viernes, 7 de diciembre de 2018

Medical News | Medical Articles | Pharmacy / Pharmacology - Dec 07, 2018 Edition

Medical News | Medical Articles

 December 7, 2018 
 Pharmacy / Pharmacology 
 The latest pharmacy / pharmacology news from News Medical 
 #ALT#Host Cell Protein Analysis using Mass Spectometry

It is essential to identify HCPs that may affect drug safety and stability. ELISA assays are currently the gold standard for QC applications, but there are long lead times for new assays based on process changes.

This webinar describes the main advantage of mass spectrometry for HCP analysis, including the ability for unbiased, highly sensitive detection.

Watch Webinar Now
   Study examines timing of musculoskeletal adverse events that develop during statin therapy
Statins have been linked with muscle pain and other musculoskeletal adverse events in some patients. A new Pharmacology Research & Perspectives study has examined the timing of MAEs that develop during statin therapy and determined whether concomitant drugs used concurrently with statin therapy shifts the timing of MAEs.
   Toxicologists and pharmacologists meet at international conference in Adelaide
Experts will meet to discuss the latest discoveries in drugs and how best to use existing ones as effectively and safely as possible, at an international conference in Adelaide this week (27-30 November).
 Diets supplemented with extract of soursop leaves can prevent fibromyalgia symptoms
Researchers from the Department of Pharmacology at the University of Seville have recently published a study in which they state that diets supplemented with aqueous extract of Annona muricata L. leaves can prevent the symptoms associated with fibromyalgia, so improving the lives of these patients.
 Study highlights need for interventions to improve statin use among older adults
In a British Journal of Clinical Pharmacology study of older adults prescribed statins, first-year nonadherence and discontinuation rates were high.
 New pharmacological agent shows promise for prevention of heart rhythm disorders
A new pharmacological agent demonstrates promising results for the prevention of a wide range of heart rhythm disorders, including both cardiac and brain injury-induced arrhythmias.
 Prostate cancer patients receiving androgen deprivation therapy may have higher heart failure risk
Androgen deprivation therapy was associated with a 72 percent higher risk of heart failure in a study of patients with prostate cancer.
 Cancer risk linked to mobile phone radiation in rats but cannot be extrapolated to humans
Cancer risk linked to mobile phone radiation in rats but cannot be extrapolated to humansA new study on laboratory rats has shown that mobile phone radiation exposure is linked to cancers of the brain, heart and the adrenal glands. The rats however were exposed to very high amounts of radiation which is much more than what humans are exposed when they use cell phones.
 Surprising discovery about BH4 may rekindle interest in once-promising pathway
In 2013, renowned Boston Children's Hospital pain researcher Clifford Woolf, MB, BCh, PhD, and chemist Kai Johnsson, PhD, his fellow co-founder at Quartet Medicine, believed they held the key to non-narcotic pain relief.
 Drug used to treat PTSD does not reduce suicidal thinking, may worsen nightmares and insomnia
Nightmares and insomnia often accompany posttraumatic stress disorder and increase suicide risk.
 Study could provide novel treatment strategy for potentially blinding problem
An enzyme known to help our liver get rid of ammonia also appears to be good at protecting our retina, scientists report.
 New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability
From January 1, 2019, the German Research Foundation will be funding the new Collaborative Research Center 1361 on Regulation of DNA Repair & Genome Stability.
 Podcast: KHN’s ‘What the Health?’ Reading the tea leaves in blue wave’s wake
This week, "What the Health?" panelists discuss, among other things, how the House Democrats' leadership battle could affect the congressional health policy agenda.
 UH pharmaceutical scientist developing new drug to treat children with rare genetic disorder
A University of Houston pharmaceutical scientist is developing a new drug which could bring relief to children suffering with Familial Adenomatous Polyposis, a rare genetic disorder characterized by hundreds - if not thousands - of colorectal polyps.
 Discovery would help specify role of genetics in the development of neuropsychiatric disorders
Neurobiologists from I.M. Sechenov First Moscow State Medical University confirmed that stress in early age affects the mice with activated and deactivated CDH13 gene in different ways.
 New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis
The use of a new class of drugs in the treatment of type 2 diabetes, so called SGLT2 inhibitors, are linked to a twofold increased risk for lower-limb amputation as well as diabetic ketoacidosis, a serious diabetes complication.
 Natural Treatments for Acne that Work
Natural Treatments for Acne that WorkAcne is a common skin condition that will affect most individuals at some point during their lifetime. More severe cases may benefit from oral antibiotics and topical treatments.
 Ribosome (mRNA) Display: An Overview
Ribosome (mRNA) Display: An OverviewRibosome display is a self-read technology for in vitro selection and evolution of proteins encoded by DNA libraries.
 Using Chromatography to Evaluate the Safety of Food Packaging
Using Chromatography to Evaluate the Safety of Food PackagingSeveral techniques have been tried and tested for the analysis of food packaging, or food contact materials, but chromatography is the preferred method.
 Innovative Lab Capabilities for Assay Platforms
Innovative Lab Capabilities for Assay PlatformsACROBiosystems provides a number of assay platforms to their scientists, recently adding Multiplexing, TCR Screening, and qPCR services.
 Fetal kicks may allow the baby to 'map' their own body, suggests research
