lunes, 27 de abril de 2020

Linking Synaptic Specificity to Hippocampal Circuit Function

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 Fluorescence 
 The latest fluorescence news from NewsMedical 
 What is Time-Resolved Fluorescence Spectroscopy?Linking Synaptic Specificity to Hippocampal Circuit Function

The developmental transition between axon guidance and synapse formation is critical for circuit assembly but still poorly understood. This webinar presents evidence that this key transition can be regulated by axon guidance cues switching their function to regulate synaptogenesis with subcellular specificity.

The presentation discusses Bruker's uncovering of a novel role for the axon guidance molecule Robo2 in excitatory synapse formation in the mouse hippocampus. Cell-autonomous deletion of Robo2 from CA1 pyramidal neurons (PNs) leads to a drastic reduction of the number of excitatory synapses specifically in proximal dendritic compartments.

Join this free Webinar on May 4 to learn more.

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The monotonous and often laborious practice of manually counting cells on a hemocytometer has been significantly improved in recent years with the introduction of numerous automated cell-counting instruments. Even with these improvements however, measuring cell concentration and viability for high numbers of samples can still create a bottleneck in many industrial processes and large scale experiments.
 
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 Novel 3D Imaging Technology Makes Fluorescence Microscopy More Efficient
 
Novel 3D Imaging Technology Makes Fluorescence Microscopy More EfficientA research team led by Dr Kevin Tsia from the University of Hong Kong (HKU), developed a new optical imaging technology -- Coded Light-sheet Array Microscopy (CLAM) -- which can perform 3D imaging at high speed, and is power efficient and gentle to preserve the living specimens during scanning at a level that is not achieved by existing technologies.
 
 
 New technique for imaging proteins in 3D
 
New technique for imaging proteins in 3DA team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)--a U.S. Department of Energy Office of Science User Facility at DOE's Brookhaven National Laboratory--have demonstrated a new technique for imaging proteins in 3-D with nanoscale resolution.
 
 
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