other-stressful-times-study-shows
Many families take patients off life support too soon after traumatic brain injuries: study Some patients may be likely to survive and recover if given more time, researchers found Melissa Rudy By Melissa Rudy Fox News Published May 19, 2024 8:12pm EDT
Many families take patients off life support too soon after traumatic brain injuries: study
Some patients may be likely to survive and recover if given more time, researchers found
Melissa Rudy By Melissa Rudy Fox News
Published May 19, 2024 8:12pm EDT
https://www.foxnews.com/health/many-families-take-patients-life-support-too-soon-traumatic-brain-injuries-study
Three women — ages 41, 55 and 64 — share their secrets to better health and longevity For Women’s Health Month, 3 mothers and grandmothers revealed how they're defying their chronological ages Melissa Rudy By Melissa Rudy Fox News Published May 21, 2024 5:41am EDT
Three women — ages 41, 55 and 64 — share their secrets to better health and longevity
For Women’s Health Month, 3 mothers and grandmothers revealed how they're defying their chronological ages
Melissa Rudy By Melissa Rudy Fox News
Published May 21, 2024 5:41am EDT
https://www.foxnews.com/health/three-women-share-secrets-better-health-longevity
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