HIV/AIDS Medicines
National Institutes of Health
Other Languages
In the early 1980s, when the HIV/AIDS epidemic began, patients rarely lived longer than a few years. But today, there are many effective medicines to fight the infection, and people with HIV have longer, healthier lives.
There are five major types of medicines:
- Reverse transcriptase (RT) inhibitors - interfere with a critical step during the HIV life cycle and keep the virus from making copies of itself
- Protease inhibitors - interfere with a protein that HIV uses to make infectious viral particles
- Fusion inhibitors - block the virus from entering the body's cells
- Integrase inhibitors - block an enzyme HIV needs to make copies of itself
- Multidrug combinations - combine two or more different types of drugs into one
These medicines help people with HIV, but they are not perfect. They do not cure HIV/AIDS. People with HIV infection still have the virus in their bodies. They can still spread HIV to others through unprotected sex and needle sharing, even when they are taking their medicines.
NIH: National Institute of Allergy and Infectious Diseases
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- CDC Vital Signs: Daily Pill Can Prevent HIV (Centers for Disease Control and Prevention)Also in Spanish
- Are You Taking Medication as Prescribed? (Food and Drug Administration)
- CDC Vital Signs: HIV Care Saves Lives Also in Spanish
- Drug Dosing Toolkit (Department of Veterans Affairs)
- Drug Resistance (AIDSinfo)Also in Spanish
- Following an HIV Regimen: Steps to Take Before and After Starting HIV Medicines (AIDSinfo)Also in Spanish
- HIV Medication Adherence (AIDSinfo)Also in Spanish
- HIV Medicines and Side Effects (AIDSinfo)Also in Spanish
- HIV Resistance Testing (New Mexico AIDS Education and Training Center)Also in Spanish
- HIV Treatment Overview (AIDS.gov)
- Post-Exposure Prophylaxis (AIDS.gov)
- Post-Exposure Prophylaxis (PEP) (AIDSinfo)Also in Spanish
- Pre-Exposure Prophylaxis (PrEP) (AIDS.gov)
- PrEP (Pre-Exposure Prophylaxis) 101 (Centers for Disease Control and Prevention)Also in Spanish
- Recreational Drugs and HIV (New Mexico AIDS Education and Training Center)Also in Spanish
- Side Effects of HIV Medicines: HIV and Diabetes (AIDSinfo)Also in Spanish
- Side Effects of HIV Medicines: HIV and Hepatotoxicity (AIDSinfo)Also in Spanish
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- Side Effects of HIV Medicines: HIV and Osteoporosis (AIDSinfo)Also in Spanish
- Side Effects of HIV Medicines: HIV and Rash (AIDSinfo)Also in Spanish
- What to Start: Selecting a First HIV Regimen (AIDSinfo)Also in Spanish
- When to Start Antiretroviral Therapy (AIDSinfo)
- Antiretroviral Drugs Used in the Treatment of HIV Infection (Food and Drug Administration)
- HIV Treatment: What is a Drug Interaction? (AIDSinfo)Also in Spanish
- What is an Investigational HIV Drug? (AIDSinfo)Also in Spanish
- Drugs That Fight HIV-1 (AIDSinfo) - PDF
- ClinicalTrials.gov: Anti-HIV Agents (National Institutes of Health)
- ClinicalTrials.gov: Antiretroviral Therapy, Highly Active (National Institutes of Health)
- ClinicalTrials.gov: Pre-Exposure Prophylaxis (National Institutes of Health)
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- AIDSinfo Glossary (AIDSinfo)Also in Spanish
- AIDSinfo (Department of Health and Human Services)Also in Spanish
- HIV.gov (AIDS.gov)
- NIAID Division of AIDS (National Institute of Allergy and Infectious Diseases)
- FDA-Approved HIV Medicines (AIDSinfo)Also in Spanish
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