domingo, 21 de enero de 2024

Genetic risk and likelihood of prostate cancer detection on first biopsy by ancestry. Kyung Min Lee et al. J Natl Cancer Inst 2024 1

https://phgkb.cdc.gov/PHGKB/phgHome.action?action=all%20hot%20topics From the abstract: "This cross-sectional retrospective analysis examines the association between a polygenic hazard score (PHS290) and risk of prostate cancer diagnosis upon first biopsy in male Veterans using two-sided tests. Our analysis included 36,717 Veterans (10,297 of African ancestry). Unadjusted rates of positive first prostate biopsy increased with higher genetic risk (low risk: 34%, high risk: 58%; p?

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