The kicks a mother feels from her unborn child may allow the baby to 'map' their own body and enable them to eventually explore their surroundings, suggests new research led by UCL in collaboration with UCLH.
 Are Artificial Food Flavors and Colorings Harmful?
Are Artificial Food Flavors and Colorings Harmful?Food flavors and colorings are commonly used to enhance the natural properties of chemical substances found in foods. Food colorings may be used to make foods look more appealing, while food flavorings are added to enhance existing flavor or add new flavor to otherwise bland products.
 Game-Changers in Western Blotting and Protein Analysis
Game-Changers in Western Blotting and Protein AnalysisAn interview with Ramya Prabakaran & Melody Chang from GenScript, discussing the development of automated systems that improve outcomes for western blotting.
 Oral antibiotic shows promise to cure uncomplicated gonorrhea
An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.
 MBF Bioscience
MBF BioscienceWe design quantitative imaging and visualization software for stereology, neuron reconstruction, vascular analysis, c. elegans behavior analysis and medical education - integrated with the world’s leading microscope systems - to empower your research.
 Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure
Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit, MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality.
 House Dems in new seats of power will steer health policy, attack drug prices
House Dems in new seats of power will steer health policy, attack drug pricesFor the first time since passing the Affordable Care Act, Democrats will soon control the House of Representatives and its powerful health committees. But Republicans' tightened grip on the Senate means those hoping for another round of dramatic, progressive reforms may be disappointed.
 Study: Impact of opioid epidemic on children differs by state
A new report released by the Drug Enforcement Administration finds most overdose deaths are caused by prescription drugs, including opioids.
 Study finds rapid increase in overdose deaths involving amphetamines and methamphetamines
The number of overdose deaths involving methamphetamines and amphetamines in the state of Ohio increased more than 5,000 percent over the course of eight years, according to data collected by the Ohio Alliance for Innovation in Population Health.
 Salk researchers report new methods to identify AD drug candidates with anti-aging properties
Old age is the greatest risk factor for many diseases, including Alzheimer's disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds.
 NIH awards $3.4 million to UC researchers to study gastrointestinal lymphatic system
A team of researchers at the University of Cincinnati College of Medicine have been awarded $3.4 million by the National Institutes of Health to study the role of the gastrointestinal lymphatic system in dietary nutrient absorption and the transport of signaling molecules.
 GW study examines impact of nervous system on non-alcoholic fatty liver disease
GW study examines impact of nervous system on non-alcoholic fatty liver diseaseNon-alcoholic fatty liver disease, the accumulation of fat in the liver of people who drink little or no alcohol, affects 1 in 3 Americans. NAFLD is a significant risk factor for Type 2 diabetes, insulin resistance, and hepatic carcinoma, and incidence of the disease is increasing with the growing obesity epidemic in the United States.
 RNAi therapy shown to alleviate preeclampsia in animal model
RNAi therapy shown to alleviate preeclampsia in animal modelResearcher have used a small interfering RNA (siRNA) to reduce preeclampsia symptoms in an animal model. The approach could provide a new way of treating preeclampsia in humans.
 Study examines trends in opioids prescribed for children and adolescents
While the opioid crisis remains a major public health concern in the United States for people of all ages, relatively little research has been conducted in younger populations.
 First biosimilar approved by FDA for treatment of adult patients with non-Hodgkin’s lymphoma
The U.S. Food and Drug Administration today approved Truxima (rituximab-abbs) as the first biosimilar to Rituxan (rituximab) for the treatment of adult patients with CD20-positive, B-cell non-Hodgkin's lymphoma (NHL) to be used as a single agent or in combination with chemotherapy.
 Insights from the Shunde Biomedical Industry Investment Promotion Conference
Insights from the Shunde Biomedical Industry Investment Promotion ConferenceFrom November 14-17, the 2018 Shunde Biomedical Industry Investment Promotion Conference was successfully held at the Ramada Plaza Hotel, Shunde, GuangDong, China
 Using Blockchain in Health Care
Using Blockchain in Health CareBlockchain can lead to an increase in patient-institution confidence and we are seeing it spread quickly throughout pharmaceutical and medical industries.
 Four Reasons to Hire a Freelance Medical Writer
Four Reasons to Hire a Freelance Medical WriterAt every step of medical research or product development, there is a writing exercise involved. Whether it is a grant application or medical product description, all healthcare communications have to be aligned with regulatory, ethical and legal standards.
 Separating Drugs by Chirality
Separating Drugs by ChiralityAverica can provide compounds after processing - in milligrams or in kilograms. Samples which are very small may require up to a few days for processing, but all processes developed with Averica can be scaled up or down to fit the needs of the specific project.
 Associating T-Cell Receptors with Biotinylated CD3E
Associating T-Cell Receptors with Biotinylated CD3EA T-cell receptor (TCR) cannot signal on its own. To do so, it must link with a CD3 coreceptor, which has become a focal point of pharmaceutical research.
 How do SSRIs Interact with Monoamine Transporters?
How do SSRIs Interact with Monoamine Transporters?Selective serotonin reuptake inhibitors (SSRIs) block the reuptake of serotonin by the serotonin transporter (SERT) protein, a type of monoamine transporter.

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